Search results for "cycle"
showing 10 items of 3119 documents
Direct arylation of heterocycles: the performances of ferrocene-based polyphosphane ligands in palladium-catalyzed C-H bond activation
2010
International audience; The palladium-catalyzed direct arylation of alkylated- furan, thiophene, and thiazole and benzoxazole heterocycles with electronically and sterically deactivated bromoarenes was selectively and efficiently promoted by ferrocenyl polyphosphanes. In this C[BOND]H bond activation reaction of heteroaromatics, the performances of polydentate di-, tri-, and tetraphosphane ligands were compared, showing that the triphosphane 1,1′,2-tris(diphenylphosphino)-4-tert-butylferrocene 3 was the most effective for the coupling. The introduction of more electron-donating (iPr) or electron-withdrawing (furyl) groups on the phosphorus atoms did not improve the ligand performances. The …
Multiple Roles of Isocyanides in Palladium-Catalyzed Imidoylative Couplings: A Mechanistic Study
2016
International audience; Kinetic, spectroscopic and computational studies examining a palladium-catalyzed imidoylative coupling highlight the dual role of isocyanides as both substrates and ligands for this class of transformations. The synthesis of secondary amides from aryl halides and water is presented as a case study. The kinetics of the oxidative addition of ArI with RNC-ligated Pd-0 species have been studied and the resulting imidoyl complex [(ArC=NR)Pd(CNR)(2)I] (Ar=4-F-C6H4, R = tBu) has been isolated and characterized by X-ray diffraction. The unprecedented ability of this RNC-ligated imidoyl-Pd complex to undergo reductive elimination at room temperature to give the amide in the p…
Dehydrogenative Anodic C−C Coupling of Phenols Bearing Electron‐Withdrawing Groups
2019
Abstract We herein present a metal‐free, electrosynthetic method that enables the direct dehydrogenative coupling reactions of phenols carrying electron‐withdrawing groups for the first time. The reactions are easy to conduct and scalable, as they are carried out in undivided cells and obviate the necessity for additional supporting electrolyte. As such, this conversion is efficient, practical, and thereby environmentally friendly, as production of waste is minimized. The method features a broad substrate scope, and a variety of functional groups are tolerated, providing easy access to precursors for novel polydentate ligands and even heterocycles such as dibenzofurans.
Insights into how nucleotide supplements enhance the peroxidase-mimicking DNAzyme activity of the G-quadruplex/hemin system
2012
Since the initial discovery of the catalytic capability of short DNA fragments, this peculiar enzyme-like property (termed DNAzyme) has continued to garner much interest in the scientific community because of the virtually unlimited applications in developing new molecular devices. Alongside the exponential rise in the number of DNAzyme applications in the last past years, the search for convenient ways to improve its overall efficiency has only started to emerge. Credence has been lent to this strategy by the recent demonstration that the quadruplex-based DNAzyme proficiency can be enhanced by ATP supplements. Herein, we have made a further leap along this path, trying first of all to deci…
Life Cycle Assessment of a compact Desiccant Evaporative Cooling system: The case study of the “Freescoo”
2016
Abstract The paper aims at exploring the performances of a compact Desiccant Evaporative Cooling system called “Freescoo” (Free Solar Cooling) in comparison to standard conventional technologies. The Freescoo – that aims at applications in the residential sector and in small office buildings and includes a photovoltaic–thermal system – is analyzed, its monitored performance discussed and reported: under cooling conditions an Energy Efficiency Ratio of 12.8 is calculated, that reaches 50.7 if also photovoltaic generation is considered. To assess the performance of the proposed system a Life Cycle Assessment study was performed to investigate the system covering all its life, from the product…
ADVANCED SOLAR ASSISTED DESICCANT AND EVAPORATIVE COOLING SYSTEM EQUIPPED WITH WET HEAT EXCHANGERS
2011
Abstract This work concerns an innovative solar assisted desiccant and evaporative cooling (DEC) system for building air conditioning. In this system, air-to-air packaged wet heat exchangers are used to maximize the exploitation of the evaporative cooling potential associated with the exhaust air stream. The thermodynamic cycle is first theoretically described, and then an example of a real application is shown. The system presented is an experimental DEC system originally installed at the beginning of 2008 at the Solar Laboratory of the University of Palermo and recently modified and updated. These modifications have been implemented with the aim to foster some problems related to the conv…
Second Generation of Freescoo Solar DEC Prototypes for Residential Applications
2015
Freescoo is an innovative all-in-one compact solar Desiccant Evaporative Cooling (DEC) air conditioner concept. Results of the first prototype developed were presented at SHC Conference last year. Now a second generation of freescoo prototypes for applications in residential and small office buildings have been installed in Italy at ENEA Casaccia and at UNIPA. The thermodynamic cycle is based on the use of fixed and cooled adsorption beds and advanced evaporative cooling concepts. The adsorption bed, which is a fin and tube heat exchanger packed with silica gel grains, allows simultaneous dehumidification and cooling of the process air. The indirect evaporative cooling process, operated dow…
Monitoring of the action of drugs in melanoma cells by dynamic laser speckle
2014
Abstract. This work presents the development of a protocol based on the dynamic laser speckle designed tomonitor the reaction of cancer cells of line MEL-RC08 to the application of the drug Colcemid in two differentconcentrations: 0.2 and 0.4 μg∕mL. The protocol was designed using the forward scattering approach with anHe-Ne laser of 632.8 nm illuminating the samples, a control, and two variations of Colcemid, being monitoredalong 8 h. The data were analyzed numerically in the time and in the frequency domain, and the results pre-sented the ability of the technique to monitor the action of the drug, particularly Colcemid (0.4 μg∕mL). © 2014Society of Photo-Optical Instrumentation Engineers …
Significance of the Tambien Group (Tigrai, N. Ethiopia) for Snowball Earth events in the Arabian–Nubian Shield
2003
Abstract Juvenile continental crust of the Arabian–Nubian Shield (ANS) formed within a Neoproterozoic supercontinent cycle. Subsequent late Neoproterozoic deposition overlapped a series of dramatic climatic events that are unparalleled in subsequent Phanerozoic time, as proposed by the “Snowball Earth” hypothesis. In particular, extreme negative δ 13 C excursions coincident with glacial diamictite and cap carbonate sequences imply that profound carbon flux changes accompanied widespread glacial transitions (Snowball Events). Such a succession appears to be partially preserved in metasediments of the diamictite-bearing Tambien Group of northern Ethiopia (Negash syncline). Here, a pronounced …
Comments on “Mean velocity and turbulent characteristics of flow over half-cycle cosine sharp-crested weirs” by Salehi S., Esmaili K., Azimi A.H.
2019
Abstract In this paper the stage-discharge equation of a half-cycle cosine weir is theoretically deduced applying the Π-Theorem of dimensional analysis and the self-similarity theory. The coefficients of the new stage-discharge relationships are estimated using the results of the experimental runs by Salehi et al..