Search results for "derived"

Generalized twisted cubics on a cubic fourfold as a moduli space of stable objects

2016

We revisit the work of Lehn-Lehn-Sorger-van Straten on twisted cubic curves in a cubic fourfold not containing a plane in terms of moduli spaces. We show that the blow-up $Z'$ along the cubic of the irreducible holomorphic symplectic eightfold $Z$, described by the four authors, is isomorphic to an irreducible component of a moduli space of Gieseker stable torsion sheaves or rank three torsion free sheaves. For a very general such cubic fourfold, we show that $Z$ is isomorphic to a connected component of a moduli space of tilt-stable objects in the derived category and to a moduli space of Bridgeland stable objects in the Kuznetsov component. Moreover, the contraction between $Z'$ and $Z$ i…

Translocation of cdk2 to the nucleus during G1-phase in PDGF-stimulated human fibroblasts.

1997

We studied the subcellular distribution of cdk2 in synchronized, PDGF-stimulated human fibroblasts (FH109). After contact inhibition and serum depletion, more than 95% of FH109 cells were arrested in G0/G1-phase. PDGF-AB led to a 16-fold increase in proliferation compared with untreated cells. Cell cycle progression was studied by flow cytometric analysis, [3H]thymidine incorporation, and phosphorylation of the retinoblastoma gene product, pRB. Using Western blot analysis after subcellular fractionation, we revealed that after PDGF stimulation the phosphorylated (Thr 160), i.e., activated, form of cdk2 (33 kDa) first appeared in the nucleus at late G1-phase and persisted throughout until to…

A Partial Equilibrium Model of Option Markets

2000

This paper addresses the questions who is buying and who is selling options on a stock, the optimal position to hold, and how this affects the price. The individual demand functions and the equilibrium allocation are derived using an asymptotically valid expansion. Trading occurs only at discrete dates; the option does not have to complete the market. The paper also discusses the conditions under which trade results, the importance of heterogeneity for trade, when preferences become irrelevant to price options, and the case in which there is only a spanning demand, but no risk-sharing demand in options.

A germline mutation in the platelet-derived growth factor receptor beta gene may be implicated in hereditary progressive mucinous histiocytosis.

2020

New lower bounds for the minimum distance of generalized algebraic geometry codes

2013

Abstract In this paper, we give a new lower bound for generalized algebraic geometry codes with which we are able to construct some new linear codes having better parameters compared with the ones known in the literature. Moreover, we give a relationship between a family of generalized algebraic geometry codes and algebraic geometry codes. Finally, we propose a decoding algorithm for such a family.

Derived categories of irreducible projective curves of arithmetic genus one

2006

We investigate the bounded derived category of coherent sheaves on irreducible singular projective curves of arithmetic genus one. A description of the group of exact auto-equivalences and the set of all $t$ -structures of this category is given. We describe the moduli space of stability conditions, obtain a complete classification of all spherical objects in this category and show that the group of exact auto-equivalences acts transitively on them. Harder–Narasimhan filtrations in the sense of Bridgeland are used as our main technical tool.

Effects of escitalopram on the regulation of brain-derived neurotrophic factor and nerve growth factor protein levels in a rat model of chronic stres…

2009

Escitalopram (ES-CIT) is a widely used, highly specific antidepressant. Until now there has been very little evidence on how this drug under pathological conditions affects an important feature within the pathophysiology of stress-related disorders such as depression: the endogenous neurotrophins. By using a well-characterized rat model in which chronic stress induces depressive-like behavior, the levels of neurotrophins brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) were determined in representative brain regions and serum using a highly sensitive improved fluorometric two-site ELISA system. There was a significant increase of BDNF in the left and right cortices aft…

GDNF reverses priming for dyskinesia in MPTP-treated, L-DOPA-primed common marmosets

2001

Parkinson's disease (PD) is associated with a progressive loss of dopamine neurons in the substantia nigra and degeneration of dopaminergic terminals in the striatum. Although L-DOPA treatment provides the most effective symptomatic relief for PD it does not prevent the progression of the disease, and its long-term use is associated with the onset of dyskinesia. In rodent and primate studies, glial cell line-derived neurotrophic factor (GDNF) may prevent 6-OHDA- or MPTP-induced nigral degeneration and so may be beneficial in the treatment of PD. In this study, we investigate the effects of GDNF on the expression of dyskinesia in L-DOPA-primed MPTP-treated common marmosets, exhibiting dyskin…

Production of Haploid and Doubled Haploid Lines in Nut Crops: Persian Walnut, Almond, and Hazelnut

2021

This chapter deals with induction of haploidy via parthenogenesis in Persian walnut and via microspore embryogenesis in almond and hazelnut. Haploid induction through in situ parthenogenesis using pollination with irradiated pollen to stimulate the embryogenic development of the egg cell, followed by in vitro culture of the immature haploid embryos. Microspore embryogenesis allows the induction of immature pollen grains (microspores), to move away from the normal gametophytic developmental route in the direction of the sporophytic one, yielding homozygous organisms (embryos in this case). Unlike other fruit crops (such as Citrus), regeneration of entire plants has not yet been obtained in o…

Refuse Derived Fuel Gasification Possibilities in Small Scale Units

2018

Fossil fuels use reduction and waste recycling are two great challenges facing our society nowadays. A concept intended to solve both problems is Waste-to-Energy (WtE) approach (Brunner and Rechberger in Waste Manag 37: 3–12, 2015). The routes to the energy recovery can be grouped as thermo-chemical and biochemical approaches and the selection of the WtE technologies also depends on the waste composition. Waste sources can be industrial and agricultural production and urban regions but growing attention is paid to municipal solid waste in OECD countries (Hoornweg and Bhada-Tata in What a waste: a global review of solid waste management. World Bank, Washington, DC 2012) consisting dominantly…