Search results for "likelihood"

showing 10 items of 264 documents

Tests against stationary and explosive alternatives in vector autoregressive models

2008

.  The article proposes new tests for the number of unit roots in vector autoregressive models based on the eigenvalues of the companion matrix. Both stationary and explosive alternatives are considered. The limiting distributions of test statistics depend only on the number of unit roots. Size and power are investigated, and it is found that the new test against some stationary alternatives compares favourably with the widely used likelihood ratio test for the cointegrating rank. The powers are prominently higher against explosive than against stationary alternatives. Some empirical examples are provided to show how to use the new tests with real data.

Statistics and ProbabilityAutoregressive modelExplosive materialRank (linear algebra)Applied MathematicsLikelihood-ratio testCompanion matrixEconometricsUnit rootStatistics Probability and UncertaintyEigenvalues and eigenvectorsMathematicsStatistical hypothesis testingJournal of Time Series Analysis
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Sparse Sampling and Maximum Likelihood Estimation for Boolean Models

1991

A condition for practical independence of contact distribution functions in Boolean models is obtained. This result allows the authors to use maximum likelihcod methods, via sparse sampling, for estimating unknown parameters of an isotropic Boolean model. The second part of this paper is devoted to a simulation study of the proposed method. AMS classification: 60D05

Statistics and ProbabilityBiometricsBoolean modelIsotropySampling (statistics)General MedicineLikelihood-ratio testStatisticsMaximum satisfiability problemStatistics Probability and UncertaintyAlgorithmIndependence (probability theory)Standard Boolean modelMathematicsBiometrical Journal
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A Unified Approach to Likelihood Inference on Stochastic Orderings in a Nonparametric Context

1998

Abstract For data in a two-way contingency table with ordered margins, we consider various hypotheses of stochastic orders among the conditional distributions considered by rows and show that each is equivalent to requiring that an invertible transformation of the vectors of conditional row probabilities satisfies an appropriate set of linear inequalities. This leads to the construction of a general algorithm for maximum likelihood estimation under multinomial sampling and provides a simple framework for deriving the asymptotic distribution of log-likelihood ratio tests. The usual stochastic ordering and the so called uniform and likelihood ratio orderings are considered as special cases. I…

Statistics and ProbabilityCombinatoricsIndependent and identically distributed random variablesLinear inequalityTransformation (function)Likelihood-ratio testAsymptotic distributionApplied mathematicsConditional probability distributionStatistics Probability and UncertaintyStochastic orderingStatistical hypothesis testingMathematicsJournal of the American Statistical Association
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On Rao Score and Pearson X2 Statistics in Generalized Linear Models

2005

The identity of the Rao score and PearsonX 2 statistics is well known in the areas where the latter was first introduced: goodness-of-fit in contingency tables and binary responses. We show in this paper that the same identity holds when the two statistics are used for testing goodness-of-fit of Generalized Linear Models. We also highlight the connections that exist between the two statistics when they are used for the comparison of nested models. Finally, we discuss some merits of these unifying results.

Statistics and ProbabilityContingency tableProper linear modelstatisticLinear modelScoreRao scoreGeneralized linear mixed modelHierarchical generalized linear modelQuasi-likelihoodStatisticsStatistics Probability and Uncertaintylinear modelsGeneralized estimating equationMathematics
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MLML2R: an R package for maximum likelihood estimation of DNA methylation and hydroxymethylation proportions.

2019

Abstract Accurately measuring epigenetic marks such as 5-methylcytosine (5-mC) and 5-hydroxymethylcytosine (5-hmC) at the single-nucleotide level, requires combining data from DNA processing methods including traditional (BS), oxidative (oxBS) or Tet-Assisted (TAB) bisulfite conversion. We introduce the R package MLML2R, which provides maximum likelihood estimates (MLE) of 5-mC and 5-hmC proportions. While all other available R packages provide 5-mC and 5-hmC MLEs only for the oxBS+BS combination, MLML2R also provides MLE for TAB combinations. For combinations of any two of the methods, we derived the pool-adjacent-violators algorithm (PAVA) exact constrained MLE in analytical form. For the…

Statistics and ProbabilityDNA HydroxymethylationEpigenomicsIterative methodMaximum likelihood03 medical and health sciencessymbols.namesake0302 clinical medicineGeneticsHumansMolecular Biology030304 developmental biologyMathematics0303 health sciencesLikelihood FunctionsComputational BiologyHigh-Throughput Nucleotide SequencingProbability and statisticsDNA MethylationComputational MathematicsR packageLagrange multiplierDNA methylationsymbolsIterative approximationAlgorithm030217 neurology & neurosurgeryStatistical applications in genetics and molecular biology
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Modeling temperature effects on mortality: multiple segmented relationships with common break points.

2008

We present a model for estimation of temperature effects on mortality that is able to capture jointly the typical features of every temperature-death relationship, that is, nonlinearity and delayed effect of cold and heat over a few days. Using a segmented approximation along with a doubly penalized spline-based distributed lag parameterization, estimates and relevant standard errors of the cold- and heat-related risks and the heat tolerance are provided. The model is applied to data from Milano, Italy.

Statistics and ProbabilityDistributed lagHot TemperatureTime FactorsInjury controlPoison controltemperature effectRisk FactorsStatisticsHumansSegmented regressionMortalitysegmented regressionWeatherSimulationMathematicsLikelihood FunctionsModels StatisticalTemperatureGeneral MedicineHeat toleranceCold TemperatureSpline (mathematics)Nonlinear systemStandard errorItalyNonlinear DynamicsLinear ModelsRegression AnalysisStatistics Probability and Uncertaintybreak pointSettore SECS-S/01 - StatisticaAlgorithmsBiostatistics (Oxford, England)
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Local Spatial Log-Gaussian Cox Processes for seismic data

2022

AbstractIn this paper, we propose the use of advanced and flexible statistical models to describe the spatial displacement of earthquake data. The paper aims to account for the external geological information in the description of complex seismic point processes, through the estimation of models with space varying parameters. A local version of the Log-Gaussian Cox processes (LGCP) is introduced and applied for the first time, exploiting the inferential tools in Baddeley (Spat Stat 22:261–295, 2017), estimating the model by the local Palm likelihood. We provide methods and approaches accounting for the interaction among points, typically described by LGCP models through the estimation of th…

Statistics and ProbabilityEconomics and Econometricsspatial point processeApplied MathematicsModeling and SimulationLog-Gaussian Cox procelocal composite likelihoodPalm likelihoodseismologySettore SECS-S/01 - StatisticaSocial Sciences (miscellaneous)Analysis
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Tailoring sparse multivariable regression techniques for prognostic single-nucleotide polymorphism signatures.

2011

When seeking prognostic information for patients, modern technologies provide a huge amount of genomic measurements as a starting point. For single-nucleotide polymorphisms (SNPs), there may be more than one million covariates that need to be simultaneously considered with respect to a clinical endpoint. Although the underlying biological problem cannot be solved on the basis of clinical cohorts of only modest size, some important SNPs might still be identified. Sparse multivariable regression techniques have recently become available for automatically identifying prognostic molecular signatures that comprise relatively few covariates and provide reasonable prediction performance. For illus…

Statistics and ProbabilityEpidemiologyComputer scienceFeature selectionBiostatisticscomputer.software_genrePolymorphism Single NucleotideLasso (statistics)Gene FrequencyResamplingCovariateHumansLikelihood FunctionsModels StatisticalMultivariable calculusRegression analysisGenomicsPrognosisRegressionMinor allele frequencyLeukemia Myeloid AcuteMultivariate AnalysisRegression AnalysisData miningcomputerAlgorithmsStatistics in medicine
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Maximum likelihood estimation for the exponential power function parameters

1995

This paper addresses the problem of obtaining maximum likelihood estimates for the three parameters of the exponential power function; the information matrix is derived and the covariance matrix is here presented; the regularity conditions which ensure asymptotic normality and efficiency are examined. A numerical investigation is performed for exploring the bias and variance of the maximum likelihood estimates and their dependence on sample size and shape parameter.

Statistics and ProbabilityEstimation theoryRestricted maximum likelihoodMaximum likelihood sequence estimationLikelihood principlesymbols.namesakeEstimation of covariance matricesModeling and SimulationStatisticsExpectation–maximization algorithmsymbolsFisher informationLikelihood functionMathematicsCommunications in Statistics - Simulation and Computation
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dglars: An R Package to Estimate Sparse Generalized Linear Models

2014

dglars is a publicly available R package that implements the method proposed in Augugliaro, Mineo, and Wit (2013), developed to study the sparse structure of a generalized linear model. This method, called dgLARS, is based on a differential geometrical extension of the least angle regression method proposed in Efron, Hastie, Johnstone, and Tibshirani (2004). The core of the dglars package consists of two algorithms implemented in Fortran 90 to efficiently compute the solution curve: a predictor-corrector algorithm, proposed in Augugliaro et al. (2013), and a cyclic coordinate descent algorithm, proposed in Augugliaro, Mineo, and Wit (2012). The latter algorithm, as shown here, is significan…

Statistics and ProbabilityGeneralized linear modelEXPRESSIONMathematical optimizationTISSUESFortrancyclic coordinate descent algorithmdgLARSFeature selectionDANTZIG SELECTORpredictor-corrector algorithmLIKELIHOODLEAST ANGLE REGRESSIONsparse modelsDifferential (infinitesimal)differential geometrylcsh:Statisticslcsh:HA1-4737computer.programming_languageMathematicsLeast-angle regressionExtension (predicate logic)Expression (computer science)generalized linear modelsBREAST-CANCER RISKVARIABLE SELECTIONDifferential geometrydifferential geometry generalized linear models dgLARS predictor-corrector algorithm cyclic coordinate descent algorithm sparse models variable selection.MARKERSHRINKAGEStatistics Probability and UncertaintyHAPLOTYPESSettore SECS-S/01 - StatisticacomputerAlgorithmSoftware
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