Search results for "locu"
showing 10 items of 751 documents
Up-to-date report on the distribution ofHelianthemum lippii(Cistaceae) in Italy
2015
An up-to-date report on the distribution of Helianthemum lippii in Italy is provided also on the basis of the findings by Lojacono-Pojero in 1889 who reported the existence of a relic population in Sicily (southern Italy), which is now thought to be extinct because of human disturbance. Field excursions permitted to confirm the locus classicus reported by Lojacono-Pojero as the other Sicilian localities that have been reported more recently. Based on a careful analysis of the literature the presence of H. lippii is currently excluded in Calabria and Apulia. The main causes that threaten the habitat of H. lippii in Sicily are pointed out according to IUCN Threats Classification Scheme.
Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium.
2012
Myopia is a complex genetic disorder and a common cause of visual impairment among working age adults. Genome-wide association studies have identified susceptibility loci on chromosomes 15q14 and 15q25 in Caucasian populations of European ancestry. Here, we present a confirmation and meta-analysis study in which we assessed whether these two loci are also associated with myopia in other populations. The study population comprised 31 cohorts from the Consortium of Refractive Error and Myopia (CREAM) representing 4 different continents with 55,177 individuals; 42,845 Caucasians and 12,332 Asians. We performed a meta-analysis of 14 single nucleotide polymorphisms (SNPs) on 15q14 and 5 SNPs on …
Population structure and reticulate evolution of Saccharomyces eubayanus and its lager-brewing hybrids
2014
Reticulate evolution can be a major driver of diversification into new niches, especially in disturbed habitats and at the edges of ranges. Industrial fermentation strains of yeast provide a window into these processes, but progress has been hampered by a limited understanding of the natural diversity and distribution of Saccharomyces species and populations. For example, lager beer is brewed with Saccharomyces pastorianus, an alloploid hybrid of S. cerevisiae and S. eubayanus, a species only recently discovered in Patagonia, Argentina. Here, we report that genetically diverse strains of S. eubayanus are readily isolated from Patagonia, demonstrating that the species is well established the…
The implicit in "In search of lost ime" : study on an aspect of proustien speech
2013
The implicit is defined as content present in speech without being formally expressed. Presupposition and implied content are the two fundamental elements of this concept. They act as information implied in speech whose essence the speaker can grasp or decrypt using the theories of pragmatics and enunciative linguistics. Proustian speech constitutes a remarkable example of the use of the implicit and its concepts. The present work is entirely devoted to the search for the implicit in Proust’s In Search of Lost Time. In our work, the development of this concept emerges especially in the verbal interaction between Proust's characters, also, through the speech of the narrator who opts for a ne…
Phylogenetic relationship among genera of Polymorphidae (Acanthocephala), inferred from nuclear and mitochondrial gene sequences.
2013
Abstract Acanthocephalans of the family Polymorphidae Meyer, 1931 are obligate endoparasites with complex life cycles. These worms use vertebrates (marine mammals, fish-eating birds and waterfowl) as definitive hosts and invertebrates (amphipods, decapods and euphausiids) as intermediate hosts to complete their life cycle. Polymorphidae has a wordwide distribution, containing 12 genera, with approximately 127 species. The family is diagnosed by having a spinose trunk, bulbose proboscis, double-walled proboscis receptacle, and usually four to eight tubular cement glands. To conduct a phylogenetic analysis, in the current study sequences of the small (18S) and large-subunit (28S) ribosomal RN…
Whole exome sequencing and system biology analysis support the "two-hit" mechanism in the onset of Ameloblastoma
2021
Background Ameloblastoma is the most frequent odontogenic tumor. Various evidence has highlighted the role of somatic mutations, including recurrent mutation BRAF V600E, in the tumorigenesis of Ameloblastoma, but the intact genetic pathology remains unknown. Material and Methods We sequenced the whole exome of both tumor tissue and healthy bone tissue from four mandibular ameloblastoma patients. The identified somatic mutations were integrated into Weighted Gene Co-expression Network Analysis on publicly available expression data of odontoblast, ameloblast, and Ameloblastoma. Results We identified a total of 70 rare and severe somatic mutations. We found BRAF V600E on all four patients, sup…
Null alleles of human complement C4. Evidence for pseudogenes at the C4A locus and for gene conversion at the C4B locus
1990
The two genes for the C4A and C4B isotypes of the fourth component of human complement are located in the MHC class III region. Previous studies have demonstrated the unusual expression of C4 genes in the form of aberrant or duplicated haplotypes. Null alleles of C4A or C4B (AQ0 or BQ0) have been defined by the absence of gene products and occur at frequencies of 0.1-0.3. However, only some C4 null alleles are due to gene deletions, the remainder were thought to be nonexpressed genes. We have analyzed the C4 gene structure of 26 individuals lacking either C4A or C4B protein. The DNA of individuals with apparently nonexpressed C4 genes was tested for the presence of C4A- and C4B-specific seq…
Perceived Vulnerability to Disease Questionnaire: Factor structure, psychometric properties and gender differences
2016
Abstract The evolutionary psychological approach links evolved mechanisms of disease-avoidance to prejudices against individuals perceived as a threat to health. Perceived vulnerability to disease works as an adaptive strategy which explains why individuals perceived as a source of contagion are avoided. The self-report Perceived Vulnerability to Disease Questionnaire, PVDQ, is one of the most widely used to measure subjective vulnerability to disease, however, neither test–retest reliability has been studied nor has factor structure been confirmed so far in this questionnaire. In the present study, a sample of 878 participants completed the PVDQ. Subsamples also completed different scales …
On the Oort conjecture for Shimura varieties of unitary and orthogonal types
2014
In this paper we study the Oort conjecture on Shimura subvarieties contained generically in the Torelli locus in the Siegel modular variety $\mathcal{A}_g$. Using the poly-stability of Higgs bundles on curves and the slope inequality of Xiao on fibred surfaces, we show that a Shimura curve $C$ is not contained generically in the Torelli locus if its canonical Higgs bundles contains a unitary Higgs subbundle of rank at least $(4g+2)/5$. From this we prove that a Shimura subvariety of $\mathbf{SU}(n,1)$-type is not contained generically in the Torelli locus when a numerical inequality holds, which involves the genus $g$, the dimension $n+1$, the degree $2d$ of CM field of the Hermitian space,…
La singularité de O’Grady
2006
Let M 2 v M_{2v} be the moduli space of semistable sheaves with Mukai vector 2 v 2v on an abelian or K 3 K3 surface where v v is primitive such that ⟨ v , v ⟩ = 2 \langle v,v \rangle =2 . We show that the blow-up of the reduced singular locus of M 2 v M_{2v} provides a symplectic resolution of singularities. This provides a direct description of O’Grady’s resolutions of M K 3 ( 2 , 0 , 4 ) M_{K3}(2,0,4) and M A b ( 2 , 0 , 2 ) M_{Ab}(2,0,2) . Résumé. Soit M 2 v M_{2v} l’espace de modules des faisceaux semi-stables de vecteur de Mukai 2 v 2v sur une surface K 3 K3 ou abélienne où v v est primitif tel que ⟨ v , v ⟩ = 2 \langle v,v \rangle =2 . Nous montrons que l’éclatement de M 2 v M_{2v} le…