Search results for "msu"

Zvaigžņotā Debess: 2018, Pavasaris (239)

2018

Contents: “ZVAIGŽŅOTĀ DEBESS” FORTY YEARS AGO: A.Balklavs. Some Considerations about Communication with Extraterrestrial Civilizations (abridged) ; I.Rabinovičs. Does the Moon Affect Living Nature? (abridged) ; DEVELOPMENTS in SCIENCE: K.Schwartz. Brown Dwarfs ; DISCOVERIES: I.Pundure. Odd Movements of Star Reveal Lonely Black Hole in Globular Star Cluster ; I.Pundure. Gaia Enables Viewing Evolution of Orion Constellation over Coming 450 000 Years ; J.Kuzmanis. A Guest from Another Stars ; SPACE RESEARCH and EXPLORATION: J.Jaunbergs. To Catch the Galactic Visitor `Oumuamua ; J.Jaunbergs. Invisible Connections of Dione ; LATVIAN SCIENTISTS: The List of Popular Science Papers (1958-2016) by P…

Zvaigžņotā Debess: 2006, Vasara

2006

Latvijas Zinātnes padome, Latvijas Universitāte

Cardiovascular and ocular safety of α1-adrenoceptor antagonists in the treatment of male lower urinary tract symptoms

2014

α1-Adrenoceptor antagonists (α-blockers) represent first-line drug treatment for male lower urinary tract symptoms. Their adverse events (AEs) include asthenia, dizziness, nasal congestion, arterial (orthostatic) hypotension and intraoperative floppy iris syndrome (IFIS).This report focuses on cardiovascular and ocular AEs of α-blockers as related to their mechanism of action and subtype selectivity.The incidence of hypotension differs between α-blockers. It is greatest with doxazosin or terazosin, but others including tamsulosin can also lead to hypotension especially upon treatment initiation. Concomitant antihypertensive medication increases the incidence of hypotension with some α-block…

Re: Tamsulosin and the Risk of Dementia in Older Men with Benign Prostatic Hyperplasia.

2018

Pharmacologic pupil dilation as a predictive test for the risk for intraoperative floppy-iris syndrome.

2011

PURPOSE: To evaluate the effect of α1-adrenergic receptor antagonists (α1-ARAs) on pupil diameter and determine whether the diameter predicts intraoperative floppy-iris syndrome (IFIS). SETTING: Ophthalmology Section, Palermo University, Palermo, Italy. DESIGN: Prospective cohort study. METHODS: Male outpatients taking tamsulosin, α(1)-ARAs, or no α(1)-ARAs having phacoemulsification were recruited. Pupils were measured 1 month preoperatively, immediately preoperatively, and postoperatively under mesopic low (0.4 lux) and high (4.0 lux) illumination after pharmacologic dilation. The IFIS severity was graded. RESULTS: Each group comprised 50 patients. Pharmacologic dilation in both α(1)-ARA …

Cognitive and mood side effects of lower urinary tract medication

2019

Introduction: Muscarinic receptor antagonists, 5α-reductase inhibitors and α1-adrenoceptor antagonists are frequently used drug classes for the treatment of lower urinary tract symptoms including those of overactive bladder syndrome and benign prostatic enlargement/benign prostatic obstruction. Areas covered: The authors review the evidence for adverse effects of these drug classes on cognitive function, mood and other functions of the central nervous system and discuss such effects against the evidence for mechanistic plausibility. Expert opinion: Muscarinic antagonists carry a risk for impaired cognition and other brain functions that differs quantitatively between compounds, being highes…

Model‐based meta‐analysis of the time to first acute urinary retention or benign prostatic hyperplasia‐related surgery in patients with moderate or s…

2021

Aims Combination therapy of 5α‐reductase inhibitor and α‐blocker is a guideline‐endorsed therapeutic approach for patients with moderate‐to‐severe lower urinary tract symptoms or benign prostatic hyperplasia (LUTS/BPH) who are at risk of disease progression. We aimed to disentangle the contribution of clinical and demographic baseline characteristics affecting the risk of acute urinary retention or BPH‐related surgery (AUR/S) from the effect of treatment with drugs showing symptomatic and disease‐modifying properties. Methods A time‐to‐event model was developed using pooled data from patients (n = 10 238) enrolled into six clinical studies receiving placebo, tamsulosin, dutasteride or tamsu…

If you drink, don't smoke : Joint associations between risky health behaviors and labor market outcomes

2018

This paper examines the links between risky health behaviors and labor market success. We provide new evidence on the joint relationships between the most prominent forms of risky health behavior - alcohol consumption, smoking and physical inactivity - and long-term labor market outcomes. We use twin data for Finnish men and women linked to register-based individual information on earnings and labor market attachment. The twin data allow us to account for shared family and environmental factors and to measure risky health behaviors in 1975 and 1981. The long-term labor market outcomes were measured in adulthood as an average over the period 1990-2009. The sample sizes are 2156 and 2498 twin…

Zvaigžņotā Debess: 2010, Vasara (208)

2010

Contents: N.Cimahoviča. Sun’s Researcher in the Far East ; A.Balklavs. A New Hypothesis on Formation of Galaxies ; A.Balklavs. Gravitation and Peculiar Galaxies ; A.Barzdis. First Population Stars and Galaxies ; Z.Alksne, A.Alksnis. Does Giant Planet Orbit Dwarf Star? ; A.Alksnis, Z.Alksne. Epsilon Aurigae Eclipsed by Dark Dust Disk ; M.Ābele, K.Adgere, E.Grabs, L.Osipova, E.Rutkovska, J.Vjaters, V.Veckalns. Latvian Students Take Part in the Project European Student Moon Orbiter ; Announcement on the 3rd International Symposium on Dark-Sky Parks: 6-10 September 2010, Croatia ; J.Jansons. Vladimir Afanasjev – Officer of the Baikonur Cosmodrom in the 1970s ; J.Limansky. The International Year…

Traffic simulation models calibration using speed–density relationship: An automated procedure based on genetic algorithm

2016

Calibration of traffic models.Calibration as optimization problem.Use of genetic algorithm. This paper presents the first results of a research which applied a genetic algorithm to calibrate a microscopic traffic simulation model based on speed-density relationships. A large set of traffic data collected from the A22 Freeway, Italy, was used and a comparison was performed between the field measurements and the simulation outputs obtained for a test freeway segment by using the Aimsun microscopic simulator.The calibration was formulated as an optimization problem to be solved based on a genetic algorithm; the objective function was defined in order to minimize the differences between the sim…