Search results for "nuclear medicine"

showing 10 items of 3573 documents

Pregnancy Outcome in Maternal Crigler-Najjar Syndrome Type II: A Case Report and Systematic Review of the Literature

2008

<i>Objective:</i> To report a case of maternal Crigler-Najjar syndrome (CNS) type II in pregnancy, systematically review the literature for similar case reports, and to evaluate whether pregnancy is safe in patients with the disease. Data sources included the PubMed and uptodate databases. <i>Results:</i> A 37-year-old mother with CNS type II was treated with phenobarbital during her pregnancy and her bilirubin levels were monitored. Her newborn had mild direct hyperbilirubinemia, did not require any treatment and his postnatal follow-up showed normal growth and development as well as normal hearing. <i>Conclusion:</i> CNS type II is rare, and only a few …

AdultMaleEmbryologyPediatricsmedicine.medical_specialtyBilirubinCrigler–Najjar syndromeDiseasechemistry.chemical_compoundPregnancymedicineHumansRadiology Nuclear Medicine and imagingNeonatologyHearing DisordersKernicterusCrigler-Najjar SyndromePregnancyFetusbusiness.industryInfant NewbornPregnancy OutcomeInfantObstetrics and GynecologyBilirubinGeneral Medicinemedicine.diseaseSurgeryPregnancy ComplicationschemistryPhenobarbitalPediatrics Perinatology and Child HealthGestationFemalePhenobarbitalbusinessmedicine.drugFetal Diagnosis and Therapy
researchProduct

Estimated radiation exposure of German commercial airline cabin crew in the years 1960-2003 modeled using dose registry data for 2004-2015.

2016

Exposure to ionizing radiation of cosmic origin is an occupational risk factor in commercial aircrew. In a historic cohort of 26,774 German aircrew, radiation exposure was previously estimated only for cockpit crew using a job-exposure matrix (JEM). Here, a new method for retrospectively estimating cabin crew dose is developed. The German Federal Radiation Registry (SSR) documents individual monthly effective doses for all aircrew. SSR-provided doses on 12,941 aircrew from 2004 to 2015 were used to model cabin crew dose as a function of age, sex, job category, solar activity, and male pilots' dose; the mean annual effective dose was 2.25 mSv (range 0.01–6.39 mSv). In addition to an inverse …

AdultMaleEngineeringOperations researchAircraftOccupational riskMean squared prediction errorCrewToxicologyRadiation DosageEffective dose (radiation)Risk Assessment030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineAge DistributionAeronauticsOccupational ExposureRadiation IonizingHumansRegistriesSex DistributionRetrospective Studiesbusiness.industryPublic Health Environmental and Occupational Healthjob-exposure matrixexposure modelingMiddle AgedRadiation Exposure030210 environmental & occupational healthPollutionRadiation exposurePilotsCohortaviationAircrewRegistry dataepidemiologyFemalebusinessionizing radiationCosmic RadiationEnvironmental MonitoringJournal of exposure scienceenvironmental epidemiology
researchProduct

Mini-Laparoscopically Guided Percutaneous Gastrostomy and Jejunostomy

2003

Abstract Background: Percutaneous endoscopic tube placement can be problematic under certain circumstances: absence of transillumination of the abdominal wall, percutaneous jejunostomy in patients with a PEG tube and recurrent aspiration, enteral feeding access after gastrectomy, and obstruction of the upper GI tract. As an alternative in these problematic situations, a technique was developed for placing feeding tubes under visual control by using mini-laparoscopy. Methods: Placement of a feeding tube with mini-laparoscopy with the patient under conscious sedation was considered for 17 patients in whom standard PEG placement was impossible. Techniques used were the following: combined mini…

AdultMaleEnteroscopymedicine.medical_specialtyPercutaneousmedicine.medical_treatmentConscious SedationJejunostomyEnteral NutritionmedicineHumansIntubationRadiology Nuclear Medicine and imagingIntubation GastrointestinalFeeding tubeAgedGastrostomymedicine.diagnostic_testbusiness.industryGastroenterologyMiddle AgedGastrostomySurgeryEndoscopyJejunostomyFemaleLaparoscopybusinessPercutaneous Endoscopic TubeGastrointestinal Endoscopy
researchProduct

Double-balloon enteroscopy (push-and-pull enteroscopy) of the small bowel: feasibility and diagnostic and therapeutic yield in patients with suspecte…

2005

Background Double-balloon enteroscopy (push-and-pull enteroscopy) is a new method that allows complete visualization, biopsy, and treatment in the small bowel. This study evaluated the feasibility and the diagnostic and the therapeutic yield of double-balloon enteroscopy (push-and-pull enteroscopy) in comparison with current imaging methods. Methods Between March 2003 and November 2004, 248 consecutive double-balloon enteroscopies (push-and-pull enteroscopies) were performed in a prospective study in 137 patients with suspected small-bowel disease (60 women, 77 men; mean age 56.6 ± 17.8 years), most with chronic GI bleeding (66%). The examinations were carried out after negative evaluations…

AdultMaleEnteroscopymedicine.medical_specialtymedicine.medical_treatmentEndoscopy GastrointestinalDiagnosis DifferentialDouble-balloon enteroscopyIntestine SmallBiopsymedicineHumansRadiology Nuclear Medicine and imagingProspective StudiesAngiodysplasiaProspective cohort studyAgedAged 80 and overmedicine.diagnostic_testbusiness.industryGastroenterologySingle-Balloon EnteroscopyEquipment DesignMiddle Agedmedicine.diseaseSurgeryEndoscopyEndoscopes GastrointestinalIntestinal DiseasesTherapeutic endoscopyFeasibility StudiesFemaleRadiologybusinessFollow-Up StudiesGastrointestinal Endoscopy
researchProduct

Decreased dopamine D2/D3-receptor binding in temporal lobe epilepsy: an [18F]fallypride PET study.

2006

Summary: Purpose: Although animal data are suggestive, evidence for an alteration of the extrastriatal dopaminergic system in human focal epilepsy is missing. Methods: To quantify D2/D3-receptor density, we studied seven patients with temporal lobe epilepsy (TLE) and nine agematched controls with positron emission tomography (PET) by using the high-affinity dopamine D2/D3-receptor ligand [ 18 F]Fallypride ([ 18 F]FP) suitable for imaging extrastriatal binding. TLE was defined by interictal and ictal video-EEG, magnetic resonance imaging (MRI), and [ 18 F]fluorodeoxyglucose ([ 18 F]FDG)-PET and was due to hippocampal sclerosis (HS), based on histology in all patients. Primary analysis was ba…

AdultMaleFluorine RadioisotopesPyrrolidinesHippocampusHippocampal formationHippocampusFunctional LateralityTemporal lobeAnimal dataFluorodeoxyglucose F18medicineHumansTissue DistributionFluorodeoxyglucoseHippocampal sclerosisBrain MappingSclerosisbusiness.industryReceptors Dopamine D2Receptors Dopamine D3Videotape RecordingElectroencephalographymedicine.diseaseMagnetic Resonance ImagingTemporal Lobenervous systemNeurologyFallyprideEpilepsy Temporal LobePositron-Emission TomographyCardiovascular agentBenzamidesNeurology (clinical)Nuclear medicinebusinessmedicine.drugEpilepsia
researchProduct

Automatic fuzzy classification of the washout curves from magnetic resonance first-pass perfusion imaging after myocardial infarction.

2005

International audience; Abstract: Objectives: We sought to investigate the diagnostic ability of cardiac magnetic resonance imaging (MRI) perfusion in acute reper-fused myocardial infarction. The study used fuzzy logic to automatically classify signal intensity-time curves from myocardial segments into 3 categories: normal, hypointense, and Hyperintense. Materials and Methods: Thirty-eight patients with myocardial infarction underwent short-axis cine-MRI and contrast-enhanced MRI to provide data on wall thickening and the transmural extent of infarction. Of these, 17 had a second cardiac MRI to ascertain the functional recovery in each segment. Results: The fuzzy logic based classification …

AdultMaleFuzzy classificationfunctional recoveryMyocardial InfarctionContrast MediaMagnetic Resonance Imaging CineMyocardial Reperfusion030204 cardiovascular system & hematologyFuzzy logicStatistics Nonparametric030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineFuzzy Logicdelayed imagingCardiac magnetic resonance imagingPredictive Value of Tests[INFO.INFO-IM]Computer Science [cs]/Medical ImagingmedicineImage Processing Computer-Assistedmagnetic resonance imagingHumansRadiology Nuclear Medicine and imagingMyocardial infarctionProspective StudiesAgedAged 80 and over[ INFO.INFO-IM ] Computer Science [cs]/Medical Imagingmedicine.diagnostic_testbusiness.industrycontrast-enhanced first-passWashoutMagnetic resonance imagingGeneral MedicineMiddle Agedmedicine.diseasePrognosisFirst pass perfusionFemaleNuclear medicinebusinessPerfusionInvestigative radiology
researchProduct

MR imaging of the heart in patients after myocardial infarction: effect of increasing intersection gap on measurements of left ventricular volume, ej…

1999

International audience; Abstract: PURPOSE: To determine the extent to which the number of planes imaged at magnetic resonance (MR) imaging could be reduced without modifying the volume and thickness of the left ventricle. MATERIALS AND METHODS: Sixty-one patients were examined after a myocardial infarction. The whole left ventricle was imaged by using 5-mm contiguous breath-hold cine MR short-axis sections with no gap (SA(ng)) (two-dimensional fast low-angle shot sequence, 9/4.8 [repetition time msec/echo time msec]). The effect of omitting in two (short-axis sections with 5-mm gap [SA(5mm)]) or two sections in three(short-axis sections with 10-mm gap [SA(10mm)]) was studied. RESULTS: In th…

AdultMaleHeart Ventriclesvolume measurementinfarction[INFO.INFO-IM] Computer Science [cs]/Medical ImagingMyocardial InfarctionInfarctionheart030204 cardiovascular system & hematologyIntersection (Euclidean geometry)030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicinemedicine[INFO.INFO-IM]Computer Science [cs]/Medical ImagingHumansRadiology Nuclear Medicine and imagingMyocardial infarctionejection fractionAgedAged 80 and overvolumeEjection fractionmedicine.diagnostic_test[ INFO.INFO-IM ] Computer Science [cs]/Medical Imagingbusiness.industryventriclesMyocardiumMagnetic resonance imagingStroke VolumeStroke volumeMRMiddle Agedmedicine.diseaseMagnetic Resonance Imagingmedicine.anatomical_structureVentricleEnd-diastolic volumeFemalebusinessNuclear medicinemagnetic resonance (MR)cine studyRadiology
researchProduct

Accuracy of SWI sequences compared to T2*-weighted gradient echo sequences in the detection of cerebral cavernous malformations in the familial form

2016

Purpose The purpose of this study was to assess the accuracy of susceptibility-weighted imaging (SWI), compared with T2*-weighted gradient echo (GRE) imaging in assessing cerebral cavernous malformations. Materials and methods We retrospectively evaluated 21 patients with a familial form of cavernous malformation. Magnetic resonance (MR) protocol included non-enhanced and contrast-enhanced fast-spin echo (FSE) T1-weighted sequences, FSE T2-weighted sequences, fluid-attenuated inversion-recovery (FLAIR), GRE T2*-weighted and SWI sequences. Images were reviewed in consensus by two expert neuroradiologists to assess the location, number, size and conspicuity of the lesions on T2*-weighted GRE …

AdultMaleHemangioma Cavernous Central Nervous SystemCerebrovascular DiseasesStatistics as TopicSensitivity and SpecificityCerebral cavernous malformations030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineNuclear magnetic resonanceImage Processing Computer-AssistedHumansMedicineRadiology Nuclear Medicine and imagingAgedRetrospective StudiesCerebral cavernous malformationFamilial formEcho-Planar Imagingbusiness.industryimagingSettore MED/37 - NeuroradiologiaT2*-weighted gradient echo sequenceGeneral MedicineMiddle AgedImage EnhancementMagnetic Resonance Imagingdiagnosisusceptibility-weighted imagingSusceptibility weighted imagingFemaleNeurology (clinical)T2 weightedbusiness030217 neurology & neurosurgeryGradient echoThe Neuroradiology Journal
researchProduct

Real-time spatial compound sonography of Achilles tendon in patients with heterozygous familial hypercholesterolaemia and normal physical examination

2007

This study was undertaken to assess the prevalence and ultrasound features of Achilles tendon xanthomas (ATX) in patients with heterozygous familial hypercholesterolemia (HFH) and normal physical examination studied with high-resolution ultrasonography (HRUS) and, secondarily, to evaluate the role of real-time spatial compound sonography (CS) in terms of image quality.Both Achilles tendons of 40 patients with HFH were studied with HRUS and CS. Two experienced radiologists evaluated by consensus the presence of ATX described as (1) tendon thickening and/or (2) focal hypoechoic areas and the quality of images obtained with the two techniques.Ten out of 80 tendons showed thickening (mean: 11.2…

AdultMaleHeterozygotemedicine.medical_specialtyAdolescentPhysical examinationFamilial hypercholesterolemiaAchilles TendonHyperlipoproteinemia Type IIMuscular DiseasesXanthomatosismedicineHumansRadiology Nuclear Medicine and imagingIn patientChildPhysical ExaminationAgedUltrasonographyNeuroradiologyAchilles tendonmedicine.diagnostic_testbusiness.industryUltrasoundInterventional radiologyGeneral MedicineMiddle Agedmedicine.diseaseSurgerySonographymedicine.anatomical_structureFemaleUltrasonographybusinessLa radiologia medica
researchProduct

Posterior tibial tendon dysfunction: Clinical and magnetic resonance imaging findings having histology as reference standard.

2017

Abstract Objective To investigate the correlation between MRI, clinical tests, histopathologic features of posterior tibial tendon (PTT) dysfunction in patients with acquired adult flatfoot deformity surgically treated with medializing calcaneal osteotomy and flexor digitorum longus tendon transposition. Materials and methods Nineteen patients (11 females; age: 46 ± 15 year, range 18–75) were pre-operatively evaluated using the single heel rise (HR) and the first metatarsal rise (FMR) sign tests. Two reviewers graded the PTT tears on a I–III scale and measured the hindfoot valgus angle on the pre-operative MRI of the ankle. The specimens of the removed portion of PTT were histologically ana…

AdultMaleHistologyHeelAdolescentIntraclass correlationmedicine.medical_treatmentOsteotomyPreoperative care030218 nuclear medicine & medical imagingTendons03 medical and health sciencesYoung Adult0302 clinical medicineRetrospective StudiePreoperative CaremedicineHumansRadiology Nuclear Medicine and imagingPosterior Tibial Tendon DysfunctionTendonAgedRetrospective Studies030222 orthopedicsmedicine.diagnostic_testbusiness.industryFootMagnetic resonance imagingGeneral MedicineMiddle AgedReference Standardsmedicine.diseaseSingle heel riseFlatfootMagnetic Resonance ImagingOsteotomymedicine.anatomical_structureTendinopathyReference StandardFemaleHindfoot valguFirst metatarsal rise signTendinopathyAnklebusinessNuclear medicinePosterior Tibial Tendon DysfunctionHumanEuropean journal of radiology
researchProduct