Search results for "rotu"
showing 10 items of 642 documents
Strategie di difesa in risposta a stress in embrioni di riccio di mare: L'embrione di riccio di Paracentrotus lividus come modello sperimentale per l…
2013
Negli ultimi decenni, grazie alle nuove tecnologie e alla maggiore disponibilità di strumenti di ricerca, il campo riguardante lo studio delle strategie di difesa attivate nella risposta a stress, compresi i meccanismi di apoptosi e autofagia, è divenuto molto ampio ed è in continua espansione. Sin dagli albori della Biologia, gli studi condotti sul modello sperimentale di riccio di mare hanno permesso di ottenere conoscenze di base, spesso applicabili ad altri modelli biologici. I dati riportati nel presente libro dovrebbero aiutare a far luce sui meccanismi di difesa che le cellule sono in grado di attivare, in caso di necessità, se esposte a sfavorevoli condizioni ambientali. Le osservaz…
Studies on sea urchin oocytes. II. Synthesis of RNA during oogenesis.
1972
Abstract Isolated oocytes of the sea urchin Paracentrotus lividus actively incorporate 3H-uridine into RNA. Labeled RNA was analysed by sucrose gradient and acrylamide gel electrophoresis following cell fractionation. Much of the radioactivity is incorporated at the nucleolar level in the form of rRNA precursors. The kinetics of maturation of these latter suggests that this occurs at a slower rate than during embryogenesis. Other non-nucleolar RNA classes are also actively labelled and retained in the nucleus for many hours. These results are confirmed by an autoradiographic investigation.
Merkillinen historiassa : perustuu virkaanastujaisluentoon 3.12.2014
2015
A Comprehensive Ultrasonographic Assessment of Pediatric and Adolescent Varicocele Can Improve Surgical Results.
2020
<b><i>Purpose:</i></b> Undetected refluxing venous systems could cause persistence/recurrence of varicoceles in patients undergoing varicocelectomy. Color Doppler ultrasound (CDUS) is an important tool in the diagnosis and follow-up of varicocele, and could be successfully used to detect a venous reflux in the iliac-deferential district, usually involved in the recurrence/persistence of varicocele. <b><i>Materials and Methods:</i></b> We compared 2 historical series of patients treated with Palomo laparoscopic varicocelectomy between 1994 and 2018. In group 1, preoperative scrotal CDUS was obtained, while in group 2, additional inguinal CDUS w…
Topotecan triggers apoptosis in p53-deficient cells by forcing degradation of XIAP and survivin thereby activating caspase-3-mediated Bid cleavage.
2009
The topoisomerase I inhibitor topotecan (TPT) is used in the therapy of different tumors including high-grade gliomas. We previously showed that TPT-induced apoptosis depends on p53 with p53 wild-type (wt) cells being more resistant because of p53-controlled degradation of topoisomerase I. Here, we show that p53-deficient (p53(-/-)) fibroblasts undergo excessive mitochondrial apoptosis featuring H2AX phosphorylation, Bcl-x(L) decline, cytochrome c release, caspase-9/-3/-2 activation, and cleavage of Bid. In wt and apaf-1(-/-) cells, caspase-2 did not become activated and Bid was not cleaved. In addition, p53(-/-) cells cotreated with TPT and caspase-3 inhibitor showed neither caspase-2 acti…
Magnus Henrekson and Mikael Stenkula, eds., Swedish taxation: developments since 1862 (New York: Palgrave Macmillan, 2015. Pp. 334. ISBN 978113747814…
2017
LA RIABILITAZIONE NELLA TENDINOPATIA ROTULEA
2008
Ectoderm restricted expression of the TRIM-containing factor Strim1 directs the migration, aggregation and terminal differentiation of mesenchymal ce…
2011
Expression of MAP1a and MAP1b in the ganglionic eminence and the internal capsule of the human fetal brain.
2001
The expression of microtubule-associated proteins 1a and 1b (MAP1a and 1b) were investigated in two transient structures, the ganglionic eminence (GE) being a prominent part of the telencephalic proliferative zone and the perireticular nucleus (PR) within the internal capsule (IC). Anti-MAP1a immunolabels PR neurons from 18 weeks of gestation (wg) onwards, whereas anti-MAP1b immunolabels long IC fibers between 18 and 22 wg. MAP1b is further present in thalamic fibers that seem to terminate at the medial margin of the GE, in a moderate number of cells of the GE and its medial extension, the gangliothalamic body (GTB). From 26 to 33 wg MAP1b is expressed in short fiber bundles of the IC, a fe…
Constitutive hsp70 is essential to mitosis during early cleavage of Paracentrotus lividus embryos: The blockage of constitutive hsp70 impairs mitosis
1999
Localization of constitutive hsp70 in eggs and early embryos of sea urchin Paracentrotus lividus is shown by means of in situ immunostaining. An accumulation of this protein is shown in the mitotic structures (asters, spindles and centrosomes). Microinjection of anti-hsp70 antibodies into eggs causes impairment of formation of mitotic structures and of cell division. This impairment goes from a complete mitotic block, to irregular mitotic apparatus formation with irregular cleavage, depending upon the antibody concentration. The localization of hsp70 after antibody microinjection is also described. Blockage of mitotic apparatus formation by nocodazole also blocks the concentration of hsp70 …