Search results for "rotu"
showing 10 items of 642 documents
Race, Environment, and Crisis : Hurricane Camille and the Politics of Southern Segregation
2022
In August 1969 Hurricane Camille hit the Mississippi coast. We argue that the disaster caused by the Hurricane was an outcome of the entanglement between human and non-human agents. As a non-human agent, Hurricane Camille thrust the prevailing socio-economic situation in the segregationist South into the spotlight, with all its political and cultural ramifications – much to the annoyance of the local political elite that had long sought to isolate southern politics from civil rights and the desegregation agenda. Consequently, it (re)invigorated and furnished the civil rights movement and the politics defining that era with new arguments and approaches that would have been impossible to dev…
Chemical Composition and Antibacterial Activity of Essential Oils from Different Parts of Bupleurum rotundifolium L.
2012
WOS: 000306925400016
Tasaverostako vallitseva verotusmuoto Suomeen? : tutkimus tasaveron kannattajien ja vastustajien argumentoinnista julkisessa keskustelussa
2008
Apoptotic-like Leishmania exploit the host´s autophagy machinery to reduce T-cell-mediated parasite elimination
2015
Apoptosis is a well-defined cellular process in which a cell dies, characterized by cell shrinkage and DNA fragmentation. In parasites like Leishmania, the process of apoptosis-like cell death has been described. Moreover upon infection, the apoptotic-like population is essential for disease development, in part by silencing host phagocytes. Nevertheless, the exact mechanism of how apoptosis in unicellular organisms may support infectivity remains unclear. Therefore we investigated the fate of apoptotic-like Leishmania parasites in human host macrophages. Our data showed--in contrast to viable parasites--that apoptotic-like parasites enter an LC3(+), autophagy-like compartment. The compartm…
Muutokset maksetuissa henkilöveroissa alueittain Suomessa 2000-luvulla
2020
Maksetut henkilöverot alueittain ja ikäryhmittäin Suomessa 2000-2018
2021
Tarkastelemme henkilöverotuksen kehitystä 2000-luvulla eri maakunnissa ja ikäryhmissä. Nuorimmat (alle 40-vuotiaiden) ikäluokat ovat jääneet vanhempien työikäisten ikäluokkien (yli 40-vuotiaiden) vero- ja siis myös tulokehityksestä jälkeen. Kokonaisuudessaan henkilöverokertymä on kasvanut noin 25 %, ja maakuntien väliset erot ovat vähentyneet merkittävästi vuosina 2000–2018. Nykyisen ajankohtaisen veroproblematiikan kannalta havaittu maakuntien myönteinen kehitys helpottaa maakuntapohjaisen sote-mallin rahoitusta. nonPeerReviewed
Solid phase extraction materials as a key for improving the accuracy of silver nanoparticle characterization with single-particle inductively coupled…
2022
The accurate characterization of silver nanoparticles (Ag NPs) in environmental samples is crucial for understanding the potential impact of these materials on the environment and human health. Single-particle inductively coupled plasma mass spectrometry (spICP-MS) is one of the few techniques available for quantifying NPs at environmentally relevant concentrations. However, the spICP-MS detection of Ag NPs can be interfered with coexisting dissolved analyte causing high background signals, which mask NP signals leading to a significant bias in NP characterization. In this paper, a simple sample pre-treatment procedure for efficient removal of dissolved silver in natural waters is proposed …
In vitro antitumor effects of the cold-water extracts of Mediterranean species of genus Pleurotus (higher Basidiomycetes) on human colon cancer cells
2014
The aim of this study was to evaluate whether the cold-water extracts of Pleurotus eryngii var. ferulae (CWE-Pef) and Pleurotus nebrodensis (CWE-Pn), 2 of the most prized wild and cultivated edible mushrooms, can affect the tumor phenotype of human colon cancer HCT116 cells. Our results showed that treatment with CWE- Pef and CWE-Pn resulted in a significant inhibition of the viability of HCT116 cells and promoted apoptosis, as also demonstrated by the increase of Bax-to-Bcl-2 messenger RNA ratio. Moreover, we observed that both extracts were able to inhibit cell migration and to affect homotypic and heterotypic cell-cell adhesion. It also was found that treatment with CWE-Pef and CWE-Pn ne…
Paracentrin 1, a synthetic antimicrobial peptide from the sea-urchin Paracentrotus lividus, interferes with staphylococcal and Pseudomonas aeruginosa…
2014
The rise of antibiotic-resistance as well as the reduction of investments by pharmaceutical companies in the development of new antibiotics have stimulated the investigation for alternative strategies to conventional antibiotics. Many antimicrobial peptides show a high specificity for prokaryotes and a low toxicity for eukaryotic cells and, due to their mode of action the development of resistance is considered unlikely. We recently characterized an antimicrobial peptide that was called Paracentrin 1 from the 5-kDa peptide fraction from the coelomocyte cytosol of the Paracentrotus lividus. In this study, the chemically synthesized Paracentrin 1, was tested for its antimicrobial and antibiof…
Novel Approaches for Immunosuppression in Graves’ Hyperthyroidism and Associated Orbitopathy
2020
<b><i>Background:</i></b> Both Graves’ hyperthyroidism (GH) and Graves’ orbitopathy (GO) are associated with significant adverse health consequences. All conventional treatment options have limitations regarding efficacy and safety. Most importantly, they do not specifically address the underlying immunological mechanisms. We aim to review the latest development of treatment approaches in these two closely related disorders. <b><i>Summary:</i></b> Immunotherapies of GH have recently demonstrated clinical efficacy in preliminary studies. They include ATX-GD-59, an antigen-specific immunotherapy which restores immune tolerance to the thyrotropin…