Search results for "sanita"
showing 10 items of 855 documents
Vers des systèmes viticoles économes en pesticides
2022
L’utilisation de produits phytosanitaires (cuivre, soufre et produits de synthèses) est à ce jour le moyen de lutte le plus efficace pour garantir une vendange qualitative et quantitative (Pujol, 2017). Face aux préoccupations sociétales croissantes concernant l’impact des pesticides sur l’environnement et la santé, la viticulture se doit pourtant de réduire sa dépendance aux produits phytosanitaires. Une transition agroécologique est ainsi nécessaire et implique de changer les pratiques afin de parvenir à diminuer l’utilisation des produits phytosanitaires. Le réseau DEPHY-Ferme a été créé en 2010 afin d’initier et stimuler cette transition agroécologique et répondre aux enjeux ambitieux i…
Unraveling the Composition of Insecticidal Crystal Proteins in Bacillus thuringiensis: a Proteomics Approach.
2020
ABSTRACT Bacillus thuringiensis (Bt) is the most widely used active ingredient for biological insecticides. The composition of δ-endotoxins (Cry and Cyt proteins) in the parasporal crystal determines the toxicity profile of each Bt strain. However, a reliable method for their identification and quantification has not been available, due to the high sequence identity of the genes that encode the δ-endotoxins and the toxins themselves. Here, we have developed an accurate and reproducible mass spectrometry-based method (liquid chromatography-tandem mass spectrometry-multiple reaction monitoring [LC-MS/MS-MRM]) using isotopically labeled proteotypic peptides for each protein in a particular mix…
A practical protocol for calibration of nutrient removal wastewater treatment models
2011
Activated sludge models can be very useful for designing and managing wastewater treatment plants (WWTPs). However, as with every model, they need to be calibrated for correct and reliable application. Activated sludge model calibration is still a crucial point that needs appropriate guidance. Indeed, although calibration protocols have been developed, the model calibration still represents the main bottleneck to modelling. This paper presents a procedure for the calibration of an activated sludge model based on a comprehensive sensitivity analysis and a novel step-wise Monte Carlo-based calibration of the subset of influential parameters. In the proposed procedure the complex calibration i…
Organizzazione e diritto alla salute, alla prova della regionalizzazione e dell'aziendalizzazione dei servizi sanitari
2018
The contribution proposes an analysis of the effectiveness of the right to health, deepening the evolution of “regionalization” and “privatization of a state-owned company” of the National Health Service, in comparison with the marked regional differences (gaps) in the provision of Essential Levels of Assistance. The author researches the profile of the organization and of the financing of health services which take on a peculiar complexity in the health sector, in which there is the most complex experience of decentralization and also the introduction of fiscal federalism through the application of the requirement and the standard cost. For the purposes of overcoming health inequalities, t…
La Asociación Europea contra la Poliomielitis y los programas europeos de vacunación
2012
La búsqueda de una respuesta europea al problema planteado por los brotes epidémicos de poliomielitis en las décadas centrales del siglo XX, desembocó en la creación de un organismo nuevo, la Asociación Europea contra la Poliomielitis en 1951. Los mecanismos de funcionamiento interno y las conexiones internacionales de dicha Asociación fueron subsidiarios de un determinado contexto socio-político que propiciaba este tipo de consorcios. Como muestra este trabajo, su labor en los dieciocho años de existencia fue decisiva para la articulación y el éxito alcanzado por las políticas sanitarias nacionales de inmunización masiva frente a la enfermedad.
The disease-specific clinical trial network for primary ciliary dyskinesia: PCD-CTN
2022
Primary ciliary dyskinesia; Rare genetic disorder; Lung diseases Discinesia ciliar primaria; Trastorno genético raro; Enfermedades pulmonares Discinesia ciliar primària; Trastorn genètic rar; Malalties pulmonars Primary ciliary dyskinesia (PCD) is a rare genetic disorder characterised by impaired mucociliary clearance leading to irreversible lung damage. In contrast to other rare lung diseases like cystic fibrosis (CF), there are only few clinical trials and limited evidence-based treatments. Management is mainly based on expert opinions and treatment is challenging due to a wide range of clinical manifestations and disease severity. To improve clinical and translational research and facili…
Occurrence of illicit drugs in two wastewater treatment plants in the South of Italy
2017
In this study the occurrence and the behavior of illicit drugs and their metabolites have been investigated for two wastewater treatment plants (WWTPs) (namely, WWTP-1 and WWTP-2) located in Sicily (island of Italy). Samples were analyzed for methamphetamine, cocaine (COC), 3,4-methylenedioxymethamphetamine (MDMA), methadone (METH), 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP), 3,4-methylenedioxy amphetamine (MDA); 3,4-methylenedioxy ethylamphetamine (MDEA), 11-nor-9-carboxy-Î9-tetrahydrocannabinol (THC-COOH) and Benzoylecgonine (BEG). The BEG, COC, MOR and THC-COOH were found at the highest concentration in both WWTPs. The Wastewater-based epidemiology calculation for BEG, COC…
Receiving water quality assessment: comparison between simplified and detailed integrated urban modelling approaches
2010
Urban water quality management often requires use of numerical models allowing the evaluation of the cause–effect relationship between the input(s) (i.e. rainfall, pollutant concentrations on catchment surface and in sewer system) and the resulting water quality response. The conventional approach to the system (i.e. sewer system, wastewater treatment plant and receiving water body), considering each component separately, does not enable optimisation of the whole system. However, recent gains in understanding and modelling make it possible to represent the system as a whole and optimise its overall performance. Indeed, integrated urban drainage modelling is of growing interest for tools to …
Uncertainty in urban stormwater quality modelling: The influence of likelihood measure formulation in the GLUE methodology
2009
In the last years, the attention on integrated analysis of sewer networks, wastewater treatment plants and receiving waters has been growing. However, the common lack of data in the urban water-quality field and the incomplete knowledge regarding the interpretation of the main phenomena taking part in integrated urban water systems draw attention to the necessity of evaluating the reliability of model results. Uncertainty analysis can provide useful hints and information regarding the best model approach to be used by assessing its degrees of significance and reliability. Few studies deal with uncertainty assessment in the integrated urban-drainage field. In order to fill this gap, there ha…
Urban Storm-Water Quality Management: Centralized versus Source Control
2010
The continuous growth of urban areas and the increasing public awareness of the environmental impacts of storm water have raised interest on the quality of the receiving water bodies. In the past two decades, many efforts have been directed at improving urban drainage systems by introducing mitigation measures to limit the negative environmental impacts of storm water. These mitigation measures are generally called best management practices (BMPs), sustainable urban drainage systems, or low impact developments, and they include practices such as infiltration and storage tanks that reduce the peak flow and retain some of the polluting materials. Choosing the best mitigation measure is still …