Search results for "subjects"

Vēsturnieks profesors Dr. iur. Arveds Švābe (1888-1959): biobibliogrāfija

1998

Profesors Jurijs Vedins: personālais bibliogrāfiskais rādītājs

1985

Saturs: Priekšvārds. Latvijas PSR nopelniem bagātais zinātnes darbinieks, filozofijas zinātņu doktors, profesors Jurijs Vedins / P. Laizāns. Profesora J. Vedina publicētie darbi (1955.-1984.). Profesora J. Vedina rediģētie un recenzētie darbi. Profesora J. Vedina vadītās disertācijas. Raksti par profesoru J. Vedinu. Profesora J. Vedina publicēto darbu alfabētiskais rādītājs. Personu rādītājs.

Profesors Pēteris Laizāns: darbu rādītājs

2000

Contributor other: Paukšēna, Diāna

Profesore Ilga Apine: personālais bibliogrāfiskais rādītājs

1988

Saturs: Priekšvārds. Vēstures zinātņu doktore profesore Ilga Apine. Vēstures zinātņu doktores profesores I. Apines publicētie darbi (1952. - 1987.) Vēstures zinātņu doktores profesores I. Apines rediģētie darbi. Vēstures zinātņu doktores profesores I. Apines vadītās disertācijas. Raksti par vēstures zinātņu doktori profesori I. Apini. Vēstures zinātņu doktores profesores I. Apines darbu alfabētiskais radītājs. Personu rādītājs.

Neural network approach to solving fuzzy nonlinear equations using Z-numbers

2020

In this article, the fuzzy property is described by means of the Z-number as the coefficients and variables of the fuzzy equations. This alteration for the fuzzy equation is appropriate for system modeling with Z-number parameters. In this article, the fuzzy equation with Z-number coefficients and variables is tended to be used as the models for the uncertain systems. The modeling issue related to the uncertain system is to obtain the Z-number coefficients and variables of the fuzzy equation. Nevertheless, it is extremely hard to get the Z-number coefficients of the fuzzy equations. In this article, in order to model the uncertain nonlinear systems, a novel structure of the multilayer neura…

SANS (USH1G) regulates pre-mRNA splicing by mediating the intra-nuclear transfer of tri-snRNP complexes

2021

Abstract Splicing is catalyzed by the spliceosome, a compositionally dynamic complex assembled stepwise on pre-mRNA. We reveal links between splicing machinery components and the intrinsically disordered ciliopathy protein SANS. Pathogenic mutations in SANS/USH1G lead to Usher syndrome—the most common cause of deaf-blindness. Previously, SANS was shown to function only in the cytosol and primary cilia. Here, we have uncovered molecular links between SANS and pre-mRNA splicing catalyzed by the spliceosome in the nucleus. We show that SANS is found in Cajal bodies and nuclear speckles, where it interacts with components of spliceosomal sub-complexes such as SF3B1 and the large splicing cofact…

T52. COGNITION, METACOGNITION AND SOCIAL COGNITION AFTER A FIRST EPISODE PSYCHOSIS. PRELIMINARY RESULTS FROM A 5-YEAR-FOLLOW-UP STUDY

2020

Abstract Background Cognitive impairment is considered a core feature of psychotic disorders. Deficits in cognition, metacognition and social cognition have been reported to be correlated, and indeed predictors, of functional outcome or level of disability. Psychotic patients tend to present lower IQ and show impairment in specific cognitive domains, and in social cognition, than controls. Several studies have found deficits in facial emotion recognition (FER) and a higher prevalence of the jumping to conclusions (JTC) reasoning and data gathering biases among psychotic patients, even at time of illness onset, compared to controls. However, the trajectory of this impairment remains unclear.…

S118. TRANSDIAGNOSTIC SYMPTOM DIMENSIONS OF PSYCHOSIS AND THE PREDICTIVE ROLE OF PREMORBID ADJUSTMENT AND COGNITIVE CHARACTERISTICS IN THE MULTINATIO…

2020

Abstract Background A symptom dimension approach may best examine the heterogeneous expression of psychosis. However, whether and how premorbid predisposition and cognitive factors explain phenotypes variation is still debated. This study aimed to test the predictive value of combined cognition and premorbid adjustment on transdiagnostic symptom dimensions in a large sample of people suffering from the first episode of psychosis (FEP). Methods FEP patients were part of the EUGEI study. Psychopathology was rated using the OPerational CRITeria system. Multidimensional item response modelling estimate a bifactor model of psychosis by Mplus, composed of a general factor and five specific sympto…

S126. THE RELATION OF THE PSYCHOSIS CONTINUUM WITH SCHIZOPHRENIA POLYGENIC RISK SCORE AND CANNABIS USE

2020

Abstract Background There has been much debate about whether research into psychosis should be conducted using symptom dimensions as opposed to diagnostic categories. Indeed, dimensions, like categories, may be practical but arbitrary tools for research and clinical practice; hence, they should not be based on psychometric data only. The aim of this study was to externally validate empirically derived symptom dimensions using combined genetic and environmental data. Specifically, we examined the hypothesis that the continuous multivariate distribution of psychosis is a function of cannabis use and genetic liability to schizophrenia, as summarised by polygenic risk score (SZ-PRS). Methods As…

S114. THE EFFICACY OF “URGENT CONSULTATION REQUEST”; PRELIMINARY ANALYSIS OF A REAL-WORLD APP (REMIDCARE) FOR EARLY PSYCHOSIS

2020

Abstract Background Patients are clamming for more personalized and closer clinical attention (Bonet et al. 2018). To this end, we developed RemindCare app. The app conducts daily and weekly assessments and this information is used to prevent relapses, to improve the therapeutic alliance and it is automatically included at the electronic clinical record of the hospital. Moreover, patients can contact clinicians by an “Urgent Consultation Request” (UCR), which is answered by a phone call in a period of 24-48h. This app was introduced in clinical practice in October 2018. Since then, 81 patients met criteria for inclusion and 57/81 (71%) started using the app. The aim of this study is to anal…