Search results for "thoracic"

showing 10 items of 511 documents

Penetrating aortic ulcer post migration of thoracic aortic endoprosthesis: Case report

2021

Introduction Thoracic endovascular aortic repair (TEVAR) is the first treatment option for many thoracic aortic pathologies. Especially after aortic dissections, it is possible to have progression during follow-up with appearance of new lesions on arterial wall. Herein, we report a case of Penetrating Aortic Ulcer (PAU) post release of Thoracic endoprosthesis. Presentation of case A 67-years-old male with hypertension and diabetes mellitus was followed at our hospital after an emergency procedure for Type B aortic dissection (TBAD) complicated by symptomatic large infrarenal AAA and treated with a proximal TEVAR plus chimney for left subclavian artery and PETTICOAT with EVAR for abdominal a…

Post releasemedicine.medical_specialtyTEVARbusiness.industrymedicine.medical_treatmentStentTreatment optionsmedicine.diseaseAortic diseaseProsthesisSettore MED/22 - Chirurgia VascolareSurgeryPenetrating atherosclerotic ulcerPenetrating atherosclerotic ulcermedicine.arteryCase reportcardiovascular systemmedicineThoracic aortaSurgeryArterial wallComplicated aortic B dissectionbusinessMigration endoprosthesis
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Pterostilbene-induced tumor cytotoxicity: a lysosomal membrane permeabilization-dependent mechanism.

2012

The phenolic phytoalexin resveratrol is well known for its health-promoting and anticancer properties. Its potential benefits are, however, limited due to its low bioavailability. Pterostilbene, a natural dimethoxylated analog of resveratrol, presents higher anticancer activity than resveratrol. The mechanisms by which this polyphenol acts against cancer cells are, however, unclear. Here, we show that pterostilbene effectively inhibits cancer cell growth and stimulates apoptosis and autophagosome accumulation in cancer cells of various origins. However, these mechanisms are not determinant in cell demise. Pterostilbene promotes cancer cell death via a mechanism involving lysosomal membrane …

PterostilbeneCancer Treatmentlcsh:MedicineApoptosisResveratrolBiochemistryLung and Intrathoracic Tumorschemistry.chemical_compoundMolecular cell biologyRNA interferenceNeoplasmsPhagosomesStilbenesDrug DiscoveryBreast TumorsBasic Cancer Researchlcsh:ScienceCytotoxicitySkin TumorsApoptotic Signaling CascadeCellular Stress ResponsesMultidisciplinaryMicroscopy ConfocalCell DeathMalignant MelanomaFlow CytometryCellular StructuresSignaling CascadesCell biologyEukaryotic CellsOncologyCaspasesMedicineCellular TypesCell DivisionResearch ArticleSignal TransductionProgrammed cell deathDrugs and DevicesDrug Research and DevelopmentMitosisAntineoplastic AgentsBiologyPermeabilityCell GrowthInhibitory Concentration 50NecrosisComplementary and Alternative MedicineCell Line TumorGastrointestinal TumorsAutophagyHumansHSP70 Heat-Shock ProteinsBiologyCell ProliferationDose-Response Relationship DrugL-Lactate DehydrogenaseCell growthlcsh:RAutophagyProteinsCancers and NeoplasmsRegulatory ProteinschemistrySubcellular OrganellesApoptosisResveratrolCancer celllcsh:QGene expressionLysosomesCytometryPloS one
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New evidence in one-lung ventilation

2017

Mechanical ventilation in thoracic surgery has undergone significant changes in recent years due to the implementation of the protective ventilation. This review will analyze recent ventilatory strategies in one-lung ventilation. A MEDLINE research was performed using Mesh term "One-Lung Ventilation" including randomized clinical trials, metanalysis, reviews and systematic reviews published in the last 6 years. Search was performed on 21st March 2017. A total of 75 articles were initially found. After title and abstract review 14 articles were included. Protective ventilation is not simply synonymous of low tidal volume ventilation, but it also includes routine use of PEEP and alveolar recr…

Pulmonary Atelectasismedicine.medical_specialtySwinemedicine.medical_treatmentMEDLINElaw.inventionHypercapniaPositive-Pressure Respiration03 medical and health sciences0302 clinical medicineMeta-Analysis as TopicRandomized controlled trial030202 anesthesiologylawTidal VolumeAnimalsHumansMedicine030212 general & internal medicineExpirationIntensive care medicineRandomized Controlled Trials as TopicMechanical ventilationbusiness.industryGeneral Medicinerespiratory systemOne lung ventilationOne-Lung Ventilationrespiratory tract diseasesSystematic reviewCardiothoracic surgeryModels AnimalVentilation (architecture)Anesthesia Inhalationbusiness
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Bilateral thoracoscopic thymectomy using a novel positioning system.

2013

Several techniques of bilateral video-assisted thoracoscopic extended thymectomy have been proposed, and each has its own proponents. We summarize our experience in 20 patients who underwent bilateral video-assisted thoracoscopic extended thymectomy, using a new patient positioning that amplifies the thoracoscopic view of the cardiophrenic regions which are often difficult to visualize with standard techniques. In all cases, en-bloc thymectomy with complete dissection of the mediastinal fatty tissue was achieved without sternal retractors or additional incisions.

Pulmonary and Respiratory MedicineAdultMalemedicine.medical_specialtyAdolescentmedicine.medical_treatmentMyasthenia gravis thoracic surgery video-assisted thymectomy thymus glandMyasthenia graviPatient positioningExtended thymectomyThymus GlandPatient PositioningYoung AdultmedicineHumansVideo assistedThoracoscopic thymectomyvideo-assistedbusiness.industryThoracic Surgery Video-AssistedMedicine (all)General MedicineMiddle Agedmedicine.diseaseThymectomythoracic surgeryMyasthenia gravisSurgeryThymectomySettore MED/18 - Chirurgia GeneraleDissectionCardiothoracic surgerySurgeryFemaleCardiology and Cardiovascular MedicinebusinessHumanAsian cardiovascularthoracic annals
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The use of video-assisted thoracic surgery in the management of Pancoast tumours

2010

We describe our experience using video-assisted thoracic surgery (VATS) as an adjunct to the surgical management of Pancoast tumors. Between March 2004 and November 2009, 13 patients with Pancoast tumors were included in this study. Surgery was performed by positioning the patient to allow either an anterior or a posterior thoracotomy. VATS was employed to explore the pleural cavity, to optimize the surgical access and as an assistance during surgical resection. Three patients with pleural carcinosis at thoracoscopy did not undergo further surgery. Seven lobectomies and three wedge resections were performed with an en bloc chest-wall resection and mediastinal lymphadenectomy. The surgical a…

Pulmonary and Respiratory MedicineAdultMalemedicine.medical_specialtyTime FactorsCarcinosismedicine.medical_treatmentBlood Loss SurgicalGeneral thoracic surgerySuperior sulcus tumorsPatient PositioningGeneral thoracic surgery; Lung cancer; Superior sulcus tumorsPancoast tumorPneumonectomymedicineThoracoscopyHumansThoracotomyPneumonectomyAgedmedicine.diagnostic_testbusiness.industryThoracic Surgery Video-AssistedMediastinumPancoast SyndromePleural cavityLength of StayMiddle Agedmedicine.diseaseNeoadjuvant TherapySurgerySettore MED/18 - Chirurgia Generalemedicine.anatomical_structureTreatment OutcomeItalyThoracotomyCardiothoracic surgeryChemotherapy AdjuvantLymph Node ExcisionSurgeryFemaleRadiotherapy AdjuvantRadiologyLung cancerCardiology and Cardiovascular Medicinebusiness
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A comparative analysis of Pancoast tumour resection performed via video-assisted thoracic surgery versus standard open approaches.

2014

OBJECTIVES: The aim of the present paper was to conduct a comparative analysis of outcomes after thoracoscopic resection versus standard thoracotomy approach in the treatment of Pancoast tumours. METHODS: All consecutive patients with Pancoast tumours undergoing surgical treatment from March 2000 to November 2012 were enrolled. Patients were divided into 2 groups according to whether a thoracoscopic or standard thoracotomy approach was adopted. In addition to morbidity and mortality, (i) intensity of pain; (ii) respiratory function focusing on the postoperative value and its variation with respect to the predicted value (Delta); (iii) analgesic consumption at different times during the post…

Pulmonary and Respiratory MedicineAdultMalemedicine.medical_specialtyVital capacityTime Factorsmedicine.medical_treatmentSettore MED/21 - Chirurgia ToracicaKaplan-Meier EstimatePreoperative carePancoast tumour; Superior sulcus tumour; Video-assisted thoracoscopic resection; Surgery; ThoracotomyPancoast tumorRisk FactorsmedicineHumansRespiratory functionNeoplasm InvasivenessThoracotomyLung cancerPneumonectomySurvival rateAgedNeoplasm StagingPain MeasurementRetrospective StudiesAnalgesicsPain Postoperativebusiness.industryThoracic Surgery Video-AssistedSuperior sulcus tumourPancoast SyndromeRecovery of FunctionPleural cavityMiddle Agedmedicine.diseaseSurgerySettore MED/18 - Chirurgia Generalemedicine.anatomical_structureTreatment OutcomeItalyThoracotomyAnesthesiaPancoast tumourVideo-assisted thoracoscopic resectionSurgeryFemaleLung cancerCardiology and Cardiovascular MedicinebusinessInteractive cardiovascular and thoracic surgery
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Symptomatic atherosclerotic occlusive disease of all supra-aortic arch vessels treated with total aortic arch rerouting.

2011

We present an uncommon case of symptomatic atherosclerotic occlusive disease of all supra-aortic arch vessels and its surgical treatment by total aortic arch rerouting after endarteriectomy of all target vessels.

Pulmonary and Respiratory MedicineAortic archmedicine.medical_specialtyAortographymedicine.medical_treatmentAortic DiseasesHemodynamicsAorta ThoracicConstriction PathologicEndarterectomyAortographySeverity of Illness IndexMagnetic resonance angiographyBlood Vessel Prosthesis Implantationmedicine.arteryInternal medicinemedicineThoracic aortaHumansArchEndarterectomyAgedAortamedicine.diagnostic_testbusiness.industryHemodynamicsAtherosclerosisTreatment OutcomeRegional Blood Flowcardiovascular systemCardiologySurgeryFemaleCardiology and Cardiovascular MedicinebusinessTomography X-Ray ComputedMagnetic Resonance AngiographyInteractive cardiovascular and thoracic surgery
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Implantation of Gore-Tex chordae on aortic valve leaflet to treat prolapse using "the chordae technique": surgical aspects and clinical results.

2008

Background Repair of prolapsed aortic valve leaflets has been considered a challenging technique for cardiac surgeons. In this paper we describe our surgical approach, "the chordae technique." It consists of the correction of aortic cusp prolapse by shortening the free margin length and of an adjustment of the leaflets coaptation height by anchoring the prolapsing cusp to the aortic wall at the sinotubular junction level. Methods Between February 2003 and December 2006, 26 patients with one or more prolapsed aortic leaflets underwent surgical repair using the new approach. The mean age of patients was 55 ± 10 years. There were 10 (38.5%) patients with grade II aortic valve regurgitation, 4 …

Pulmonary and Respiratory MedicineAortic valveMalemedicine.medical_specialtyAortic Valve InsufficiencyComorbidityAortic aneurysmPostoperative ComplicationsInternal medicinemedicineHumanscardiovascular diseasesCardiac skeletonPolytetrafluoroethyleneAortic valve regurgitationAgedSurgical repairAortic Valve ProlapseHeart Valve Prosthesis ImplantationAortic Aneurysm Thoracicbusiness.industrySinotubular JunctionSuture TechniquesMiddle Agedmedicine.diseaseCombined Modality TherapySurgerymedicine.anatomical_structureCardiothoracic surgeryAortic ValveHeart Valve ProsthesisCirculatory systemcardiovascular systemCardiologyChordae TendineaeSurgeryFemaleCardiology and Cardiovascular MedicinebusinessEchocardiography TransesophagealFollow-Up StudiesThe Annals of thoracic surgery
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Revaskularisation mit der A. gastroepiploica dextra — Bewertung der Indikation und des perioperativen Risikos

1997

Bei 35 Patienten (mittleres Alter 64,0 Jahre (±10,4 Jahre) wurde bei fehlender oder unbrauchbarer V. saphena magna neben der einoder beidseitigen A. thoracica interna (ITA) die rechte A. gastroepiploica (GEA) zur Revaskularisation der rechten Koronararterie (RCA) verwendet. Ausgeschlossen wurden Patienten mit erheblicher Adipositas (Broca-Index >20%) sowie Patienten mit abdominellen Voroperationen. In einem Fall konnte die GEA wegen Plaquebildung nicht verwendet werden. Bei 23 Patienten wurde die GEA mit dem R. interventricularis posterior (RIVP), bei 11 Patienten mit der RCA vor bzw. in Hohe der Crux anastomosiert.

Pulmonary and Respiratory MedicineGynecologyArterial graftsmedicine.medical_specialtybusiness.industryCardiothoracic surgerymedicineSurgeryCardiology and Cardiovascular MedicinebusinessCardiac surgeryZeitschrift für Herz-, Thorax- und Gefäßchirurgie
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Remodeling der Aorta als rekonstruktive Maßnahme für Aneurysmen der Aorta aszendens

2001

Eine weniger haufig gebrauchte Methode zur operativen Therapie des Aszendens-Aneurysmas ist die plastische Rekonstruktion im Sinne einer Reduktionsplastik mit anschliesender Ummantelung der nativen Aorta. Der Vorteil liegt in der vollstandigen Erhaltung der Endothelzellschicht der Aorta und der Beibehaltung der dynamischen Funktion der Sinus Valsalvae.¶ Von 1987–1998 wurden 20 Patienten mit einem Aneurysma verum nach der o.g. Methode operiert. In 9 Fallen (Gruppe I – mittleres Patientenalter 72 Jahre; Spannweite 64–78 Jahre) beschrankte sich der Eingriff auf die plastische Rekonstruktion der Aorta und konsekutive Ummantelung. Bei 11 Patienten (Gruppe II – mittleres Patientenalter 45 Jahre; …

Pulmonary and Respiratory MedicineGynecologymedicine.medical_specialtyCardiothoracic surgerybusiness.industrymedicineSurgeryCardiology and Cardiovascular MedicinebusinessZeitschrift f�r Herz-, Thorax- und Gef��chirurgie
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