Search results for "treatment."
showing 10 items of 17500 documents
Adjuvant capecitabine in triple negative breast cancer patients with residual disease after neoadjuvant treatment: real-world evidence from CaRe, a m…
2023
BackgroundIn triple negative breast cancer patients treated with neoadjuvant chemotherapy, residual disease at surgery is the most relevant unfavorable prognostic factor. Current guidelines consider the use of adjuvant capecitabine, based on the results of the randomized CREATE-X study, carried out in Asian patients and including a small subset of triple negative tumors. Thus far, evidence on Caucasian patients is limited, and no real-world data are available.MethodsWe carried out a multicenter, observational study, involving 44 oncologic centres. Triple negative breast cancer patients with residual disease, treated with adjuvant capecitabine from January 2017 through June 2021, were recrui…
Transcranial Magnetic Stimulation and Neuroimaging Coregistration
2013
The development of neuroimaging techniques is one of the most impressive advancements in neuroscience. The main reason for the widespread use of these instruments lies in their capacity to provide an accurate description of neural activity during a cognitive process or during rest. This important advancement is related to the possibility to selectively detect changes of neuronal activity in space and time by means of different biological markers. Specifically, functional magnetic resonance imaging (fMRI), positron emission tomography (PET), single-photon emission computed tomography (SPECT), and nearinfrared spectroscopy (NIRS) use metabolic markers of ongoing neuronal activity to provide a…
Electrocatheter-mediated High-voltage Pulsed Radiofrequency of the Dorsal Root Ganglion in the Treatment of Chronic Lumbosacral Neuropathic Pain
2019
Objectives: Despite the interest in scientific community, there is still poor evidence about pulsed radiofrequency (PRF) efficacy in the treatment of neuropathic pain. In order to determine whether high-voltage PRF and epidural adhesiolysis (PRF-EA) showed better results than epidural adhesiolysis alone (EA), a randomized, double-blind, comparative-effectiveness study was conducted in patients with chronic lumbosacral radiating pain and neuropathic features. Materials and Methods: A total of 41 patients were randomly allocated to 2 groups. Twenty-one patients were randomized to receive 2 cycles of 240 seconds high-voltage PRF followed by the injection of local anesthetics, hyaluronidase, an…
Niewydolność serca - problem medyczny, ekonomiczny i społeczny
2019
Pierwsze wzmianki o chorobie, którą dzisiaj określamy jako niewydolność serca, pochodzą z czasów antycznych. Epidemiologia objawowej niewydolności serca jest dobrze poznana, szczególnie w Europie. Na naszym kontynencie niewydolność serca występuje u około 2% dorosłej populacji. W artykule przedstawiono: defnicję, epidemiologię i rokowanie chorych z niewydolnością serca. Opracowanie charakteryzuje aktualne metody farmakoterapii i leczenia interwencyjnego. Ważnym elementem postępowania u chorych z niewydolnością serca jest rehabilitacja medyczna i przestrzeganie zasad proflaktyki chorób sercowo-naczyniowych zalecanych przez Europejskie Towarzystwo Kardiologiczne. Artykuł porusza również temat…
Person reference as a device for constructing experiences as typical in group therapy.
2008
Sharing one's experiences is a crucial activity in group therapies. In such therapies, groups can be either constituted around one problem or goal common to all the clients, or the group can work as a place in which clients can learn from one another and share experiences whether their individual problems are similar or not. Almost all (psycho) therapy types have a group application, and groups are assumed to be rather efficient in psychological progressing (see, e.g. Corey, 1986; Wootton, 1977). In this article I will concentrate on one type of group therapy, namely the Minnesota model group therapy for addicts, and examine how the clients share experiences and, especially, how they constr…
Modelling the Electromechanical Impedance Method for the Prediction of the Biomechanical Behavior of Dental Implant Stability
2015
Abstract We propose the electromechanical impedance (EMI) technique to assess the stability of dental implants. The technique consists of bonding a piezoelectric transducer to the element to be monitored. Conventionally, electromechanical admittance is used to diagnose structural damage. In this study, we created a 3D finite element model to mimic a transducer bonded to the abutment of a dental implant placed in a host bone site. We simulated the healing after surgery by changing the Young's modulus of the bone-implant interface. The results show that as the Young's modulus of the interface increases, the electromechanical characteristic of the transducer changes.
Brain Modulation by Electric Currents in Fibromyalgia: A Structured Review on Non-invasive Approach With Transcranial Electrical Stimulation
2018
Fibromyalgia syndrome (FMS) is a complex disorder where widespread musculoskeletal pain is associated with many heterogenous symptoms ranging from affective disturbances to cognitive dysfunction and central fatigue. FMS is currently underdiagnosed and often very poorly responsive to pharmacological treatment. Pathophysiology of the disease remains still obscure even if in the last years fine structural and functional cerebral abnormalities have been identified, principally by neurophysiological and imaging studies delineating disfunctions in pain perception, processing and control systems. On such basis, recently, neurostimulation of brain areas involved in mechanism of pain processing and …
Rhabdomyosarcoma of the head and neck in pediatric patients: a systematic review.
2022
Rhabdomyosarcoma (RMS) is a soft tissue malignant tumor of mesenchymal cell origin, which usually shows variable differentiation of muscle cells. It is the most common solid sarcoma in children. The most usual site of occurrence are the head and neck regions. RMS presents a variety of histologic features, and so differential diagnosis with other small round cell tumors is needed. Hence, it has been very useful to the field to undertake additional immunohistochemical studies to determine the diagnosis and, on occasions, to assign subtype tumors. A systematic review of three databases (Medline, Biological Science Collection and Health & Medical Collection) was carried out with the purpose of …
Betatrophin Levels Are Related to the Early Histological Findings in Nonalcoholic Fatty Liver Disease
2021
Betatrophin, a liver hormone, regulates glucose and lipid metabolism. We investigated the betatrophin levels in nonalcoholic fatty liver disease (NAFLD) and searched for any relationship with histological severity and metabolic parameters. Fifty males with NAFLD [Nonalcoholic Steatohepatitis (NASH) (n = 32)
A four-session acceptance and commitment therapy based intervention for depressive symptoms delivered by masters degree level psychology students: a …
2013
Background:Depressive symptoms are one of the main reasons for seeking psychological help. Shorter interventions using briefly trained therapists could offer a solution to the ever-rising need for early and easily applicable psychological treatments.Aims:The current study examines the effectiveness of a four-session Acceptance and Commitment Therapy (ACT) based treatment for self-reported depressive symptoms administered by Masters level psychology students.Method:This paper reports the effectiveness of a brief intervention compared to a waiting list control (WLC) group. Participants were randomized into two groups: ACT (n= 28) and waiting list (n= 29). Long-term effects were examined using…