Search results for "α-aminonitriles"

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Simple two-step synthesis of 2,4-disubstituted pyrroles and 3,5-disubstituted pyrrole-2-carbonitriles from enones

2014

The cyclocondensation of enones with aminoacetonitrile furnishes 3,4-dihydro-2H-pyrrole-2-carbonitriles which can be readily converted to 2,4-disubstituted pyrroles by microwave-induced dehydrocyanation. Alternatively, oxidation of the intermediates produces 3,5-disubstituted pyrrole-2-carbonitriles.

heterocyclescyclizationOrganic ChemistryTwo stepα-aminonitrilesCombinatorial chemistryFull Research Papermicrowave-assisted synthesislcsh:QD241-441Chemistrychemistry.chemical_compoundchemistrylcsh:Organic chemistrySimple (abstract algebra)pyrrolesAminoacetonitrilelcsh:Qlcsh:SciencePyrroleBeilstein Journal of Organic Chemistry

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