0000000000001783

AUTHOR

David Esteve-bruna

showing 3 related works from this author

Prefoldins contribute to maintaining the levels of the spliceosome LSM2–8 complex through Hsp90 in Arabidopsis

2020

14 p.-7 fig.-2 tab.

0106 biological sciencesSpliceosomeAcademicSubjects/SCI00010RNA SplicingMutantArabidopsis01 natural sciencesChaperonin//purl.org/becyt/ford/1 [https]03 medical and health sciencesGene Expression Regulation PlantArabidopsisRNA and RNA-protein complexesGeneticsHSP90 Heat-Shock Proteins//purl.org/becyt/ford/1.6 [https]030304 developmental biologyprefoldins0303 health sciencesbiologyArabidopsis ProteinsRNA-Binding Proteinsbiology.organism_classificationHsp903. Good healthCell biologyProteostasisMultiprotein ComplexesMutationRNA splicingSpliceosomesbiology.proteinLSM2-8 complexspliceosomeSmall nuclear RNAMolecular ChaperonesProtein Binding010606 plant biology & botany
researchProduct

A genetic approach reveals different modes of action of prefoldins

2021

17 p.-7 fig.

Regular IssueAcademicSubjects/SCI01280PhysiologyProtein subunitMutantArabidopsisPlant ScienceChaperonin03 medical and health sciences0302 clinical medicineArabidopsisGeneticsBIOQUIMICA Y BIOLOGIA MOLECULARArabidopsis thalianaTranscription factorActinResearch Articles030304 developmental biology0303 health sciencesAcademicSubjects/SCI01270biologyErrataArabidopsis ProteinsAcademicSubjects/SCI02288AcademicSubjects/SCI02287AcademicSubjects/SCI02286Genes Development and EvolutionPrefoldin complexbiology.organism_classificationCell biologyGENETICA030217 neurology & neurosurgeryMolecular ChaperonesTranscription Factors
researchProduct

A genetic approach to dissect the role of prefoldins in Arabidopsis

2021

SummaryThe prefoldin complex (PFDc) was identified in humans as co-chaperone of the cytosolic chaperonin TRiC/CCT. It is conserved in eukaryotes and is composed of subunits PFD1 to 6. PFDc-TRiC/CCT operates folding actin and tubulins. In addition to this function, PFDs participate in a wide range of cellular processes, both in the cytoplasm and in the nucleus, and their malfunction cause developmental alterations and disease in animals, and altered growth and environmental responses in yeast and plants. Genetic analyses in yeast indicate that not all functions performed by PFDs require the participation of the canonical complex. The lack of systematic genetic analyses in higher eukaryotes m…

CytoplasmProtein subunitArabidopsisMutantBiologyPrefoldin complexbiology.organism_classificationTranscription factorActinFunction (biology)Cell biology
researchProduct