0000000000002940
AUTHOR
M. Teresa Lo Giudice
119Sn mössbauer, IR, 1H NMR spectroscopic and thermal decomposition studies on organotin(IV) adducts with glycylglycine
Abstract The complexes R2SnCl2·(H2glygly), (H2glygly = glycylglycine) (R = Me, Bun, Octn, Ph) and RSnCl3·(H2glygly)
Interactions of organotins with biological systems
The bonding and structure in the environments of tin atoms in organotin-biological molecules has been investigated by 119Sn Mossbauer spectroscopy, mainly through the rationalization of the nuclear quadrupole splitting parameter by pointcharge model approaches. Organotin moieties R2SnIV and R3SnIV (R = Me, nBu, Ph) generally assume trigonal-bipyramidal type configurations in membranes of human erythrocytes, when incubated with whole erythrocytes and erythrocyte ghosts at the level of micromolar (μmol dm−3) organotin per mg of membrane protein. Corresponding structures are assumed by Me2SnIV and Me3SnIV in the cytoplasm. Ethanolic Me2SnCl2 yielded distorted trans-octahedral species when reac…