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AUTHOR

Daniela Callari

showing 3 related works from this author

Bovine seminal ribonuclease is cytotoxic for both malignant and normal telomerase-positive cells

2005

Bovine seminal-ribonuclease (BS-RNase) is a member of the 'ribonucleases with special biological actions' family since it possesses specific anti-tumour, anti-spermatogenic and embryotoxic activities and exerts an immunosuppressive effect on T lymphocytes. In previous studies it was demonstrated that BS-RNase induced apoptosis in proliferating, malignant and normal cells and that telomerase activity loss also caused apoptotic death in neoplastic cells. Since an obvious relationship between cell proliferation and telomerase activity exists, the aim of this work was to study if the pro-apoptotic cytotoxic action exerted by BS-RNase on proliferating malignant cells (HT29) and proliferating nor…

Cancer ResearchTelomeraseTime FactorsT-LymphocytesCellular differentiationCytotoxicityBlotting WesternDown-RegulationTetrazolium SaltsAntineoplastic AgentsApoptosisEnzyme-Linked Immunosorbent AssayBiologyHT29 CellsCell Line TumorEndoribonucleasesAnimalsHumansCytotoxic T cellTelomerase reverse transcriptaseLymphocytesRNA MessengerTelomeraseBovine seminal-ribonuclease; Cytotoxicity; HTR; Nucleolar localization; TelomeraseCell ProliferationReverse Transcriptase Polymerase Chain ReactionCell growthCell DifferentiationCell cycleNucleolar localizationMolecular biologyThiazolesBovine seminal-ribonucleaseMicroscopy FluorescenceOncologyCell cultureLeukocytes MononuclearMicroscopy Electron ScanningRNACattleHTRCell NucleolusImmunosuppressive Agents
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Feasibility in routine clinical setting of combined resting-state fMRI and DTI-tractography for surgical planning of brain tumors

2020

Purpose Methods and materials Results Conclusion Personal information and conflict of interest References

fMRI DTI-tractography Brain Neuroimaging resting-state fMRINeuroradiology brainRetrospectivePerformed at one institutionDiagnostic or prognostic studyMRDiagnostic procedureTechnical aspectsMRIMR-Diffusion/PerfusionMR-Functional imagingCancer
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Beta-2-glycoprotein I is growth regulated and plays a role as survival factor for hepatocytes

2004

Beta-2-glycoprotein I (beta(2)GPI) is mainly produced by the liver and is found in plasma partially associated to lipoproteins. Although various properties have been attributed to this protein, its physiological role remains still unclear. We investigated its expression in cultured liver cells and in regenerating liver. Expression studies in HepG2 cells demonstrate that beta(2)GPI mRNA is regulated in a cell cycle-dependent manner, with very low expression in low cycling conditions and increasing levels in proliferating cells. p21 WAF-dependent growth arrest, induced by butyrate treatment, down-regulate beta(2)GPI mRNA levels. Immunolocalization in normal rat liver shows a non-homogeneous p…

medicine.medical_specialtyRegenerating liverSurvivalCell SurvivalCell cycle expressionCellCell Culture TechniquesButyrateBiologyBiochemistrychemistry.chemical_compoundAlbuminsInternal medicineGene expressionmedicineAnimalsHumansBeta 2-Glycoprotein IRats WistarGlycoproteinsAlbuminSodium butyrateCell BiologyLiver RegenerationRatsBeta-2-glycoprotein ICell biologyButyratesEndocrinologymedicine.anatomical_structureGene Expression RegulationLiverchemistrybeta 2-Glycoprotein IHepatocytesApolipoprotein HHepatic stellate cellGDF15The International Journal of Biochemistry & Cell Biology
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