0000000000005117
AUTHOR
Andrés López-roldán
Bibliometric analysis of the scientific production of literature on peri-implant diseases in the Web of Science.
Background The exponential increase in implant placement worldwide and the high prevalence of its associated pathologies have prompted an increasing contribution by the scientific community to the number of publications related to peri-implant pathologies. Purpose The objective of this work is to carry out a bibliometric analysis of scientific production on peri-implant diseases. Materials and methods The search strategy included titles, keywords, and abstracts based on the term peri-implantitis and all the possible combinations existing in Science Citation Index Expanded (SCIE) of the main collection of Web of Science. Two limits were established: the document typology was limited to Artic…
Performance of the dentogingival junction with mta and biodentine on the treatment of invasive cervical resorptions. A literature review and case report
Invasive cervical resorption (ICR) is an uncommon phenomenon (0.1%), however, it represents a challenge to the structural and functional integrity of the dentogingival junction, as well as a risk for the survival of the affected tooth. They are characterized by their location and invasive character, being able to appear in any tooth of the permanent dentition. It shows up after the damage to the cervical insertion apparatus, leaving the pulp without participation in the origin of the lesion. They may appear just below the junctional epithelium or at a more apical level. The MTA® (Dentsply, Tulsa dental, Tulsa OK) and the Biodentine® (Septodent, Saint Maur of Fossés, France) are two biomater…
MicroRNAs and periodontal disease: a qualitative systematic review of human studies.
Purpose MicroRNAs (miRNAs) are epigenetic post-transcriptional regulators that modulate gene expression and have been identified as biomarkers for several diseases, including cancer. This study aimed to systematically review the relationship between miRNAs and periodontal disease in humans, and to evaluate the potential of miRNAs as diagnostic and prognostic biomarkers of disease. Methods The review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines (reference number CRD42020180683). The MEDLINE, Scopus, Cochrane Library, Embase, Web of Science, and SciELO databases were searched for clinical studies conducted in humans investigating pe…
A controlled clinical study of periodontal health in anticoagulated patients : assessment of bleeding on probing
Background According to the Spanish Society of Cardiology, 700,000 patients receive oral anticoagulants, and in these cases bleeding on probing (BOP) could be altered. However, no studies have analyzed the periodontal status of these patients and the effects anticoagulants may have upon BOP. A study was made of the possible relationship between plaque index, probing depth, INR (International Normalized Ratio) and acenocoumarol dose versus the clinical signs of BOP in a sample of anticoagulated patients. Likewise, an analysis was made of oral hygiene habits and attitude towards bleeding in these patients. Material and Methods A controlled observational clinical study was made in La Ribera Ho…
Effects of photodynamic therapy in periodontal treatment: A randomized, controlled clinical trial
Aim To evaluate the effects of photodynamic therapy (PDT) in the nonsurgical treatment of chronic periodontitis. Materials and methods A randomized, single-blind, controlled, parallel-group clinical trial was performed. Sixty patients were enrolled: 20 healthy controls and 40 patients with periodontitis. The 40 patients were randomized for scaling and root planing (SRP) or SRP+PDT. Periodontal (plaque index, probing depth, clinical recession, clinical attachment level, bleeding on probing, and gingival crevicular fluid volume, corresponding to 381 vs 428 critical sites), microbiological (Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia, Treponema dentico…
Comparison of the clinical effects of white brand toothbrushes versus Vitis Suave®
Background: There has been an increase in the use of white label manual toothbrushes and a greater increase in inquiries for discomfort of the gingiva and mucosa. Material and Methods: A randomized, double-blind, cross-over clinical trial was made of four white brand toothbrushes versus a control brush (Vitis Suave®), with the recording of plaque index, bleeding upon probing, and gingival abrasions following utilization of the different brushes. Results: All the brushes except Deliplus® were equally effective in terms of plaque removal ( p <0.05). Vitis Suave® and Veckia® were the brushes associated to the greatest increase in minor abrasions ( p <0.01), while Veckia®, Carrefour® and Deluxe…
Epigenetics and periodontics : a systematic review
Background Despite decades of research, our knowledge of several important aspects of periodontal pathogenesis remains incomplete. Epigenetics allows to perform dynamic analysis of different variations in gene expression, providing this great advantage to the static measurement provided by genetic markers. The aim of this systematic review is to analyze the possible relationships between different epigenetic mechanisms and periodontal diseases, and to assess their potential use as biomarkers of periodontitis. Material and Methods A systematic search was conducted in six databases using MeSH and non-MeSH terms. The review fulfilled PRISMA criteria (Preferred Reporting Items for Systematic re…
miR-1226 detection in GCF as potential biomarker of chronic periodontitis: a pilot study
Background The study and identification of new biomarkers for periodontal disease, such as microRNAs (miRNAs), may give us more information about the location and severity of the disease and will serve as a basis for treatment planning and disease-monitoring. miRNAs are a group of small RNAs which are involved in gene regulation by binding to their messenger RNA target (mRNA). In this pilot study, the procedure for purifying miRNAs from gingival crevicular fluid (GCF) was, for the first time, described. In addition, the concentration of miRNAs in GCF was analyzed and compared between patients with moderate or severe chronic periodontitis (CP) and healthy controls. Material and Methods GCF s…