0000000000006653

AUTHOR

Qiang Zhao

0000-0001-8334-2580

The protease complex consisting of dipeptidyl peptidase IV and seprase plays a role in the migration and invasion of human endothelial cells in collagenous matrices

Abstract Dipeptidyl peptidase IV (DPP4/CD26) and seprase/fibroblast activation protein α are homologous type II transmembrane, homodimeric glycoproteins that exhibit unique prolyl peptidase activities. Human DPP4 is ubiquitously expressed in epithelial and endothelial cells and serves multiple functions in cleaving the penultimate positioned prolyl bonds at the NH2 terminus of a variety of physiologically important peptides in the circulation. Recent studies showed a linkage between DPP4 and down-regulation of certain chemokines and mitogenic growth factors, and degradation of denatured collagens (gelatin), suggesting a role of DPP4 in the cell invasive phenotype. Here, we found the existen…

research product

Measurement of Λ baryon polarization in e+e−→ΛΛ¯ at s=3.773  GeV

research product

Study ofe+e−→ωχcJat Center of Mass Energies from 4.21 to 4.42 GeV

Based on data samples collected with the BESIII detector at the BEPCII collider at nine center of mass energies from 4.21 to 4.42 GeV, we search for the production of e(+)e(-) -> omega chi(cJ) (J = 0, 1, 2). The process e(+)e(-) -> omega chi(c0) is observed for the first time, and the Born cross sections at root s = 4.23 and 4.26 GeV are measured to be (55.4 +/- 6.0 +/- 5.9) and (23.7 +/- 5.3 +/- 3.5) pb, respectively, where the first uncertainties are statistical and the second are systematic. The omega chi(c0) signals at the other seven energies and the e(+)e(-) -> omega chi(c1) and omega chi(c2) signals are not significant, and the upper limits on the cross sections are determined. By ex…

research product

Precision measurement of the D*(0) decay branching fractions

WOS: 000349437800001

research product

Search forηandη′invisible decays inJ/ψ→ϕηandϕη′

Using a sample of (225.3 +/- 2.8) x 10(6) J/psi decays collected with the BESIII detector at BEPCII, searches for invisible decays of eta and eta ' in J/psi -> phi eta and phi eta ' are performed. Decays of phi -> K+K- are used to tag the eta and eta ' decays. No signals above background are found for the invisible decays, and upper limits at the 90% confidence level are determined to be 2.6 x 10(-4) for the ratio B(eta -> invisible)/B(eta ->gamma gamma) and 2.4 x 10(-2) for B(eta '-> invisible)/B(eta '->gamma gamma). These limits may be used to constrain light dark matter particles or spin-1 U bosons. DOI: 10.1103/PhysRevD.87.012009

research product

Observation of theψ(1 D23)State ine+e−→π+π−γχc1at BESIII

research product

Measurement of the e+e−→π+π−J/ψ cross section in the vicinity of 3.872 GeV

research product

Measurement of ψ(3686)→ΛΛ¯η and ψ(3686)→ΛΛ¯π0 decays

research product

Measurements of baryon pair decays of chi(cJ) mesons

Using 106 $\times 10^{6}$ $\psi^{\prime}$ decays collected with the BESIII detector at the BEPCII, three decays of $\chi_{cJ}$ ($J=0,1,2$) with baryon pairs ($\llb$, $\ssb$, $\SSB$) in the final state have been studied. The branching fractions are measured to be $\cal{B}$$(\chi_{c0,1,2}\rightarrow\Lambda\bar\Lambda) =(33.3 \pm 2.0 \pm 2.6)\times 10^{-5}$, $(12.2 \pm 1.1 \pm 1.1)\times 10^{-5}$, $(20.8 \pm 1.6 \pm 2.3)\times 10^{-5}$; $\cal{B}$$(\chi_{c0,1,2}\rightarrow\Sigma^{0}\bar\Sigma^{0})$ = $(47.8 \pm 3.4 \pm 3.9)\times 10^{-5}$, $(3.8 \pm 1.0 \pm 0.5)\times 10^{-5}$, $(4.0 \pm 1.1 \pm 0.5) \times 10^{-5}$; and $\cal{B}$$(\chi_{c0,1,2}\rightarrow\Sigma^{+}\bar\Sigma^{-})$ = $(45.4 \pm…

research product

Search for hyperon ΔS=ΔQ violating decay Ξ0→Σ−e+νe

research product

Evidence forηc(2S)inψ(3686)→γKS0K±π∓π+π−

We search for the M1 radiative transition psi(3686) -> gamma eta(c)(2S) by reconstructing the exclusive eta(c)(2S) -> (KSK +/-)-K-0 pi(-/+)pi(+)pi(-) decay using 1.06 X 10(8) psi(3686) events collected with the BESIII detector. The signal is observed with a statistical significance of greater than 4 standard deviations. The measured mass of the eta(c)(2S) is 3646.9 +/- 1.6(stat) +/- 3.6(syst) MeV/c(2), and the width is 9.9 +/- 4.8(stat) +/- 2.9(syst) MeV/c(2). The product branching fraction is measured to be B(psi(3686) -> gamma eta(c)(2S)) X B(eta(c)(2S) -> gamma(KSK +/-)-K-0 pi(-/+)pi(+)pi(-) = (7.03 +/- 2.10(stat) +/- 0.70(syst)) X 10(-6). This measurement complements a previous BESIII m…

research product

p–n Metallophosphor based on cationic iridium(iii) complex for solid-state light-emitting electrochemical cells

An ionic transition-metal complex for improved charge transporting properties was designed, containing both n-type dimesitylboryl (BMes2) and p-type carbazole groups. The complex, [Ir(Bpq)2(CzbpyCz)]PF6 (1) (Bpq = 2-[4-(dimesitylboryl)phenyl] quinoline, CzbpyCz = 5,5′-bis(9-hexyl-9H-carbazol-3-yl)-2,2′-bipyridine) and its equivalent in which the BMes2 groups were substituted with carbazole moieties were evaluated on the photoluminescence and excited state properties in detail. According to the photophysical and electrochemical properties, we concluded that the BMes2 groups can increase the conjugation length of the cyclometalated C^N ligands and greatly enhance the phosphorescence efficienc…

research product

Σ+ and Σ¯− Polarization in the J/ψ and ψ(3686) Decays

From 1310.6 x 10(6) J/psi and 448.1 x 10(6) psi (3686) events collected with the BESIII experiment, we report the first observation of Sigma(+) and (Sigma) over bar (-) spin polarization in e(+)e(- ...

research product

Partial wave analysis ofJ/ψ→γηη

Based on a sample of 2.25 x 10(8) J/psi events collected with the BESIII detector at BEPCII, a full partial wave analysis on J/psi -> gamma eta eta was performed using the relativistic covariant tensor amplitude method. The results show that the dominant 0(++) and 2(++) components are from the f(0)(1710), f(0)(2100), f(0)(1500), f(2)'(1525), f(2)(1810) and f(2)(2340). The resonance parameters and branching fractions are also presented.

research product

Experimental study ofψ′decays toK+K−π0andK+K−η

Using (106 +/- 4) x 10(6) psi ' events accumulated with the BESIII detector at the BEPCII e(+)e(-) collider, we present measurements of the branching fractions for psi' decays to K+K- pi(0) and K+K- eta. In these final states, the decay psi' -> K-2(*) (1430)(+) K- + 10(-5), is observed for the first time, and its branching fraction is measured to be (7.12 +/- 0: 62(stat)(-0.61)(+1.13) (syst)) x 10(-5), which indicates a violation of the helicity selection rule in psi' decays. The branching fractions of psi' -> K* (892)(+) K- + c.c., phi eta, and phi pi(0) are also measured. The measurements are used to test the QCD predictions on charmonium decays.

research product

Observation of the doubly radiative decay η′→γγπ0

Based on a sample of 1.31 billion J/psi events collected with the BESIII detector, we report the study of the doubly radiative decay eta' -> gamma gamma pi(0) for the first time, where the eta' meson is produced via the J/psi -> gamma eta' decay. The branching fraction of eta' -> gamma gamma pi(0) inclusive decay is measured to be B(eta' -> gamma gamma pi(0))(Incl) = (3.20 +/- 0.07(stat) +/- 0.23(sys)) x 10(-3), while the branching fractions of the dominant process eta' -> gamma omega and the non-resonant component are determined to be B(eta' -> gamma omega) x B(omega -> gamma pi(0)) = (23.7 +/- 1.4(stat) +/- 1.8(sys)) x 10(-4) and B(eta' -> gamma gamma pi(0))(NR) = (6.16 +/- 0.64(stat) +/-…

research product

Amplitude analysis and branching fraction measurement of Ds+→K−K+π+π0

We report an amplitude analysis and branching fraction measurement of Ds+→K+K−π+ decay using a data sample of 3.19 fb−1 recorded with BESIII detector at a center-of-mass energy of 4.178 GeV. We perform a model-independent partial wave analysis in the low K+K− mass region to determine the K+K− S-wave line shape, followed by an amplitude analysis of our very pure high-statistics sample. With the detection efficiency based on the amplitude analysis results, the absolute branching fraction is measured to be B(Ds+→K+K−π+)=(5.47±0.08stat±0.13sys)%.

research product

Precise Measurement of the e+e−→π+π−J/ψ Cross Section at Center-of-Mass Energies from 3.77 to 4.60 GeV

The cross section for the process e(+)e(-)-> pi(+) pi(-) J/psi is measured precisely at center-of-mass energies from 3.77 to 4.60 GeV using 9 fb(-1) of data collected with the BESIII detector operating at the BEPCII storage ring. Two resonant structures are observed in a fit to the cross section. The first resonance has a mass of (222.0 +/- 3.1 +/- 1.4) MeV/ c(2) and a width of (44.1 +/- 4.3 +/- 2.0)MeV, while the second one has a mass of (4320.0 +/- 10.4 +/- 7.0)MeV/c(2) and a width of (101.4(- 19.7)(+25.3) +/- 10.2) MeV, where the first errors are statistical and second ones are systematic. The first resonance agrees with the Y(4260) resonance reported by previous experiments. The precisi…

research product

Search for the rare decaysJ/ψ→Ds−ρ+andJ/ψ→D¯0K¯*0

A search for the rare decays of J/psi -> D-S(-) rho(+) + c.c. and J/psi -> D-S(-)rho(+) + c.c.) <(D)over bar(0)<(K)over bar*(0) + c.c.) < 2.5 x 10(-6) at the 90% confidence level.

research product

Observation ofη′→ωe+e−

Based on a sample of eta' mesons produced in the radiative decay J/psi -> gamma eta' in 1.31 x 10(9) J/psi events collected with the BESIII detector, the decay eta' -> omega e(+)e(-) is observed for the first time, with a statistical significance of 8 sigma. The branching fraction is measured to be B(eta' -> omega e(+)e(-)) = (1.97 +/- 0.34(stat) +/- 0.17(syst)) x 10(-4), which is in agreement with theoretical predictions. The branching fraction of eta' -> omega gamma is also measured to be (2.55 +/- 0.03(stat) +/- 0.16(syst)) x 10(-2), which is the most precise measurement to date, and the relative branching fraction B(eta' -> omega e(+)e(-))/B(eta' -> omega gamma) is determined to be (7.7…

research product

Observation of ${{e^+e^- \rightarrow D_s^+} \overline{ D}^{\bf (*)0} {K^-}}$ and study of the P -wave ${{D_s}}$ mesons

Studies of $e^+e^- \to D_s^+ \overline{D}{}^{(*)0}K^-$ and the $P$-wave charmed-strange mesons are performed based on an $e^+e^-$ collision data sample corresponding to an integrated luminosity of 567 pb$^{-1}$ collected with the BESIII detector at $\sqrt{s}= 4.600$ GeV. The processes of $e^+e^-\to D_s^+ \overline{D}{*}^{0} K^-$ and $D_s^+ \overline{D}{}^{0} K^-$ are observed for the first time and are found to be dominated by the modes $D_s^+ D_{s1}(2536)^-$ and $D_s^+ D^*_{s2}(2573)^-$, respectively. The Born cross sections are measured to be $\sigma^{B}(e^+e^-\to D_s^+ \overline{D}{*}^{0} K^-) = (10.1\pm2.3\pm0.8) pb$ and $\sigma^{B}(e^+e^-\to D_s^+ \overline{D}{}^{0} K^-) = (19.4\pm2.3\…

research product

Activation of EDTA-resistant Gelatinases in Malignant Human Tumors

Abstract Among the many proteases associated with human cancer, seprase or fibroblast activation protein α, a type II transmembrane glycoprotein, has two types of EDTA-resistant protease activities: dipeptidyl peptidase and a 170-kDa gelatinase activity. To test if activation of gelatinases associated with seprase could be involved in malignant tumors, we used a mammalian expression system to generate a soluble recombinant seprase (r-seprase). In the presence of putative EDTA-sensitive activators, r-seprase was converted into 70- to 50-kDa shortened forms of seprase (s-seprase), which exhibited a 7-fold increase in gelatinase activity, whereas levels of dipeptidyl peptidase activity remaine…

research product

Measurements of absolute branching fractions forΛc+→Ξ0K+and Ξ(1530)0K+

Abstract We report the first measurements of absolute branching fractions for the W -exchange-only processes Λ c + → Ξ 0 K + and Λ c + → Ξ ( 1530 ) 0 K + with the double-tag technique, by analyzing an e + e − collision data sample, that corresponds to an integrated luminosity of 567 pb −1 collected at a center-of-mass energy of 4.6 GeV by the BESIII detector. The branching fractions are measured to be B ( Λ c + → Ξ 0 K + ) = ( 5.90 ± 0.86 ± 0.39 ) × 10 − 3 and B ( Λ c + → Ξ ( 1530 ) 0 K + ) = ( 5.02 ± 0.99 ± 0.31 ) × 10 − 3 , where the first uncertainties are statistical and the second systematic. Our results are more precise than the previous relative measurements.

research product

Measurement of thee+e−→ηJ/ψcross section and search fore+e−→π0J/ψat center-of-mass energies between 3.810 and 4.600 GeV

Using data samples collected with the BESIII detector operating at the BEPCII collider at 17 center-of-mass energies from 3.810 to 4.600 GeV, we perform a study of e(+)e(-) -> eta J/psi and pi(0)J/psi The Born cross sections of these two processes are measured at each center-of-mass energy. The measured energy-dependent Born cross section for e(+)e(-) -> eta J/psi shows an enhancement around 4.2 GeV. The measurement is compatible with an earlier measurement by Belle.

research product

Observation of a Charged Charmoniumlike Structure ine+e−→(D*D¯*)±π∓ats=4.26  GeV

We study the process e(+)e(-) -> (D* (D) over bar*)(+/-)pi(-/+) at a center-of-mass energy of 4.26 GeV using a 827 pb(-1) data sample obtained with the BESIII detector at the Beijing Electron Positron Collider. Based on a partial reconstruction technique, the Born cross section is measured to be (137 +/- 9 +/- 15) pb. We observe a structure near the (D* (D) over bar*)(+/-) threshold in the pi(-/+) recoil mass spectrum, which we denote as the Z(c)(+/-) (4025). The measured mass and width of the structure are (4026.3 +/- 2.6 +/- 3.7) MeV/c(2) and (24.8 +/- 5.6 +/- 7.7) MeV, respectively. Its production ratio sigma(e(+)e(-) -> Z(c)(+/-)(4025)pi(-/+)-> (D* (D) over bar*)(+/-)pi(-/+)/sigma(e(+)e…

research product

Precise Measurement of the e+e− → π+π−J/ψ Cross Section at Center-of-Mass Energies from 3.77 to 4.60 GeV

The cross section for the process e(+)e(-)-> pi(+) pi(-) J/psi is measured precisely at center-of-mass energies from 3.77 to 4.60 GeV using 9 fb(-1) of data collected with the BESIII detector operating at the BEPCII storage ring. Two resonant structures are observed in a fit to the cross section. The first resonance has a mass of (222.0 +/- 3.1 +/- 1.4) MeV/ c(2) and a width of (44.1 +/- 4.3 +/- 2.0)MeV, while the second one has a mass of (4320.0 +/- 10.4 +/- 7.0)MeV/c(2) and a width of (101.4(- 19.7)(+25.3) +/- 10.2) MeV, where the first errors are statistical and second ones are systematic. The first resonance agrees with the Y(4260) resonance reported by previous experiments. The precisi…

research product

Search for baryon- and lepton-number violating decays D0→p¯e+ and D0→pe−

research product

Precision measurements of branching fractions forψ′→π0J/ψandηJ/ψ

We present a precision study of the psi' -> pi(0)J/Psi and eta J/Psi decay modes. The measurements are obtained using 106 x 10(6) psi' events accumulated with the BESIII detector at the BEPCII e(+)e(-) collider operating at a center-of-mass energy corresponding to the psi' mass. We obtain B(psi' -> pi(0)J/Psi) = (1.26 +/- 0.02(stat) +/- 0.03(syst)) x 10(-3) and B(psi' -> eta J/Psi) = (33.75 +/- 0.17(stat) +/- 0.86(syst)) x 10(-3). The branching fraction ratio R = B(psi'->pi(0)J/psi)/B(psi'->eta J/psi) is determined to be (3.74 +/- 0.06(stat) +/- 0.04(syst)) x 10(-2). The precision of these measurements of B(Psi' -> pi(0)J/Psi) and R represent a significant improvement over previously publis…

research product

Anomaly Detection and Classification of Household Electricity Data : A Time Window and Multilayer Hierarchical Network Approach

With the increasing popularity of the smart grid, huge volumes of data are gathered from numerous sensors. How to classify, store, and analyze massive datasets to facilitate the development of the smart grid has recently attracted much attention. In particular, with the popularity of household smart meters and electricity monitoring sensors, a large amount of data can be obtained to analyze household electricity usage so as to better diagnose the leakage and theft behaviors, identify man-made tampering and data fraud, and detect powerline loss. In this paper, the time window method is first proposed to obtain the features and potential periodicity of household electricity data. Combining th…

research product