0000000000006728

AUTHOR

M. Danova

showing 4 related works from this author

Dose-dense chemotherapy and the onset of anemia: New insights

2007

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5-Fluorouracil plus interferon α-2a compared to 5-fluorouracil alone in the treatment of advanced colon carcinoma: A multicentric randomized study

1998

Biochemical modulation is one of the most interesting fields in cancer chemotherapy. Interferon-alpha (IFNalpha) is a cytokine that is able to influence the pharmacodynamics of 5-fluorouracil (5FU) through a number of mechanisms. With the aim of confirming some data emerging from the literature, we initiated a multicentric randomized study comparing the combination of 5FU and IFNalpha-2a with 5FU alone in the treatment of advanced or metastatic colon cancer. A group of 205 colon cancer patients (104 in the 5FU arm and 101 in the 5FU + IFNapha-2a arm) were included in the final intention-to-treat analysis. Rectal cancers were not considered eligible. All patients had measurable disease, were…

MaleAntimetabolites AntineoplasticCancer Researchmedicine.medical_specialtyColorectal cancerAlpha interferonInterferon alpha-2GastroenterologyMetastasisInternal medicineAntineoplastic Combined Chemotherapy ProtocolsmedicineCarcinomaHumansInterferon alfaAgedLeukopeniabusiness.industryStandard treatmentInterferon-alphaGeneral MedicineMiddle Agedmedicine.diseaseRecombinant ProteinsSurgeryOncologyFluorouracilColonic NeoplasmsFemaleFluorouracilmedicine.symptombusinessmedicine.drugJournal of Cancer Research and Clinical Oncology
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“I tumori di origine sconosciuta”

2004

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”L’associazione di gemcitabina e docetaxel nel trattamento del carcinoma mammario metastatico”

2004

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