0000000000009526

AUTHOR

Sandrine Dabakuyo-yonli

showing 2 related works from this author

An explorative study to assess the association between health-related quality of life and the recommended phase II dose in a phase I trial: idarubici…

2016

Objectives The objective of this study was to explore the association between health-related quality of life (HRQoL) and the recommended phase 2 dose in a phase I clinical trial according to the Time to HRQoL deterioration approach (TTD). Setting This is a phase I dose-escalation trial of transarterial chemoembolisation (TACE) with idarubicin-loaded beads performed in cirrhotic patients with hepatocellular carcinoma. Patients had to complete the EORTC QLQ-C30 HRQoL questionnaire at baseline and at days 15, 30 and 60 after TACE. Participants Patients aged ≥18 years with HCC unsuitable for curative treatments were evaluated for the study (N=21). Primary and secondary outcome measurements The …

MaleOncologyHealth-related Quality of LifePhases of clinical research[ SDV.CAN ] Life Sciences [q-bio]/Cancer0302 clinical medicineQuality of life1506FatigueAntibiotics AntineoplasticLiver NeoplasmsGeneral MedicineMiddle Aged3. Good healthOncology030220 oncology & carcinogenesisHepatocellular carcinomaToxicityFemale[ SDV.MHEP.HEG ] Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology030211 gastroenterology & hepatology1717medicine.drugmedicine.medical_specialtyCarcinoma HepatocellularMaximum Tolerated Dose1722Pain[SDV.CAN]Life Sciences [q-bio]/CancerPhase 1Disease-Free Survival03 medical and health sciencesInternal medicineCarcinomamedicineHumansIdarubicinChemoembolization TherapeuticAgedHealth-related Quality of ifeOncology clinical trialHealth related quality of lifebusiness.industryResearchlongitudinal analysis[SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterologyphase Imedicine.diseaseSurgeryTime to deteriorationMaximum tolerated doseQuality of LifeIdarubicinbusinessBMJ Open
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How do age and social environment affect the dynamics of death hazard and survival in patients with breast or gynecological cancer in France?

2021

Several studies have investigated the association between net survival and social inequalities in people with cancer, highlighting a varying influence of deprivation depending on the type of cancer studied. However, few of these studies have accounted for the effect of social inequalities over the follow-up period, and/or according to the age of the patients. Thus, using recent and more relevant statistical models, we investigated the effect of social environment on net survival in women with breast or gynecological cancer in France. The data were derived from population-based cancer registries, and women diagnosed with breast or gynecological cancer between 2006 and 2009 were included. We …

AdultCancer ResearchDeprivationGenital Neoplasms FemalePopulationBreast NeoplasmsAffect (psychology)03 medical and health sciencesNet survival0302 clinical medicineBreast cancerBreast cancerMedicineHumansSocial inequality030212 general & internal medicineRegistrieseducationAgedCervical cancerAged 80 and overeducation.field_of_studybusiness.industryAge FactorsSocial environmentCancerMiddle Agedmedicine.diseasePrognosis3. Good healthSurvival RateSocial environmentOncologySocioeconomic Factors030220 oncology & carcinogenesisGynecological cancerFemale[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieFrancebusinessOvarian cancerDemographyFollow-Up Studies
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