Synthesis of New Pyrazole Derivatives as Potential CDK1 Inhibitors

An international assessment of the adoption of enhanced recovery after surgery (ERAS®) principles across colorectal units in 2019–2020

Aim The Enhanced Recovery After Surgery (ERAS® ) Society guidelines aim to standardise perioperative care in colorectal surgery via 25 principles. We aimed to assess the variation in uptake of these principles across an international network of colorectal units. Method An online survey was circulated amongst European Society of Coloproctology members in 2019/20. For each ERAS® principle, respondents were asked to score how frequently the principle was implemented in their hospital, from 1 ('rarely') to 4 ('always'). Respondents were also asked to recall whether practice had changed since 2017. Subgroup analyses based on hospital characteristics were conducted. Results Of hospitals approache…

Correction: ERas and COLorectal endoscopic surgery: an Italian society for endoscopic surgery and new technologies (SICE) national report (Surgical Endoscopy, (2022), 10.1007/s00464-022-09212-y)

This article was updated to correct Nicolò Fabbri's name in the listing of the ERCOLE Study Group (in Acknowledgments).

Intraperitoneal drain placement and outcomes after elective colorectal surgery: International matched, prospective, cohort study

Abstract Background Many surgeons routinely place intraperitoneal drains after elective colorectal surgery. However, enhanced recovery after surgery guidelines recommend against their routine use owing to a lack of clear clinical benefit. This study aimed to describe international variation in intraperitoneal drain placement and the safety of this practice. Methods COMPASS (COMPlicAted intra-abdominal collectionS after colorectal Surgery) was a prospective, international, cohort study which enrolled consecutive adults undergoing elective colorectal surgery (February to March 2020). The primary outcome was the rate of intraperitoneal drain placement. Secondary outcomes included: rate and tim…

Uso agricolo estensivo di suoli salini e recupero, conservazione e valorizzazione della biodiversità nella piana di Gela (CL). L’armonizzazione possibile

Correction to: Mesoglycan for pain control after open excisional HAEMOrrhoidectomy (MeHAEMO): an observational multicentre study on behalf of the Italian Society of Colorectal Surgery (SICCR) (BMC Surgery, (2020), 20, 1, (251), 10.1186/s12893-020-00914-5)

An amendment to this paper has been published and can be accessed via the original article.

Metabolic pathways and regulatory networks associated to NAI-107 lantibiotic production in Microbispora sp. ATCC-PTA-5024

The filamentous actinobacterium Microbispora sp. ATCC-PTA-5024 produces the lantibiotic NAI-107, which is effective against multidrugresistant Gram-positive pathogens. In actinomycetes, the biosynthesis of antibiotics is elicited as a physiological response that is controlled by a complex regulatory network involving general and pathwayspecific regulators. The ‘omics technologies can be useful to explore molecular physiology in bacterial cells and elucidate molecular and metabolic events associated to antibiotic production in order to develop robust and economically-feasible production processes. To this aim, differential proteomic analyses, based two-dimensional difference in gel electroph…

FORENSIC ANALYSIS OF SAMPLES OF CONFISCATED ABUSE SUBSTANCES, CARRIED OUT IN THE LABORATORY OF ANALYSIS AND DRUGS OF THE CARABINIERI, MILITARY STATION “CARINI”, PALERMO

The aim of this study was to define some methods of qualitative and quantitative analysis for technical verification of alleged drugs confiscated by the stations of the Carabinieri in Palermo and Trapani provinces. Observation concerned: the quantity of the confiscated material, the quantity of the active principle, the cutting substances and the consumption in adult and minor population. The Carabinieri ask for analyses of confiscated drugs to the L.A.S.S. laboratory, where the samples are added with the suitable standard and put to ultrasound. Then, the solution is analyzed with gas cromatography and gas mass spectrometry. In 2015 there were 1,000 analysed finds out of 1,454 total finds. …

Polysaccharide-based ionogels as sustainable antioxidant and antimicrobial materials

Evaluation and management of hemorrhoids: Italian society of colorectal surgery (SICCR) consensus statement

Hemorrhoidal disease (HD) is the most common proctological disease in the Western countries. However, its real prevalence is underestimated due to the frequent self-medication. The aim of this consensus statement is to provide evidence-based data to allow an individualized and appropriate management and treatment of HD. The strategy used to search for evidence was based on application of electronic sources such as MEDLINE, PubMed, Cochrane Review Library, CINAHL, and EMBASE. These guidelines are inclusive and not prescriptive. The recommendations were defined and graded based on the current levels of evidence and in accordance with the criteria adopted by American College of Chest Physician…

Inorganic phosphate limitation affects global gene expression in Amycolatopsis balhimycina

Correction to: Changes in surgicaL behaviOrs dUring the CoviD-19 pandemic. The SICE CLOUD19 Study (Updates in Surgery, (2021), 73, 2, (731-744), 10.1007/s13304-021-01010-w)

The Collaborative Group there are two authors names are incorrect. The correct names are provided below: Paolo Pietro Bianchi and Giampaolo Formisano Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is …