Neuroproteomics in the auditory brainstem: candidate proteins for ultrafast and precise information processing.

In the mammalian auditory brainstem, the cochlear nuclear complex (CN) and the superior olivary complex (SOC) feature structural and functional specializations for ultrafast (<1 ms) and precise information processing. Their proteome, the basis for structure and function, has been rarely analyzed so far. Here we identified and quantified the protein profiles of three major auditory brainstem regions of adult rats, the CN, the SOC, and the inferior colliculus (IC). The rest of the brain served as a reference. Via label-free quantitative mass spectrometry and 2-D DIGE/MALDI-MS, we identified 584 and 297 proteins in the plasma membrane/synaptic vesicle proteome and the cytosolic proteome, respe…

Erratum to “Neuroproteomics in the auditory brainstem: Candidate proteins for ultrafast and precise information processing” [Mol. Cell. Neurosci. (64), pages 9–23]