Author: Alexia García-serran

0000000000020664

AUTHOR

Alexia García-serran

0000-0003-1630-1302

showing 1 related works from this author

Comparative Proteomics Unveils LRRFIP1 as a New Player in the DAPK1 Interactome of Neurons Exposed to Oxygen and Glucose Deprivation

2020

Altres ajuts: The group has received funding from 'la Caixa Foundation' CI15-00009, from the European Institute of Innovation and Technology (EIT) PoC-2016-SPAIN-04, which receives support from the European Union's Horizon 2020 research and innovation program, and from the 'Fundación para la Innovación y la Prospectiva en Salud en España (FIPSE)' program 3594-18. Death-associated protein kinase 1 (DAPK1) is a pleiotropic hub of a number of networked distributed intracellular processes. Among them, DAPK1 is known to interact with the excitotoxicity driver NMDA receptor (NMDAR), and in sudden pathophysiological conditions of the brain, e.g., stroke, several lines of evidence link DAPK1 with t…

0301 basic medicinePhysiologyClinical BiochemistryExcitotoxicitymedicine.disease_causeProteomicsBiochemistryInteractomeNeuroprotectionArticle03 medical and health sciences0302 clinical medicinemedicineDAPK1Protein kinase AMolecular Biologychemistry.chemical_classificationReactive oxygen specieslcsh:RM1-950OGDROSCell BiologyneuronferroptosisCell biology030104 developmental biologymedicine.anatomical_structurelcsh:Therapeutics. Pharmacologychemistrynervous systemNMDANeuronLRRFIP1MCAO030217 neurology & neurosurgeryIntracellularAntioxidants

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