0000000000021768
AUTHOR
N. Kurjane
<title>Micro-Raman scattering and infrared spectra of hemoglobin</title>
Confocal micro-Raman and FT-IR spectroscopies have been used for detection of radiation influence of hemoglobin of patients examined by radio-isotopes diagnosis (Tc99m). After irradiation we observed some little changes of the Raman scattering bands which connected with out of plane porphyrine bending vibrations, also we observed additional band due to methemoglobin. Radiation of blood lead to the transition from hemoglobin (Fe2+) to methemoglobin (Fe3+) with a delocalization of iron from porphyrine plane. It was shown that FT-IR spectra indicate the radiation effects on hemoglobin.© (2008) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is per…
Chernobyl Clean-Up Workers: 17 Years of Follow-Up in Latvia
About 5000 Latvian inhabitants took part at clean up works after accident on Chernobyl Nuclear Power Plant during 1986–1991. Clinical follow-up programme showed that clean-up workers having higher morbidity rate compare to the general population with prevalence of poly–symptomatic sicknesses caused by depression of immune system. Dose reconstruction made by Electron Paramagnetic Resonance (EPR) indicated underestimation of officially documented doses by factor 2-10. Blood measurement performed by Inductively Coupled Plasma Mass Spectrometry (ICP MS) indicated elevated concentration of lead, cadmium and thorium. It was assumed that toxic compounds, physical stress, incorporated long-lived ra…
The Optical And Epr Spectra of Fe(2+) and Fe(3+) Ions in the Blood of the Chernobyl Clean-Up Worker
Electron paramagnetic resonance (EPR) and optical absorption studies of blood were provided for the group of Chernobyl’s NPP accident clean-up workers examined in the Center of Occupational and Radiological medicine of P.Stradins Clinical hospital of Medical Academy of Latvia. The EPR spectra for blood have been studied at low temperature. It is shown that in blood the ion Fe3+ of methemaglobin is in low-spin state with g = 2.3 and in the high spin state with g=6. We observed the additional absorption bands 500 nm (shoulder) and 630 nm in absorption spectra of blood of Chernobyl clean-up worker who has erythrocytosis.
Analysis of the Immune Status in Latvian Chernobyl Clean-up Workers with Nononcological Thyroid Diseases
The aim of the present work was to characterize the immune status of 385 individuals who participated in the 1986–90 clean-up work of the after effects of the Chernobyl nuclear power plant explosion. Fifty-nine Chernobyl clean-up workers developed the most common thyroid diseases; euthyroid nodular and diffuse goiter; 47 healthy blood donors were taken as controls. The levels of immunoglobulins (IgA, IgG and IgM), the numbers of peripheral blood leukocytes, lymphocytes, monocytes, T lymphocytes and their subpopulations (CD3+, CD4+, CD8+), B lymphocytes (CD19+), natural killer (NK) cells (CD16+), classical and alternative pathway activity of complement (CH50, APH50), the C3 split product C3d…