0000000000022112

AUTHOR

Vlaho Brailo

showing 4 related works from this author

Evaluation of pretreatment serum interleukin-6 and tumour necrosis factor alpha as a potential biomarker for recurrence in patients with oral squamou…

2014

Background Oral squamous cell carcinoma (OSCC) constitutes 3 percent of all cancers with predominant occurrence in middle aged and elderly males. Tumour recurrence worsens disease prognosis and decreases quality of life in patients with OSCC. Proinflammatory cytokines such as interleukin-6 (IL-6) and tumour necrosis factor alpha (TNF-α) have been suggested to play a certain role in variety of tumours. The aim of this study was to investigate the relationship of pretreatment serum IL-6 and TNF-α levels on tumour recurrence in patients with OSCC in order to identify potential biomarkers for the early detection of disease recurrence. Material and Methods The patients with newly diagnosed OSCC …

OncologyAdultMalemedicine.medical_specialtyPathologyOdontología03 medical and health sciences0302 clinical medicineRisk FactorsInternal medicinemedicineCarcinomaSerum IL-6 ; serum TNF-α ; oral cancer ; recurrenceBiomarkers TumorHumansProspective StudiesRisk factorProspective cohort studyGeneral DentistrySurvival analysisEarly Detection of CancerAgedMouth neoplasmOral Medicine and Pathologybusiness.industryInterleukin-6Tumor Necrosis Factor-alphaResearchCancer030206 dentistryMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Ciencias de la salud3. Good healthLog-rank teststomatognathic diseasesOtorhinolaryngology030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASCarcinoma Squamous CellBiomarker (medicine)SurgeryFemaleMouth NeoplasmsNeoplasm Recurrence LocalbusinessMedicina oral, patologia oral y cirugia bucal
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Oral lichen planus – retrospective study of 563 Croatian patients

2014

Objectives were to evaluate sociodemographic and clinical data of oral lichen planus (OLP) patients attending our Department from 2006.-2012. Retrospective chart review was performed. Data regarding age, gender, medical history, drugs, smoking, alcohol, chief complaint, clinical type, localization, histology, treatment and malignant transformation were registered for 563 patients. Majority of patients were female (414 ; 73.5%) and median age was 58 (range 11-94). Majority of patients did not smoke (408 ; 72.5%) and did not consume alcohol (392 ; 69.6%). Chief complaint was oral soreness (242 ; 43.3%) followed by mucosal roughness (39 ; 7%), xerostomia (17 ; 3%), gingival bleeding (11 ; 2%) …

AdultMalemedicine.medical_specialtyAdolescentCroatiaOdontologíaAsymptomaticMalignant transformationYoung Adultoral lichen planus; malignant transformationstomatognathic systemEpidemiologymedicineHumansMedical historyYoung adultGeneral DentistryAgedRetrospective StudiesAged 80 and overOral Medicine and Pathologybusiness.industryResearchRetrospective cohort studyHistologyMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]DermatologyCiencias de la saludSurgeryoral lichen planus ; malignant transformation ; retrospective studystomatognathic diseasesOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASSurgeryOral lichen planusFemalemedicine.symptombusinessLichen Planus OralMedicina Oral, Patología Oral y Cirugía Bucal
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Salivary and serum levels of substance p, neurokinin A and calcitonin gene related peptide in burning mouth syndrome

2009

Background: Burning mouth syndrome (BMS) is an enigmatic condition with the etiopathogenesis remaining largely obscure. However, a neuropathic basis for BMS continues to be an area of active clinical and research interest. Aim: It is becoming increasingly evident that certain oral disorders may be modulated by imbalances in certain neuropeptides such as substance P (SP), neurokinin A (NKA) and calcitonin gene-related peptide (CGRP) therefore we measured SP, NKA and CGRP in the saliva and sera of BMS patients as well as controls. Subjects and Methods: Salivary and serum SP, NKA and CGRP were determined in the 26 female patients with burning mouth syndrome (age range 51-78, mean 65.69 yrs), a…

Malemedicine.medical_specialtySalivaCalcitonin Gene-Related PeptideNeurokinin ANeuropeptideSubstance PBurning Mouth SyndromeCalcitonin gene-related peptideSubstance Pchemistry.chemical_compoundInternal medicinemedicineHumansSalivaGeneral DentistryAgedbusiness.industryDopaminergicBurning mouth syndromeMiddle Agedrespiratory system:CIENCIAS MÉDICAS [UNESCO]stomatognathic diseasesEndocrinologyOtorhinolaryngologychemistryCalcitoninUNESCO::CIENCIAS MÉDICASSubstance P ; neurokinin A ; calcitonin gene-related peptide ; burning mouth syndromeSurgeryFemaleNeurokinin Amedicine.symptombusiness
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Oral burning symptoms and burning mouth syndrome-significance of different variables in 150 patients

2006

Objectives: Despite the extensive amount of published literature upon burning symptoms in patients with clinically healthy appearance of the oral mucosa, as well as burning mouth syndrome (BMS) itself, they both remain still challenging topics. The aim of this study was to determine the real prevalence of ?true? BMS in comparison to other patients with burning symptoms with clinically healthy appearance of the oral mucosa and then to compare ?true? BMS patients with healthy controls regarding gastritis and intake of anxiolytics and angiotensin converting enzyme inhibitors. Study design: In 150 patients with burning symptoms of clinically healthy oral mucosa, local and systemic investigation…

stomatognathic diseasesUNESCO::CIENCIAS MÉDICAS:CIENCIAS MÉDICAS [UNESCO]
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