0000000000022725

AUTHOR

Marc Heidorn

showing 3 related works from this author

Abstract 13812: Pulmonary Function Predicts Cardiac Function, Structure & Clinical Outcome in Chronic Heart Failure: Results From the Myovasc Stu…

2020

Introduction: A growing body of evidence suggests a relevance of pulmonary function in the pathophysiology of heart failure (HF). Comprehensive data on the role of forced expiratory volume in 1 second (FEV1) in the development & progression of HF is limited. Hypothesis: Given this background, we hypothesized, that (FEV1) is associated with deteriorated left ventricular (LV) functional as well as structural status, & predicts specific clinical outcome in HF. Methods: Data from the MyoVasc Study (n=3,289) were analysed. Comprehensive clinical phenotyping including body plethysmography for the evaluation of FEV1 & standardized echocardiography were performed during a five-hour inv…

Cardiac function curvemedicine.medical_specialtybusiness.industrymedicine.diseaseOutcome (game theory)PathophysiologyPulmonary function testingPhysiology (medical)Internal medicineHeart failureEpidemiologyCardiologymedicineCardiology and Cardiovascular MedicinebusinessCirculation
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FEV1 Predicts Cardiac Status and Outcome in Chronic Heart Failure

2022

Background COPD is an established predictor of clinical outcome in patients with chronic heart failure (HF). However, little evidence is available about the predictive value of FEV1 in chronic HF. Research Question Is pulmonary function related to the progression of chronic HF? Study Design and Methods The MyoVasc study ( ClinicalTrials.gov Identifier: NCT04064450) is a prospective cohort study of HF. Information on pulmonary and cardiac functional and structural status was obtained by body plethysmography and echocardiography. The primary study end point was worsening of HF. Results Overall 2,998 participants (age range, 35-84 years) with available FEV1 data were eligible for analysis. Lin…

Pulmonary and Respiratory MedicineCardiac function curvemedicine.medical_specialtyCOPDEjection fractionbusiness.industryDiastoleCritical Care and Intensive Care Medicinemedicine.diseasePulmonary function testingInternal medicineHeart failureCardiologyMedicineCardiology and Cardiovascular MedicinebusinessHeart failure with preserved ejection fractionProspective cohort studyChest
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Association of Global Longitudinal Strain With Clinical Status and Mortality in Patients With Chronic Heart Failure.

2021

IMPORTANCE: Global longitudinal strain (GLS) is an emerging echocardiographic biomarker of cardiac function in heart failure (HF). Evidence from large-scale studies comprehensively investigating GLS for its association with clinical phenotypes and mortality in asymptomatic and symptomatic chronic HF is limited. OBJECTIVE: To assess the factors associated with GLS and its prognostic value in patients with chronic HF. DESIGN, SETTING, AND PARTICIPANTS: The observational, prospective MyoVasc cohort study enrolled 3289 individuals with asymptomatic to symptomatic HF between January 17, 2013, and April 27, 2018. The median follow-up was 3.2 years (interquartile range, 2.0-4.0 years). Participant…

Cardiac function curveMalemedicine.medical_specialty030204 cardiovascular system & hematologyAsymptomatic03 medical and health sciences0302 clinical medicineInterquartile rangeInternal medicinemedicineHumans030212 general & internal medicineMyocardial infarctionProspective StudiesAgedOriginal InvestigationHeart Failurebusiness.industryHazard ratioPatient AcuityAtrial fibrillationHeartMiddle Agedmedicine.diseasePrognosisEchocardiographyHeart failureFemalemedicine.symptomCardiology and Cardiovascular MedicinebusinessBiomarkersCohort studyJAMA cardiology
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