0000000000023250

AUTHOR

Vincenzo Novara

showing 2 related works from this author

Antidepressant and anxiolytic effects of alprazolam versus the conventional. antidepressant desipramine and the anxiolytic diazepam in the forced swi…

1992

The antidepressant and anxiolytic effects of alprazolam were compared to those of desipramine, diazepam and buspirone in the forced swim test. Subchronic alprazolam induced a reduction in immobility similar to that of desipramine in 'non-pretested' and 'pretested' rats. In 'non-pretested' rats, the anti-immobility effect of desipramine was potentiated by diazepam and alprazolam, given before subchronic desipramine, while the anti-immobility effect of subchronic alprazolam was counteracted by diazepam. Diazepam, administered before the pretest session, counteracted, 24 h later, the anti-immobility effect of subchronic desipramine and alprazolam; alprazolam counteracted the anti-immobility ef…

Malemedicine.drug_classPharmacologyAnxiolyticBuspironeDesipraminemedicineAnimalsSwimmingPharmacologyBenzodiazepineDiazepamAlprazolamDepressionDesipramineRats Inbred StrainsReceptors GABA-AAntidepressive AgentsBuspironeRatsAnti-Anxiety AgentsAlprazolamReceptors SerotoninAntidepressantPsychologyDiazepamBehavioural despair testmedicine.drugEuropean Journal of Pharmacology
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Investigation and management of Toxoplasma gondii infection in pregnancy and infancy: a prospective study.

2011

Aim:Toxoplasma gondii infection during pregnancy poses a serious risk to the fetus, therefore timely and accurate diagnosis is essential. The aim of this study was to estimate the frequency of congenital infection via evaluating mother's immunological status and the possibility to improving the diagnostic and therapeutic approaches.Methods:Eighty five mothers with Toxoplasma seroconversion and their offspring were enrolled (among them, 2 spontaneous abortions were documented in the first trimester). Prenatal PCR diagnosis was carried out on 50 patients (60%), with 7 positive cases (14%). Morphological ultrasound scanning revealed anomalies in one fetus. Long-term follow-up included general …

medicine.medical_specialtySettore MED/17 - Malattie InfettiveOffspringToxoplasmosis gondiineurological prognosiToxoplasmosis CongenitalSerologySettore MED/38 - Pediatria Generale E SpecialisticaPregnancyPrenatal DiagnosismedicineHumansPharmacology (medical)Prospective StudiesSeroconversionProspective cohort studyChildPharmacologyFetusPregnancybiologybusiness.industryObstetricsSettore MED/30 - Malattie Apparato Visivoocular prognosiPregnancy OutcomeToxoplasma gondiiGeneral Medicinemedicine.diseasebiology.organism_classificationToxoplasmosisInfectious Disease Transmission Verticalcongenital infectionWestern blot analysisprenatal screeningChild PreschoolPregnancy Complications ParasiticImmunologyserological responseFemaleOriginal ArticlebusinessFollow-Up StudiesActa pharmacologica Sinica
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