0000000000023928
AUTHOR
E. Soria-olivas
Manual motor speed dysfunction as a neurocognitive endophenotype in euthymic bipolar disorder patients and their healthy relatives. Evidence from a 5-year follow-up study
Background: Few studies have examined Manual Motor Speed (MMS) in bipolar disorder (BD). The aim of this longitudinal, family study was to explore whether dysfunctional MMS represents a neurocognitive endophenotype of BD. Methods: A sample of 291 subjects, including 131 BD patients, 77 healthy first-degree relatives (BD-Rel), and 83 genetically-unrelated healthy controls (HC), was assessed with the Finger-Tapping Test (En) on three occasions over a 5-year period. Dependence of FTT on participants' age was removed by means of a lineal model of HC samples, while correcting simultaneously the time and learning effect. Differences between groups were evaluated with an ANOVA test. Results: The p…
Robust g-filter using support vector method
This Letter presents a new approach to time series modelling using the support vector machines (SVM). Although the g filter can provide stability in several time series models, the SVM is proposed here to provide robustness in the estimation of the g filter coefficients. Examples in chaotic time series prediction and channel equalization show the advantages of the joint SVM g filter. Publicado