0000000000025568

AUTHOR

Sandra Philipp

showing 3 related works from this author

S2k guidelines for the treatment of psoriasis in children and adolescents - Short version part 1.

2019

The present guidelines are aimed at residents and board-certified physicians in the fields of dermatology, pediatrics, pediatric dermatology and pediatric rheumatology as well as policymakers and insurance funds. They were developed by dermatologists and pediatric dermatologists in collaboration with pediatric rheumatologists using a formal consensus process (S2k). The guidelines highlight topics such as disease severity, quality of life, treatment goals as well as problems associated with off-label drug therapy in children. Trigger factors and diagnostic aspects are discussed. The primary focus is on the various topical, systemic and UV-based treatment options available and includes recomm…

medicine.medical_specialtyConsensusAdolescentUltraviolet RaysAdministration TopicalMEDLINEDiseaseComorbidityDermatologySeverity of Illness Index030207 dermatology & venereal diseases03 medical and health sciencesPsoriatic arthritis0302 clinical medicineQuality of life (healthcare)PharmacotherapyRheumatologyPsoriasisSeverity of illnessmedicineHumansPsoriasisIntensive care medicineChildbusiness.industryArthritis PsoriaticInfant NewbornInfantOff-Label Usemedicine.diseaseChild PreschoolPractice Guidelines as TopicQuality of LifebusinessGuttate psoriasisJournal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDGReferences
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S2k guidelines for the treatment of psoriasis in children and adolescents - Short version part 2.

2019

The present guidelines are aimed at residents and board-certified physicians in the fields of dermatology, pediatrics, pediatric dermatology and pediatric rheumatology as well as policymakers and insurance funds. They were developed by dermatologists and pediatric dermatologists in collaboration with pediatric rheumatologists using a formal consensus process (S2k). The guidelines highlight topics such as disease severity, quality of life, treatment goals as well as problems associated with off-label drug therapy in children. Trigger factors and diagnostic aspects are discussed. The primary focus is on the various topical, systemic and UV-based treatment options available and includes recomm…

medicine.medical_specialtyTuberculosisAdolescentMEDLINEDermatologyDiseaseDrug Administration Schedule030207 dermatology & venereal diseases03 medical and health sciencesPsoriatic arthritisBiological Factors0302 clinical medicinePharmacotherapyQuality of life (healthcare)PsoriasismedicineHumansPsoriasisChildBiosimilar PharmaceuticalsTonsillectomybusiness.industryVaccinationmedicine.diseaseSkin CareAnti-Bacterial AgentsFamily medicineUltraviolet TherapyDermatologic AgentsbusinessGuttate psoriasisImmunosuppressive AgentsJournal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDGReferences
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Skin Sodium Accumulates in Psoriasis and Reflects Disease Severity

2020

Sodium can accumulate in the skin at concentrations exceeding serum levels. A high sodium environment can lead to pathogenic T helper 17 cell expansion. Psoriasis is a chronic inflammatory skin disease in which IL-17. producing T helper 17 cells play a crucial role. In an observational study, we measured skin sodium content in patients with psoriasis and in age-matched healthy controls by Sodium-23 magnetic resonance imaging. Patients with PASI > 5 showed significantly higher sodium and water content in the skin but not in other tissues than those with lower PASI or healthy controls. Skin sodium concentrations measured by Sodium-23 spectroscopy or by atomic absorption spectrometry in ashed-…

Malemedicine.medical_specialtySodiumchemistry.chemical_elementInflammationImiquimodDermatologySodium ChlorideLymphocyte ActivationSeverity of Illness IndexBiochemistryArticleMiceInternal medicinePsoriasismedicineExtracellularAnimalsHumansPsoriasisT helper 17 cellMolecular BiologyCells CulturedSkinintegumentary systembusiness.industrySpectrophotometry AtomicSpectrum AnalysisInterleukin-17SodiumCell DifferentiationCell Biologymedicine.diseasePathophysiologyMice Inbred C57BLEndocrinologychemistryCardiovascular and Metabolic DiseasesTh17 Cellsmedicine.symptombusinessIntracellularmedicine.drugJournal of Investigative Dermatology
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