0000000000025952

AUTHOR

Christian Agard

showing 3 related works from this author

Reducing the initial number of rituximab maintenance-therapy infusions for ANCA-associated vasculitides: randomized-trial post-hoc analysis

2020

AbstractObjectiveThe randomized, controlled MAINRITSAN2 trial was designed to compare the capacity of an individually tailored therapy [randomization day 0 (D0)], with reinfusion only when CD19+ lymphocytes or ANCA had reappeared, or if the latter’s titre rose markedly, with that of five fixed-schedule 500-mg rituximab infusions [D0 + D14, then months (M) 6, 12 and 18] to maintain ANCA-associated vasculitis (AAV) remissions. Relapse rates did not differ at M28. This ancillary study was undertaken to evaluate the effect of omitting the D14 rituximab infusion on AAV relapse rates at M12.MethodsMAINRITSAN2 trial data were subjected to post-hoc analyses of M3, M6, M9 and M12 relapse-free surviv…

medicine.medical_specialtyRandomizationAntigens CD19Anti-Neutrophil Cytoplasmic Antibody-Associated VasculitisGastroenterologyDisease-Free SurvivalDrug Administration ScheduleAntibodies Antineutrophil CytoplasmicMaintenance Chemotherapylaw.invention03 medical and health sciences0302 clinical medicineRheumatologyMaintenance therapyRandomized controlled triallawInternal medicinePost-hoc analysismedicineHumansPharmacology (medical)030212 general & internal medicineSurvival rate030203 arthritis & rheumatologybusiness.industrymedicine.diseaseAntirheumatic AgentsRituximabRituximabMicroscopic polyangiitisGranulomatosis with polyangiitisbusinessmedicine.drugRheumatology
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Management of giant cell arteritis: Recommendations of the French Study Group for Large Vessel Vasculitis (GEFA).

2016

Abstract Purpose Management of giant cell arteritis (GCA, Horton's disease) involves many uncertainties. This work was undertaken to establish French recommendations for GCA management. Methods Recommendations were developed by a multidisciplinary panel of 33 physicians, members of the French Study Group for Large Vessel Vasculitis (Groupe d’etude francais des arterites des gros vaisseaux [GEFA]). The topics to be addressed, selected from proposals by group members, were assigned to subgroups to summarize the available literature and draft recommendations. Following an iterative consensus-seeking process that yielded consensus recommendations, the degree of agreement among panel members was…

medicine.medical_specialtyConsensusConsensus Development Conferences as TopicGiant Cell ArteritisDiseaseRecommendations03 medical and health sciences0302 clinical medicineLarge vessel vasculitisDiagnosismedicineInternal MedicineHumans030212 general & internal medicineIntensive care medicineExpert TestimonySocieties Medical030203 arthritis & rheumatologyModalitiesbusiness.industryBiologic therapiesGastroenterologyTemporal artery biopsymedicine.diseaseSurgeryTreatmentGiant cell arteritisRegimenAdjunctive treatmentCommittee MembershipFrancebusinessAlgorithmsLa Revue de medecine interne
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Giant cell arteritis-related aortitis with positive or negative temporal artery biopsy: a French multicentre study.

2019

Objective: To compare the clinical presentation and outcome of giant cell arteritis (GCA)-related aortitis according to the results of temporal artery biopsy (TAB).Method: Patients with GCA-related...

Malemedicine.medical_specialtyBiopsyImmunologyGiant Cell Arteritis03 medical and health sciences0302 clinical medicineRheumatologyimmune system diseasesmedicineImmunology and AllergyHumanscardiovascular diseases030212 general & internal medicineskin and connective tissue diseasesAortitisAgedRetrospective Studies030203 arthritis & rheumatologyAortitisbusiness.industryGeneral MedicineTemporal artery biopsyMiddle Agedmedicine.diseaseTemporal ArteriesGiant cell arteritiscardiovascular systemFemaleRadiologyPresentation (obstetrics)businessTomography X-Ray ComputedScandinavian journal of rheumatology
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