Sentinel Lymph Node Analysis in Colorectal Cancer Patients Using One-Step Nucleic Acid Amplification in Combination With Fluorescence and Indocyanine Green
Purpose: Analysis of the sentinel lymph node (SLN) in colorectal cancer (CRC) patients was proposed for more accurate staging and tailored lymphadenectomy. The aim of this study was to assess the ability to predict lymph node (LN) involvement through analysis of the SLN with a one-step nucleic acid (OSNA) technique in combination with peritumoral injection of indocyanine green (ICG) and near-infrared (NIR) lymphangiography in CRC patients. Methods: A total of 34 patients were enrolled. Overall, 51 LNs were analyzed with OSNA. LNs of 17 patients (50%) were examined simultaneously with hematoxylin and eosin (H&E) and OSNA. Results: SLN analysis of 17 patients examined with H&E and OSN…
Emergency abdominal surgery after solid organ transplantation: a systematic review
Aims: Due to the increasing number of solid organs transplantations, emergency abdominal surgery in transplanted patients is becoming a relevant challenge for the general surgeon. The aim of this systematic review of the literature is to analyze morbidity and mortality of emergency abdominal surgery performed in transplanted patients for graft-unrelated surgical problems. Methods: The literature search was performed on online databases with the time limit 1990–2015. Studies describing all types of emergency abdominal surgery in solid organ transplanted patients were retrieved for evaluation. Results: Thirty-nine case series published between 1996 and 2015 met the inclusion criteria and were…
Coupling of Structural Additions for the Mitigation of Seismic Response in Existing Buildings
In the present paper, additions in structural steelwork are utilized for giving new life to old buildings in regions characterized by medium/high seismic hazard. Two models are here proposed, i.e.: vertical addition for masonry buildings and lateral addition for r.c. buildings. For the model of vertical addition, the connection between the masonry and steel structures is realized by means of an Intermediate Isolation System (IIS). For the model of lateral addition, an exoskeleton (EXO) is connected to the existing building by means of rigid or flexible and dissipative link. Two buildings, representative of the heterogeneous Italian building stock, are selected as case studies. Parametric an…
Incidence and predictors of portal and splenic vein thrombosis after pure laparoscopic splenectomy.
Background. Optimal modalities for diagnosis, treatment, and surveillance of portal or splenic vein thrombosis have not yet been defined. The present retrospective study aimed to investigate the role of computed tomography performed systematically before and after laparoscopic splenectomy to assess the incidence of portal or splenic vein thrombosis, predictors, and outcomes. Methods. Computed tomography scans were obtained from 170 patients undergoing elective laparoscopic splenectomy between 2005 and 2015. Pre- and postoperative splenic vein diameter was measured at the splenoportal junction and at a distance of 2, 4, 6 cm from it. Univariate and multivariate analyses were used to identify…
Up-to-date imaging review of paediatric soft tissue vascular masses, focusing on sonography
The purpose of this article is to provide an up-to-date overview on imaging of paediatric vascular soft tissue masses, including both neoplastic and non-neoplastic lesions. We describe the-often challenging-imaging diagnosis-mainly performed by ultrasound (and secondarily by MRI) and differential diagnosis of vascular soft tissue lesions in children. We underline how important it is to determine whether a vascular anomaly has a regional vascular origin, or if there are other entities, ranging from benign to malignant lesions, which have flow-signal or blood degradation products. Even though clinical examination and patient's history are the first and indispensable steps in the initial diagn…
Intermediate Isolation System with Nonlinear Lower Structure and Isolation System
This paper reports a study on the Intermediate Isolation System (IIS) applied to existing buildings. This kind of application is particularly suitable when a vertical addition is planned for buildings in seismic zones; in such a case, an isolation system can be placed at the base of the extension to prevent the increase, or, better, to reduce the seismic demand on the existing structure. In previous works, parametric response spectrum analyses have been carried out on lumped mass models by varying the period of the isolation system. As a result, a sort of IIS design spectrum has been derived and used for selecting design solutions for the vertical extension that minimize the overall seismic…
Solitary splenic metastasis from nasopharyngeal carcinoma: a case report and systematic review of the literature
Background: Solitary splenic metastases are a rare occurrence, and the nasopharyngeal carcinoma represents one of the most uncommon primary sources. The present study aimed to describe a rare case of a solitary single splenic metastasis from nasopharyngeal carcinoma and to assess the number of cases of isolated nasopharyngeal carcinoma metastases to the spleen reported in the literature. Main body: We describe the case of a 56-year-old man with a history of nasopharyngeal carcinoma and complete remission after chemo-radiotherapy. Three months after complete remission, positron emission tomography/ computed tomography scan revealed a hypermetabolic splenic lesion without increased metabolic …
The Effect of Nonlinear Response of the Primary System in Nonconventional TMDs
Tuned Mass Dampers (TMD) have been widely used in the passive vibration control of engineering structures, both under wind and seismic loads. Under wind loads, a proper frequency tuning ensures a significant response reduction of the primary structure. While under wind loads the structure is likely to remain in the elastic range of behaviour, when large earthquakes occur it can experience inelastic deformations and damage, with a consequent de-tuning effect. In this paper, nonconventional TMDs with large mass ratios, realized through Interstory Isolation Systems (IIS), are considered and the influence of the inelastic behaviour of the primary system on the overall structure response is anal…