ReALity

Understanding how biological systems maintain long-term stability is the central theme of this initiative. We seek to understand how complex cellular systems react and adapt to existential threats of intrinsic and environmental origins and maintain homeostasis to promote longevity." Why do some people stand stably in their lives, while others are struggling with every day's burden and sometimes even develop mental disease? Why do some individuals maintain mental flexibility into old age, while others are locked in rigid behaviors early in their lives or rapidly develop dementia as they get older? Why is the lifetime incidence of cancer high in some species, while the disease is virtually un…