0000000000033627

AUTHOR

Martin Kruschewski

showing 7 related works from this author

Prävalenz von Alarm-, dyspeptischen und Reflux-Symptomen bei Patienten mit Adenokarzinom des ösophagogastralen Übergangs und Magenkarzinom

2021

Viszeralmedizin 2021 Gemeinsame Jahrestagung Deutsche Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS), Sektion Endoskopie der DGVS, Deutsche Gesellschaft für Allgemein und Viszeralchirurgie (DGAV)
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Magenkarzinom auf dem Boden einer Autoimmungastritis: eine Fall-Kontroll-Studie aus dem staR (gastric cancer research)-Konsortium

2017

72. Jahrestagung der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten mit Sektion Endoskopie – 11. Herbsttagung der Deutschen Gesellschaft für Allgemein- und Viszeralchirurgie gemeinsam mit den Arbeitsgemeinschaften der DGAV
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Mismatch Reparatur Defizienz, Chemotherapie und Überleben bei resektablem Magenkarzinom: Eine Beobachtungsstudie der deutschen Zentren des staR-Proje…

2021

Viszeralmedizin 2021 Gemeinsame Jahrestagung Deutsche Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS), Sektion Endoskopie der DGVS, Deutsche Gesellschaft für Allgemein und Viszeralchirurgie (DGAV)
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Gastric cancer in autoimmune gastritis: A case-control study from the German centers of the staR project on gastric cancer research

2020

Objectives Patients with autoimmune gastritis (AIG) are reported to have an increased risk of developing gastric cancer (GC). In this study, we assess the characteristics and outcomes of GC patients with AIG in a multicenter case-control study. Methods Between April 2013 and May 2017, patients with GC, including cancers of the esophagogastric junction (EGJ) Siewert type II and III, were recruited. Patients with histological characteristics of AIG were identified and matched in a 1:2 fashion for age and gender to GC patients with no AIG. Presenting symptoms were documented using a self-administered questionnaire. Results Histological assessment of gastric mucosa was available for 572/759 GC …

Intrinsic FactorMalemedicine.medical_specialtyAutoimmune Gastritisautoimmune gastritisRisk AssessmentGastroenterologysurvivalAutoimmune DiseasesGerman03 medical and health sciences0302 clinical medicineParietal Cells GastricRisk FactorsStomach NeoplasmsInternal medicineAnemia PerniciousmedicineHumansEndoscopy Digestive SystemAgedAutoantibodiesbiologyHelicobacter pyloribusiness.industryGastroenterologyCase-control studyCancerOriginal ArticlesMiddle AgedHelicobacter pyloribiology.organism_classificationmedicine.diseaselanguage.human_languageIncreased riskOncologyGastric MucosaCase-Control StudiesGastritis030220 oncology & carcinogenesislanguagesymptomsFemale030211 gastroenterology & hepatologybusinessGastric cancerUnited European Gastroenterology Journal
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Evidence for PTGER4, PSCA and MBOAT7 as risk genes for gastric cancer on the genome and transcriptome level

2017

TranscriptomeGeneticsmedicineCancerBiologymedicine.diseaseGeneGenome72. Jahrestagung der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten mit Sektion Endoskopie – 11. Herbsttagung der Deutschen Gesellschaft für Allgemein- und Viszeralchirurgie gemeinsam mit den Arbeitsgemeinschaften der DGAV
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Evidence for PTGER4 ,PSCA, and MBOAT7 as risk genes for gastric cancer on the genome and transcriptome level

2018

Genetic associations between variants on chromosome 5p13 and 8q24 and gastric cancer (GC) have been previously reported in the Asian population. We aimed to replicate these findings and to characterize the associations at the genome and transcriptome level. We performed a fine-mapping association study in 1926 GC patients and 2012 controls of European descent using high dense SNP marker sets on both chromosomal regions. Next, we performed expression quantitative trait locus (eQTL) analyses using gastric transcriptome data from 143 individuals focusing on the GC associated variants. On chromosome 5p13 the strongest association was observed at rs6872282 (P = 2.53 x 10(-04)) and on chromosome …

Male0301 basic medicineCancer ResearchGenotypeQuantitative Trait LocieQTL studyBiologyGPI-Linked ProteinsPolymorphism Single NucleotideGenomeTranscriptome03 medical and health sciencesAntigens NeoplasmStomach NeoplasmsGene expressionmedicineHumansSNPGenetic Predisposition to DiseaseRadiology Nuclear Medicine and imagingGeneGenetic Association StudiesOriginal ResearchCancer BiologyGeneticsGene Expression ProfilingChromosome MappingMembrane ProteinsChromosomeCancermedicine.diseaseNeoplasm ProteinsGene Expression Regulation Neoplastic030104 developmental biologyOncologygenetic association studyCase-Control StudiesExpression quantitative trait locigene expressionChromosomes Human Pair 5FemaleReceptors Prostaglandin E EP4 SubtypeAcyltransferasesChromosomes Human Pair 8Cancer Medicine
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Different Prevalence of Alarm, Dyspeptic and Reflux Symptoms in Patients with Cardia and Non-cardia Gastric Cancer.

2021

Background and Aims: Symptoms of patients with gastric cancer (GC) are often unspecific and differences in symptoms between patients with cardia and non-cardia GC have been poorly investigated. We aimed to characterize symptoms of patients with cardia and non-cardia GC.
 Methods: Patients with cardia (Siewert type II and III) and non-cardia GC were recruited in the German multicenter cohort of the Gastric Cancer Research (staR) study between 2013 and 2017. Alarm, dyspeptic and reflux symptoms at the time of presentation were documented using a self-administered questionnaire.
 Results: A completed self-administered questionnaire was available for 568/759 recruited patients (132 ca…

Malemedicine.medical_specialtyPopulationGastroenterologyWeight lossStomach NeoplasmsInternal medicinemedicinePrevalenceHumansStage (cooking)educationeducation.field_of_studybusiness.industryGastroenterologyRefluxCancerCardiaEndoscopyMiddle Agedmedicine.diseaseDysphagiadigestive system diseasesCohortmedicine.symptombusinessCohort studyJournal of gastrointestinal and liver diseases : JGLD
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