0000000000039710

AUTHOR

Luzius B. Hiltebrand

showing 2 related works from this author

Hemodynamic Parameters Change Earlier Than Tissue Oxygen Tension in Hemorrhage

2010

BACKGROUND: Untreated hypovolemia results in impaired outcome. This study tests our hypothesis whether general hemodynamic parameters detect acute blood loss earlier than monitoring parameters of regional tissue beds. MATERIALS AND METHODS: Eight pigs (23-25 kg) were anesthetized and mechanically ventilated. A pulmonary artery catheter and an arterial catheter were inserted. Tissue oxygen tension was measured with Clark-type electrodes in the jejunal and colonic wall, in the liver, and subcutaneously. Jejunal microcirculation was assessed by laser Doppler flowmetry (LDF). Intravascular volume was optimized using difference in pulse pressure (dPP) to keep dPP below 13%. Sixty minutes after p…

Cardiac outputMean arterial pressureColonHypovolemiaSus scrofaHemodynamicsBlood PressureHemorrhageBlood volumeHypovolemiaLaser-Doppler FlowmetryIntravascular volume statusmedicineAnimalsCardiac OutputPulmonary wedge pressureBlood Volumebusiness.industryMicrocirculationHemodynamicsBlood flowHeart ArrestOxygenDisease Models AnimalJejunumLiverAnesthesiaAcute DiseaseSurgerymedicine.symptombusinessJournal of Surgical Research
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Automatic algorithm for monitoring systolic pressure variation and difference in pulse pressure.

2009

BACKGROUND: Difference in pulse pressure (dPP) reliably predicts fluid responsiveness in patients. We have developed a respiratory variation (RV) monitoring device (RV monitor), which continuously records both airway pressure and arterial blood pressure (ABP). We compared the RV monitor measurements with manual dPP measurements. METHODS: ABP and airway pressure (PAW) from 24 patients were recorded. Data were fed to the RV monitor to calculate dPP and systolic pressure variation in two different ways: (a) considering both ABP and PAW (RV algorithm) and (b) ABP only (RV(slim) algorithm). Additionally, ABP and PAW were recorded intraoperatively in 10-min intervals for later calculation of dPP …

AdultMaleFluid responsivenessBlood PressureAutomationMonitoring IntraoperativeAbdomenMedicineHumansIn patientPulseAgedObserver VariationBlood Volumebusiness.industryAirway ResistanceLimits of agreementReproducibility of ResultsMiddle AgedReference StandardsPulse pressureAnesthesiology and Pain MedicineBlood pressureData Interpretation StatisticalRespiratory MechanicsFemalebusinessAlgorithmAlgorithmsAnesthesia and analgesia
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