0000000000042913

AUTHOR

Ludwin Trampert

showing 3 related works from this author

PSA and PSA Kinetics Thresholds for the Presence of 68Ga-PSMA-11 PET/CT-Detectable Lesions in Patients with Biochemical Recurrent Prostate Cancer

2020

68Ga-PSMA-11 positron-emission tomography/computed tomography (PET/CT) is commonly used for restaging recurrent prostate cancer (PC) in European clinical practice. The goal of this study is to determine the optimum time for performing these PET/CT scans in a large cohort of patients by identifying the prostate-specific-antigen (PSA) and PSA kinetics thresholds for detecting and localizing recurrent PC. This retrospective analysis includes 581 patients with biochemical recurrence (BC) by definition. The performance of 68Ga-PSMA-11 PET/CT in relation to the PSA value at the scan time as well as PSA kinetics was assessed by the receiver-operating-characteristic-curve (ROC) generated by plottin…

Biochemical recurrenceCancer Researchmedicine.medical_treatment68Gallium-PSMA PET/CTurologic and male genital diseaseslcsh:RC254-282030218 nuclear medicine & medical imaging03 medical and health sciencesProstate cancer0302 clinical medicine<sup>68</sup>gallium-psma pet/ctprostate-specific-antigenPSA kinetics thresholdsbiochemical recurrenceMedicineoptimal cutoff levelPET-CTPsa kineticsbusiness.industryProstatectomylcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensprostate cancermedicine.diseaseRadiation therapyProstate-specific antigenOncology030220 oncology & carcinogenesisRecurrent prostate cancerbusinessNuclear medicineCancers
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The significance of FNAC in diagnosing differentiated thyroid cancer and the discrepancy between theory and practice - a multi-centre study.

2020

 After non-invasive diagnostic modalities high risk thyroid nodules are investigated with fine needle aspiration cytology in order to find the right surgical strategy for suspected malignancies. Despite the clear recommendation by the European and the American associations (ETA, ATA) its clinical value is doubted and its importance in clinical practice not fully clarified. A multicentric study of 119 patients with differentiated thyroid cancer operated on in 24 surgical departments was conducted. The aim was not only to evaluate the use of FNAC as a diagnostic tool, but also to investigate its diagnostic validity and compare it with that of other, non-invasive diagnostic methods. FNAC was u…

Thyroid nodulesAdultMalemedicine.medical_specialtyAdolescentmedicine.medical_treatmentBiopsy Fine-NeedleScintigraphyCohort StudiesDiagnosis DifferentialYoung AdultBiopsymedicineHumansRadiology Nuclear Medicine and imagingThyroid Neoplasmsskin and connective tissue diseasesThyroid cancerAgedRetrospective StudiesAged 80 and overmedicine.diagnostic_testbusiness.industryRetrospective cohort studyGeneral MedicineMiddle Agedmedicine.diseasebody regionsLymphadenectomyFemaleRadiologyUltrasonographybusinessCohort studyNuklearmedizin. Nuclear medicine
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Diagnostic Performance of 68Ga-PSMA-11 Positron-emission-tomography/Computed-tomography in a Large Cohort of Patients with Biochemical Recurrence of …

2020

Gallium-68 (Ga) prostate-specific-membrane-antigen positron-emission-tomography/computed-tomography is a highly promising method for imaging primary and recurrent prostate cancer. These dual-modality imaging technologies enable whole-body functional and anatomical evaluation in a single session. This study investigated the performance of Ga-prostate-specific-membrane-antigen-11 positron-emission-tomography/computed-tomography for detecting prostate carcinoma in patients with rising prostate-specific-antigen after primary therapy. Six hundred sixty (660) patients with biochemical recurrence referred for positron-emission-tomography/computed-tomography with Ga-prostate-specific-membrane-antig…

Biochemical recurrenceMalemedicine.medical_specialtyEpidemiologyHealth Toxicology and MutagenesisGallium RadioisotopesRisk Assessment68Ga-PSMA-11Cohort StudiesProstate cancerPositron Emission Tomography Computed TomographymedicineHumansRadiology Nuclear Medicine and imagingRadiation treatment planningPathologicalEdetic AcidGallium IsotopesPositron Emission Tomography-Computed TomographyNeoplasm StagingRetrospective Studiesbusiness.industryProstatic NeoplasmsProstate carcinomamedicine.diseaseLarge cohortTreatment OutcomeGene Expression RegulationLymphatic MetastasisRadiologyNeoplasm Recurrence LocalbusinessOligopeptidesHealth physics
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