0000000000043218
AUTHOR
Radu Chicea
Biochemical and Immunological implications of Lutein and Zeaxanthin
Throughout history, nature has been acknowledged for being a primordial source of various bioactive molecules in which human macular carotenoids are gaining significant attention. Among 750 natural carotenoids, lutein, zeaxanthin and their oxidative metabolites are selectively accumulated in the macular region of living beings. Due to their vast applications in food, feed, pharmaceutical and nutraceuticals industries, the global market of lutein and zeaxanthin is continuously expanding but chemical synthesis, extraction and purification of these compounds from their natural repertoire e.g., plants, is somewhat costly and technically challenging. In this regard microbial as well as microalga…
Prenatal Diagnosis of Bovine Aortic Arch Anatomic Variant
Fetal aortic arch development is an early and complex process that depends on many genetic and environmental factors. The final aortic arch varies greatly; it may take the form of a normal arch, anatomic variant (AAAV) with a common origin to that of the innominate artery and left common carotid artery (formerly known as “bovine aortic arch” (with an incidence of up to 27%)) or one of multiple pathological conditions. The present study aimed to establish the feasibility and impact of prenatal anatomic arch variants’ diagnosis. A retrospective study of 271 fetal second- and third-trimester anomaly scans was performed in our tertiary center. Examinations that evaluated the s…
Cucumis sativus l. Seeds ameliorate muscular spasm-induced gastrointestinal and respiratory disorders by simultaneously inhibiting calcium mediated signaling pathway
Cucumis sativus L. is globally cultivated as an edible vegetable. Besides its nutritional benefits, it is used in traditional medicines against various ailments. The current study was designed to elucidate the multi-target mechanisms of a C. sativus seeds extract against asthma and diarrhea using network pharmacology along with a molecular docking approach. Furthermore, in-vitro and in-vivo experiments were conducted to verify the mechanistic insight of in silico studies. LC-ESI-MS/MS was performed to identify the bioactive compounds in the extract; later, some compounds were quantified by HPLC. C. sativus seed. EtOH has kaempferol in higher concentration 783.02 µg/g, followed by quercetin …
Effect of patella resurfacing on functional outcome and revision rate in primary total knee arthroplasty (Review).
Anterior knee pain, as well as patellofemoral disorders, after total knee arthroplasty are important reasons for revision in total knee arthroplasty. Current prosthesis designs include patellar components for patella replacement, and together with improved rational design of the prosthesis and advancement in knee alignment these appear to reduce the incidence of anterior knee pain following total knee replacement, even if the etiology of anterior knee pain remains unclear. However, new complications related to patella resurfacing emerge with this approach. At present, there are three strategies involving patella replacement in total knee arthroplasty: There are surgeons who always replace t…
Hysteroscopy for Uterine Cavity Assessment in Infertility
Abstract Hysteroscopy is a surgical procedure that allows a direct view of the uterine cavity and the tubular ostium. This procedure can be performed for both diagnostic and curative purposes. Hysteroscopy have several indications including the evaluation of abnormal uterine bleeding, infertility or intrauterine tumours identified by ultrasound. The purpose of this paper is to evaluate the correlation between the diagnosis at admission and the intraoperative aspect of the uterine cavity following the hysteroscopic evaluation. We evaluated the patients admitted to the Obstetrics and Gynaecology Clinic of the Sibiu County Emergency Clinical Hospital during 1.01.2019-07.06.2019 who had the fol…