CysLT1 receptor activation-induced adhesion of human eosinophils to bronchial epithelial cells: signal transduction and pharmacological modulation

Cigarette smoke upregulates TLR4 expression and enhances TLR4 mediated responses

Cigaretta smoke up-regulates toll like receptor 4 (TLR4) expression and enhances TLR4 mediated responses

Altered expression of TLR4 and beta 2 defensin in chronic obstructive pulmonary disease

Cigarette smoke up-regulates toll like receptor 4 (TLR4) expression and enhances TLR4 mediated responses

DOES LEPTIN PLAY A CYTOKINE ROLE WITHIN THE AIRWAYS OF COPD PATIENTS?

Functional role of PAR-1 receptors in the epithelial cells of smokers with and without COPD: involvement of intracellular signal pathways.

In vivo and in vitro effects of variants Parj2 in asthmatic children

Role of PGE2 in the invasiveness, growth and protection of cancer cells in malignant pleuritis

Abstract The recurrence of pleural effusions is a common event in a variety of neoplastic diseases. The objective of this study was to identify the mechanisms promoting the homing and growth of cancer cells within the pleural space. A cancer cell line recovered from malignant pleural fluids (lung adenocarcinoma cell line) that constitutively expresses cyclooxygenase 2 (COX-2) and all types of prostaglandin receptors was studied. It was first demonstrated using a matrigel system, that malignant pleural fluids increase the invasiveness of adenocarcinoma cells more than congestive heart failure (CHF) pleural fluids. Moreover, exposure to exudative malignant, but not to CHF pleural fluids, incr…

Functional role of PAR-1 receptors in the epithelial cells of smokers with and without COPD: involvement of intracellular pathway