0000000000052989

AUTHOR

Eva Balsa-canto

0000-0002-1978-2626

showing 4 related works from this author

A multiphase multiobjective dynamic genome-scale model shows different redox balancing among yeast species of the saccharomyces genus in fermentation

2021

Yeasts constitute over 1,500 species with great potential for biotechnology. Still, the yeast Saccharomyces cerevisiae dominates industrial applications, and many alternative physiological capabilities of lesser-known yeasts are not being fully exploited. While comparative genomics receives substantial attention, little is known about yeasts’ metabolic specificity in batch cultures. Here, we propose a multiphase multiobjective dynamic genome-scale model of yeast batch cultures that describes the uptake of carbon and nitrogen sources and the production of primary and secondary metabolites. The model integrates a specific metabolic reconstruction, based on the consensus Yeast8, and a kinetic …

Cryotolerant speciesPhysiologySaccharomyces cerevisiaeBatch fermentationsSaccharomyces speciesBiochemistryRedoxSaccharomycesMicrobiologyRedox balance03 medical and health sciencesSaccharomycesDynamic genome-scale modelsGeneticsMolecular BiologyEcology Evolution Behavior and Systematics030304 developmental biologyComparative genomics0303 health sciencesbiologyKinetic model030306 microbiologyChemistryKinetic modelbiology.organism_classificationYeastQR1-502YeastComputer Science ApplicationsFlux balance analysisMetabolismModeling and SimulationFermentationBiochemical engineeringBatch cultures
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A multi-phase multi-objective dynamic genome-scale model shows different redox balancing among yeast species in fermentation

2021

ABSTRACTYeasts constitute over 1500 species with great potential for biotechnology. Still, the yeastSaccharomyces cerevisiaedominates industrial applications and many alternative physiological capabilities of lesser-known yeasts are not being fully exploited. While comparative genomics receives substantial attention, little is known about yeasts’ metabolic specificity in batch cultures. Here we propose a multi-phase multi-objective dynamic genome-scale model of yeast batch cultures that describes the uptake of carbon and nitrogen sources and the production of primary and secondary metabolites. The model integrates a specific metabolic reconstruction, based on the consensus Yeast8, and a kin…

Comparative genomicsbiologyChemistrySaccharomyces cerevisiaeGenome scaleFermentationBiochemical engineeringbiology.organism_classificationSaccharomycesRedoxYeastFlux balance analysis
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Reverse-engineering post-transcriptional regulation of gap genes in Drosophila melanogaster

2013

16 páginas, 6 figuras, 1 tabla

Systems biologyContext (language use)Computational biology03 medical and health sciencesCellular and Molecular Neuroscience0302 clinical medicineKrüppelGeneticsAnimalsDrosophila ProteinsRNA MessengerMolecular BiologyPost-transcriptional regulationlcsh:QH301-705.5Ecology Evolution Behavior and SystematicsGap gene030304 developmental biologyGenetics0303 health sciencesEcologybiologyModels GeneticProtein StabilitySystems BiologyGene Expression Regulation Developmentalbiology.organism_classificationRepressor ProteinsDrosophila melanogasterComputational Theory and Mathematicslcsh:Biology (General)Modeling and SimulationIdentifiabilityDrosophila melanogasterGenetic Engineering030217 neurology & neurosurgeryDrosophila ProteinResearch Article
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A multi-phase multi-objective genome-scale model shows diverse redox balance strategies in yeasts

2021

Yeasts constitute over 1500 species with great potential for biotechnology. Still, the yeastSaccharomyces cerevisiaedominates industrial applications and many alternative physiological capabilities of lesser-known yeasts are not being fully exploited. While comparative genomics receives substantial attention, little is known about yeasts’ metabolic specificity in batch cultures. Here we propose a multi-phase multi-objective dynamic genome-scale model of yeast batch cultures that describes the uptake of carbon and nitrogen sources and the production of primary and secondary metabolites. The model integrates a specific metabolic reconstruction, based on the consensus Yeast8, and a kinetic mod…

Comparative genomicsFermentation in winemakingbiologyMulti phaseSaccharomyces cerevisiaeGenome scaleBiochemical engineeringbiology.organism_classificationRedoxYeastFlux balance analysis
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