0000000000054037
AUTHOR
Jérémy Paris
Phthalocyanine–titanate nanotubes: a promising nanocarrier detectable by optical imaging in the so-called imaging window
International audience; TiONts-phthalocyanine nanohybrids combining an efficient optical probe and a promising nanovector have been developed in a step-by-step approach and were thoroughly characterized. Each 150 nm long TiONts-Pc bear ca. 450 Pc. Three nanohybrids were prepared including three different linkers in quest for the best stability.
Iron oxides nanoparticles and titanate nanotubes dedicated to multimodal imaging and anticancer therapy
The new implementations of nanoparticles in the medical field are one of the essential factors of the medical progress expected at the beginning of this XXIst century. Thus, the domain of the medical imaging is also affected by this technological evolution. This work consisted in developing theranostic probes with iron oxides nanoparticles (SPIO) and titanate nanotubes (TiONts) for multimodal imaging (magnetic/nuclear or magnetic/optical) and also possessing a therapeutic effect (hyperthermia/PDT or radiosensitization/PDT).The titanate nanotubes of this study have an average length of about 150 nm and were obtained by Kasuga's hydrothermal synthesis. These nanotubes present an outside diame…
Magneto-optical nanomaterials: a SPIO–phthalocyanine scaffold built step-by-step towards bimodal imaging
A SPIO-phthalocyanine nanohybrid is developed as a bimodal contrast agent for Optical and Magnetic Resonance Imaging. The organic coating was covalently attached onto SPIO in a step-by-step approach. Each coated-SPIO was thoroughly characterized. The hydrodynamic size of the SPIO-Pc is ca. 60 nm with a coverage of ca. 690 Pc/SPIO.
One step continuous hydrothermal synthesis of very fine stabilized superparamagnetic nanoparticles of magnetite
International audience; Stable suspensions of citrated SPIO nanoparticles were synthesised in one step using a hydrothermal continuous process. Citrates control the crystallite size and the oxidation degree of metallic ions despite the very short reaction time (4 s). Magnetite particles, Fe2.94O4, with an average size of 4 nm and good monodispersity were obtained.