0000000000061645

AUTHOR

J. Castillo

showing 7 related works from this author

PO-182 The upregulation of EPDR1 is related to tumour invasiveness in a cohort of localised colorectal cancer patients

2018

Introduction Colorectal cancer (CRC) represents a relevant public health problem. Despite new therapeutic advances, prognosis of patients diagnosed with advanced disease is still poor. The identification of new markers involved in the mechanisms of invasiveness represents a priority in order to better understand cancer development and generate new therapeutic targets. We describe here the possible role of EPDR1, a gene not yet well characterised, which encodes a protein related to ependymins, a family of piscine transmembrane proteins involved in cell adhesion. To evaluate the role of EPDR1, a translational investigation was planned to explore the consequences of the upregulation of EPDR1 i…

OncologyCancer Researchmedicine.medical_specialtyGene knockdownNecrosisCell growthColorectal cancerbusiness.industrymedicine.diseaseOncologyDownregulation and upregulationInternal medicineCohortmedicineGene silencingmedicine.symptombusinessGrading (tumors)ESMO Open
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464P Exome sequencing of ctDNA portrays the mutational landscape of patients with relapsing colon cancer and indicates new actionable targets

2021

Oncologybusiness.industryColorectal cancerMedicineHematologyComputational biologybusinessmedicine.diseaseExome sequencingAnnals of Oncology
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NRF2 activation via PI3K/AKT/mTOR/RPS6 causes resistance to anti-HER2 agents among HER2 amplified gastric cancer

2018

0301 basic medicinebusiness.industryCancerHematologymedicine.diseaseNrf2 activation03 medical and health sciences030104 developmental biology0302 clinical medicineOncologyCancer researchMedicineAnti her2businessProtein kinase B030217 neurology & neurosurgeryPI3K/AKT/mTOR pathwayAnnals of Oncology
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UVER and UV index at high altitude in Northwestern Argentina

2016

Measurements of ultraviolet erythemal radiation (UVER) made during two years at three sites located at altitudes over 1000 m a.s.l. in Northwestern Argentina (Salta, San Carlos, and El Rosal) have been used to estimate and analyze the UV Index (UVI) and the cumulative doses at these locations. For the UVER irradiance, data of January (maximum values) and June (minimum values) have been analyzed as representative of the year for all locations. The UVI reaches extreme (> 11) values in > 20% of the analyzed days in Salta (1190 m a.s.l.), while these are reached in San Carlos (1611 m a.s.l.) and El Rosal (3355 m a.s.l.) in > 40% of the analyzed days. Finally, the cumulative doses over an averag…

0301 basic medicine030103 biophysicsVeterinary medicineMeteorologyUltraviolet erythemal radiation (UVER)Ultraviolet RaysBiophysicsIrradianceArgentinaRadiation DosageCumulative dosesCiencias de la Tierra y relacionadas con el Medio Ambiente03 medical and health sciencesRadiation MonitoringHigh altitudeRadiology Nuclear Medicine and imagingSouthern HemisphereRadiationRadiological and Ultrasound TechnologyAltitudeEffects of high altitude on humansUltraviolet index (UVI)Southern hemisphereEnvironmental scienceMeteorología y Ciencias AtmosféricasCIENCIAS NATURALES Y EXACTAS
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Gene expression changes responsible for lapatinib acquired resistance in HER2 positive gastric cancer cell lines: a microarray analysis

2017

Acquired resistanceOncologyCell culturebusiness.industryMicroarray analysis techniquesGene expressionCancer researchMedicineHematologybusinessLapatinibGastric cancer cellmedicine.drugAnnals of Oncology
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The miniJPAS survey: a preview of the Universe in 56 colours

2021

Full list of authors: Bonoli, S.; Marín-Franch, A.; Varela, J.; Vázquez Ramió, H.; Abramo, L. R.; Cenarro, A. J.; Dupke, R. A.; Vílchez, J. M.; Cristóbal-Hornillos, D.; González Delgado, R. M.; Hernández-Monteagudo, C.; López-Sanjuan, C.; Muniesa, D. J.; Civera, T.; Ederoclite, A.; Hernán-Caballero, A.; Marra, V.; Baqui, P. O.; Cortesi, A.; Cypriano, E. S.; Daflon, S.; de Amorim, A. L.; Díaz-García, L. A.; Diego, J. M.; Martínez-Solaeche, G.; Pérez, E.; Placco, V. M.; Prada, F.; Queiroz, C.; Alcaniz, J.; Alvarez-Candal, A.; Cepa, J.; Maroto, A. L.; Roig, F.; Siffert, B. B.; Taylor, K.; Benitez, N.; Moles, M.; Sodré, L.; Carneiro, S.; Mendes de Oliveira, C.; Abdalla, E.; Angulo, R. E.; Apari…

Cosmology and Nongalactic Astrophysics (astro-ph.CO)media_common.quotation_subjectFOS: Physical sciencesAstrophysicsastronomical databases: miscellaneousSurveyslaw.inventionPhotometry (optics)Telescopetechniques: photometricExtended Groth StripsurveysObservatorylaw[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]observations [Cosmology]Instrumentation and Methods for Astrophysics (astro-ph.IM)stars: generalmedia_commonPhysicsgeneral [Stars]photometric [Techniques]Astronomy and AstrophysicsQuasargeneral [Galaxies]115 Astronomy Space sciencegalaxies: generalAstrophysics - Astrophysics of GalaxiesGalaxyRedshiftSpace and Planetary ScienceSkyAstrophysics of Galaxies (astro-ph.GA)cosmology: observationsmiscellaneous [Astronomical databases][PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]Astrophysics - Instrumentation and Methods for AstrophysicsAstrophysics - Cosmology and Nongalactic Astrophysics
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1432P Characterizing diversity in the immune profile by a transcriptomic customized gene signature to potentially personalize treatment in advanced g…

2021

TranscriptomeImmune systemOncologybusiness.industrymedia_common.quotation_subjectMedicineHematologyComputational biologyAdvanced gastric cancerGene signaturebusinessDiversity (politics)media_commonAnnals of Oncology
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