0000000000065815

AUTHOR

Serena Donadio

showing 3 related works from this author

Impact of COVID-19 Pandemic on Children and Adolescents with Neuropsychiatric Disorders: Emotional/Behavioral Symptoms and Parental Stress.

2022

The objective of our study was to evaluate the impact of the COVID-19 pandemic on the emotional and behavioral symptoms in minors with neuropsychiatric disorders and on parental stress through a standardized neuropsychological assessment, comparing the data collected before the pandemic with those collected during the lock-down. Another goal of our study was to analyze the relationship between parental stress and behavioral/emotional symptoms in children. Our study was conducted on 383 families of patients who had already been referred at the Child Neuropsychiatry Unit of the University Hospital of Salerno for different neuropsychiatric conditions. All the parents completed two neuropsychol…

COVID-19; neuropsychiatric disorders; children; adolescents; emotional behavioral symptoms; parental stressProblem BehaviorPandemicAdolescentParentingHealth Toxicology and MutagenesisPublic Health Environmental and Occupational HealthCOVID-19parental stressNeuropsychiatric disorderParental streCommunicable Disease ControlHumansChildChildrenPandemicsEmotional behavioral symptomHumanInternational journal of environmental research and public health
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Exome sequencing in a child with neurodevelopmental disorder and epilepsy: Variant analysis of the AHNAK2 gene

2022

Background The AHNAK2 gene encodes a large nucleoprotein expressed in several tissues, including brain, squamous epithelia, smooth muscle, and neuropil. Its role in calcium signaling has been suggested and to date, clear evidence about its involvement in the pathogenesis of clinical disorders is still lacking. Methods Here, we report a female 24-year-old patient diagnosed with a cardio-facio-cutaneous-like phenotype (CFC-like), characterized by epilepsy, psychomotor development delay, atopic dermatitis, congenital heart disease, hypotonia, and facial dysmorphism, who is compound heterozygote for two missense mutations in the AHNAK2 gene detected by exome sequencing. Results This patient had…

Heart Defects CongenitalAHNAK2 borderline intellectual functioning epilepsy facio-cardio-cutaneous-like phenotype NGS exomefacio-cardio-cutaneous-like phenotypeFaciesNGS exomeSettore MED/39 - Neuropsichiatria InfantileFailure to ThriveNucleoproteinsEctodermal DysplasiaNeurodevelopmental DisordersAHNAK2borderline intellectual functioningGeneticsHumansepilepsyExomeFemaleMolecular BiologyGenetics (clinical)Molecular Genetics & Genomic Medicine
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Sensory-Adapted Dental Environment for the Treatment of Patients with Autism Spectrum Disorder.

2022

Purpose: The importance of dental care and oral hygiene is often underestimated in people with autism spectrum disorder (ASD). Comorbidity with dental anxiety is greater in ASD subjects who also show unusual reactions to sensory stimuli. The aim of our study was to assess the efficacy for a sensory-adapted environment and targeted methods in reducing anxiety and positively influencing cooperation in children with ASD during a dental examination or specific treatments. Material and methods: The sample consisted of 50 Italian children with a diagnosis of ASD (36 males and 14 females; aged 9–10 years) presenting with mild intellectual disability (ID) and verbal language skills. The subjects en…

sensory processing; dental anxiety; autismstomatognathic diseasesstomatognathic systemAutismPediatrics Perinatology and Child Healthmental disordersSensory processingbehavioral disciplines and activitiesDental anxietySettore MED/39 - Neuropsichiatria InfantileChildren (Basel, Switzerland)
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