0000000000066660

AUTHOR

Domenico A. Restivo

showing 3 related works from this author

Anodal transcranial direct current stimulation and intermittent theta-burst stimulation improve deglutition and swallowing reproducibility in elderly…

2019

Background: Dysphagia in the elderly, known as presbydysphagia, has become a relevant public health problem in several countries. Swallowing disorders may be a consequence of different neurological disorders (secondary presbydysphagia) or the expression of the aging process itself (primary presbydysphagia). We aimed to test the therapeutic potential of two different non-invasive brain stimulation (NIBS) techniques in subjects with primary or secondary presbydysphagia. Methods: A blinded randomized controlled trial with crossover design was carried out in 42 patients, randomly assigned to anodal transcranial direct current stimulation (tDCS) or intermittent theta-burst stimulation (TBS) grou…

MalePhysiologymedicine.medical_treatmentbrain stimulationStimulationTranscranial Direct Current StimulationtDCSlaw.invention030507 speech-language pathology & audiology03 medical and health sciences0302 clinical medicineSwallowingRandomized controlled trialDouble-Blind MethodlawmedicineHumansTBSProspective StudiesAgedCross-Over StudiesTranscranial direct-current stimulationEndocrine and Autonomic Systemsbusiness.industrySwallowing DisordersGastroenterologyMotor CortexCrossover studyDysphagiaDeglutitionTreatment OutcomepresbydysphagiaBrain stimulationAnesthesiaTMSFemalemedicine.symptom0305 other medical sciencebusinessDeglutition Disorders030217 neurology & neurosurgery
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Botulinum Toxin Is Effective in the Management of Neurogenic Dysphagia. Clinical-Electrophysiological Findings and Tips on Safety in Different Neurol…

2017

Background and Aims: Neurogenic dysphagia linked to failed relaxation of the upper esophageal sphincter (UES) can be treated by injecting botulinum toxin (BTX) into the cricopharyngeal (CP) muscle. We compared the effects of this treatment in different neurological disorders with dysphagia, to evaluate its efficacy over time including the response to a second injection. Materials and Methods: Sixty-seven patients with neurogenic dysphagia associated with incomplete or absent opening of the UES (24 with brainstem or hemispheric stroke, 21 with parkinsonian syndromes, 12 with multiple sclerosis, and 10 with spastic-dystonic syndromes secondary to post-traumatic encephalopathy) were treated wi…

Side effectEncephalopathyupper esophageal sphincter dysmotilityneurogenic dysphagia03 medical and health sciences0302 clinical medicineSwallowingmedicineIngestionPharmacology (medical)botulinum toxinOriginal ResearchPharmacologybusiness.industryelectrophysiological study of swallowingMultiple sclerosiscricopharyngeal musclemedicine.diseaseDysphagiaBotulinum toxinPneumoniaAnesthesia030211 gastroenterology & hepatologymedicine.symptombusiness030217 neurology & neurosurgerymedicine.drugFrontiers in Pharmacology
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Electrophysiological patterns of oropharyngeal swallowing in multiple sclerosis.

2012

Abstract Objective We performed an electrophysiological study of swallowing (EPSS) in multiple sclerosis (MS) to describe oropharyngeal swallowing abnormalities and to analyze their correlations with dysphagia and with overall neurological impairment. Methods Neurological examinations were quantified using the Kurtzke Functional Systems and the Expanded Disability Status Scale (EDSS). Dysphagia was evaluated using the Dysphagia in Multiple Sclerosis (DYMUS) questionnaire, while fiberoptic endoscopic evaluation of swallowing (FEES) was used to establish the degree of aspiration and penetration, graded using the penetration–aspiration scale (PAS). The EPSS measured the duration of suprahyoid/…

AdultMalemedicine.medical_specialtyMultiple SclerosisOropharynxElectromyographyBladder Sphincter DysfunctionDysphagia swallowing electromiography multiple sclerosisSwallowingPhysiology (medical)otorhinolaryngologic diseasesmedicineHumansAgedExpanded Disability Status Scalemedicine.diagnostic_testbusiness.industryElectromyographyMultiple sclerosisMiddle Agedmedicine.diseaseDysphagiaSensory SystemsPathophysiologySurgeryDeglutitionNeurologyAnesthesiaFemaleNeurology (clinical)medicine.symptomAbnormalitybusinessDeglutition DisordersClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
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