0000000000067408

AUTHOR

Līga Balode

showing 4 related works from this author

Lipoxygenase-derived arachidonic acid metabolites in chronic obstructive pulmonary disease

2011

Background and Objective. Chronic obstructive pulmonary disease (COPD) is characterized by a persistence of inflammation in large and small airways. We hypothesized that this could be caused by the inability of an inflammatory process to resolve. In the resolution of inflammation, a switching of arachidonic acid metabolism from the production of proinflammatory leukotriene B4 (LtB4) to the synthesis of anti-inflammatory lipoxins plays an important role. The aim of our study was to determine the content of lipoxin A4 (LXA4) and LtB4 in induced sputum of patients with exacerbated COPD and to compare it to healthy controls, as well as to analyze the relationship between proinflammatory and ant…

MaleSputum CytologyExacerbationLeukotriene B4InflammationLeukotriene B4Proinflammatory cytokinePulmonary Disease Chronic Obstructivechemistry.chemical_compoundHumansMedicineCOPDbusiness.industrySputumGeneral MedicineMiddle Agedmedicine.diseaserespiratory tract diseasesLipoxinschemistrychronic obstructive pulmonary disease; exacerbation; lipoxin A<sub>4</sub>; leukotriene B<sub>4</sub>ImmunologyAbsolute neutrophil countSputumFemalelipids (amino acids peptides and proteins)medicine.symptombusiness
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Relation of Endothelial Dysfunction and Adipokines Levels to Insulin Resistance in Metabolic Syndrome Patients

2009

Relation of Endothelial Dysfunction and Adipokines Levels to Insulin Resistance in Metabolic Syndrome Patients Obese metabolic syndrome (MS) patients were categorised into three groups: 44 with type 2 diabetes mellitus (T2DM)(D); 20 with T2DM and coronary artery disease (CAD) (DC), and 26 with MS alone (M). Eighteen healthy subjects were selected as controls (C). Insulin resistance (IR) was assessed by HOMA-IR. Adiponectin, tumour necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), monocyte chemoattractant protein-1 (MCP-1), and interleukin-8 (IL-8) concentrations were measured by xMAP technology. Endothelin-1 (ET-1) was determined by ELISA. We used laser Doppler imaging for evaluating cut…

medicine.medical_specialtyMultidisciplinaryAdiponectinGeneral interestadiponectininflammatory cytokinesScienceQAdipokinemedicine.diseasemetabolic syndromeendothelial dysfunctionProinflammatory cytokineInsulin resistanceEndocrinologyInternal medicineinsulin resistancemedicineEndothelial dysfunctionMetabolic syndromeProceedings of the Latvian Academy of Sciences. Section B, Natural Sciences
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587 VASOMOTOR DYSFUNCTION AND ALTERATIONS OF CIRCULATING CYTOKINES IN DIABETIC POLYNEUROPATHY PATIENTS WITH AND WITHOUT MECHANICAL ALLODYNIA

2009

medicine.medical_specialtyAnesthesiology and Pain MedicineDiabetic polyneuropathybusiness.industryInternal medicineCardiologymedicineVasomotor dysfunctionbusinessMechanical AllodyniaEuropean Journal of Pain
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Leikotriēna B4 un lipoksīna A4 loma plaušaudu iekaisuma hronizācijas patoģenēzē

2013

Elektroniskā versija nesatur pielikumus

PatoloģijaLungs (Diseases Obstructive)Medicīna un farmācijaVeselības aprūpeMedicīnaPlaušas (Slimības)
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