0000000000067521

AUTHOR

Leila Rezig

0000-0002-6243-5742

showing 2 related works from this author

Prevention of 7-ketocholesterol-induced side effects by natural compounds

2018

Cholesterol oxidation products, also named oxysterols, can be formed either by cholesterol auto-oxidation, enzymatically or both. Among these oxysterols, 7-ketocholesterol (7KC) is mainly formed during radical attacks that take place on the carbon 7 of cholesterol. As increased levels of 7KC have been found in the tissues, plasma and/or cerebrospinal fluid of patients with major diseases, especially age-related diseases (cardiovascular diseases, eye diseases, neurodegenerative diseases), some cancers, and chronic inflammatory diseases, it is suspected that 7KC, could contribute to their development. Since 7KC, provided by the diet or endogenously formed, is not or little efficiently metabol…

Programmed cell deathOxysterol030309 nutrition & dieteticsTocopherolsInflammationPharmacologymedicine.disease_causeAntioxidantsIndustrial and Manufacturing Engineering03 medical and health scienceschemistry.chemical_compound0404 agricultural biotechnologymedicineHumansNoncommunicable DiseasesKetocholesterolsInflammation0303 health sciencesCholesterolFatty AcidsPolyphenols04 agricultural and veterinary sciencesGeneral Medicine040401 food scienceCytoprotectionOxidative StressMetabolic pathwaychemistryHepatic stellate cellmedicine.symptomOxidation-ReductionOxidative stressFood ScienceCritical Reviews in Food Science and Nutrition
researchProduct

Tunisian Milk Thistle: An Investigation of the Chemical Composition and the Characterization of Its Cold-Pressed Seed Oils

2017

In this study, milk thistle seeds growing in different areas in Tunisia were cold pressed and the extracted oils were examined for their chemical and antioxidant properties. The major fatty acids were linoleic acid (C18:2) (57.0%, 60.0%, and 60.3% for the milk thistle seed oils native to Bizerte, Zaghouan and Sousse, respectively) and oleic acid (C18:1) (15.5%, 21.5%, and 22.4% for the milk thistle seed oils originating from Bizerte, Zaghouan and Sousse, respectively). High performance liquid chromatography (HPLC) analysis showed the richness of the milk thistle seed oils (MTSO) in α-tocopherol. The highest content was recorded for that of the region of Zaghouan (286.22 mg/kg). The total ph…

0301 basic medicineTunisiaAntioxidantmedicine.medical_treatmentLinoleic acidalpha-Tocopherolfatty acidsHigh-performance liquid chromatographyAntioxidantsArticleCatalysislcsh:ChemistryInorganic Chemistry03 medical and health scienceschemistry.chemical_compound0404 agricultural biotechnologyHydroxybenzoatesmedicineVanillic acidMilk ThistlePlant OilsFood scienceGallic acidPhysical and Theoretical Chemistrylcsh:QH301-705.5milk thistle seed oil; fatty acids; phenolic acids; tocopherols; differential scanning calorimetryMolecular BiologyChemical compositionSpectroscopy030109 nutrition & dieteticsCalorimetry Differential ScanningMilk Thistlemilk thistle seed oilOrganic Chemistryfood and beverages04 agricultural and veterinary sciencesGeneral Medicine040401 food scienceComputer Science ApplicationsOleic acidlcsh:Biology (General)lcsh:QD1-999chemistrySeedsdifferential scanning calorimetryphenolic acidstocopherolsChromatography LiquidInternational Journal of Molecular Sciences
researchProduct