0000000000069746

AUTHOR

Alfred Ongaro

showing 2 related works from this author

Human nasoseptal chondrocytes maintain their differentiated phenotype on PLLA scaffolds produced by thermally induced phase separation and supplement…

2018

Damage of hyaline cartilage such as nasoseptal cartilage requires proper reconstruction, which remains challenging due to its low intrinsic repair capacity. Implantation of autologous chondrocytes in combination with a biomimetic biomaterial represents a promising strategy to support cartilage repair. Despite so far mostly tested for bone tissue engineering, bioactive glass (BG) could exert stimulatory effects on chondrogenesis. The aim of this work was to produce and characterize composite porous poly(L-lactide) (PLLA)/1393BG scaffolds via thermally induced phase separation (TIPS) technique and assess their effects on chondrogenesis of nasoseptal chondrocytes. The PLLA scaffolds without or…

Malecartilage tissue engineering02 engineering and technologyBiochemistrylaw.inventionExtracellular matrixX-Ray DiffractionlawOrthopedics and Sports MedicineGlycosaminoglycansExtracellular Matrix Proteins0303 health sciencesSettore ING-IND/24 - Principi Di Ingegneria ChimicaCalorimetry Differential ScanningTissue ScaffoldsChemistryHyaline cartilageTemperatureSettore ING-IND/34 - Bioingegneria IndustrialeCell DifferentiationMiddle AgedPhenotypemedicine.anatomical_structureBioactive glassFemaleAdultPolyesters0206 medical engineeringType II collagenNoseChondrocyteYoung Adult03 medical and health sciencesChondrocytesRheumatologymedicineHumanspoly(L)lactic acidCollagen Type IIMolecular BiologyAggrecan030304 developmental biologyCartilagenasoseptal chondrocyteCell BiologyChondrogenesis020601 biomedical engineeringBioactive glass 1393Gene Expression RegulationBiophysicschondrogenesiGlassCollagen Type X
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Human nasoseptal chondrocytes maintain their differentiated phenotype on PLLA scaffolds produced by thermally induced phase separation and supplement…

2018

Damage of hyaline cartilage such as nasoseptal cartilage requires proper reconstruction, which remains challenging due to its low intrinsic repair capacity. Implantation of autologous chondrocytes in combination with a biomimetic biomaterial represents a promising strategy to support cartilage repair. Despite so far mostly tested for bone tissue engineering, bioactive glass (BG) could exert stimulatory effects on chondrogenesis. The aim of this work was to produce and characterize composite porous poly(L-lactide) (PLLA)/1393BG scaffolds via thermally induced phase separation (TIPS) technique and assess their effects on chondrogenesis of nasoseptal chondrocytes. The PLLA scaffolds without or…

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