Amplitude, Latency, and Peak Velocity in Accommodation and Disaccommodation Dynamics
The aim of this work was to ascertain whether there are differences in amplitude, latency, and peak velocity of accommodation and disaccommodation responses when different analysis strategies are used to compute them, such as fitting different functions to the responses or for smoothing them prior to computing the parameters. Accommodation and disaccommodation responses from four subjects to pulse changes in demand were recorded by means of aberrometry. Three different strategies were followed to analyze such responses: fitting an exponential function to the experimental data; fitting a Boltzmann sigmoid function to the data; and smoothing the data. Amplitude, latency, and peak velocity of …
Validation of a spectral light scattering method to differentiate large from small particles in intraocular lenses
A psychophysical approach has been designed to measure straylight from intraocular lenses (IOLs) in vitro. This approach uses a clinical straylight meter (C-Quant) and an observer's eye as optical detector. Based on this, we introduced a method for study of straylight-wavelength dependency for IOLs. This dependency can be used to distinguish between 2 types of scattering particles (small and large) as defined by Mie theory. Validation was performed using a turbidity standard and scattering filters. Several IOLs were analyzed to identify potential scattering sources. Large particles were found to predominate in scattering from the studied lenses. This was confirmed by straylight-angular depe…
Visual simulation of different optical designs
La presbicia es la pérdida irreversible de la capacidad de acomodar del ojo humano asociada a la edad, que afecta al rendimiento visual para con objetos cercanos. La presente Tesis Doctoral tiene como objetivo evaluar los aspectos ópticos y visuales de diferentes diseños multifocales para el tratamiento de la presbicia que se encuentran en lentes de contacto e intraoculares. En primer lugar, se implementó una métrica que facilita la evaluación in vitro de las lentes intraoculares. La idea de esta métrica se basa en la función de transferencia de modulación axial de las lentes intraoculares, la cual puede obtenerse con un instrumento de laboratorio adecuado. La métrica evalúa el volumen bajo…
Objective assessment of the effect of pupil size upon the power distribution of multifocal contact lenses
AIM: To analytically assess the effect of pupil size upon the refractive power distributions of different designs of multifocal contact lenses. METHODS: Two multifocal contact lenses of center-near design and one multifocal contact lens of center-distance design were used in this study. Their power profiles were measured using the NIMO TR1504 device (LAMBDA-X, Belgium). Based on their power profiles, the power distribution was assessed as a function of pupil size. For the high addition lenses, the resulting refractive power as a function of viewing distance (far, intermediate, and near) and pupil size was also analyzed. RESULTS: The power distribution of the lenses was affected by pupil siz…
Optical quality of rotationally symmetrical contact lenses derived from their power profiles.
To present a methodology for evaluating the optical quality of rotationally symmetrical contact lenses (CLs) from a single power profile.Simulated rotationally symmetrical power profiles corresponding to different CLs designs (monofocal, two-zone center-near bifocal, and four-zone center-distance bifocal) were used to calculate the wavefront error profile by means of numerical integration. Then, each lens wavefront error profile was spun around the center to obtain the lens wavefront error surface. From the surface, monochromatic optical transfer functions (OTF), simulated images and the visual Strehl ratio based on the OTF (VSOTF) were obtained for different distances and pupil sizes (3 an…
Temporal multiplexing with adaptive optics for simultaneous vision.
We present and test a methodology for generating simultaneous vision with a deformable mirror that changed shape at 50 Hz between two vergences: 0 D (far vision) and −2.5 D (near vision). Different bifocal designs, including toric and combinations of spherical aberration, were simulated and assessed objectively. We found that typical corneal aberrations of a 60-year-old subject changes the shape of objective through-focus curves of a perfect bifocal lens. This methodology can be used to investigate subjective visual performance for different multifocal contact or intraocular lens designs.
Assessing the in vitro optical quality of presbyopic solutions based on the axial modulation transfer function.
Purpose To present a metric for assessing the in vitro optical quality of rotationally symmetrical optical elements based on volume calculation under the surface defined by the axial modulation transfer function (MTF). Setting University of Valencia, Valencia, Spain. Design Experimental study. Methods The metric volume under the axial MTF was used to assess the optical quality of 2 rotationally symmetrical multifocal intraocular lenses (IOLs) within various defocus intervals (0.50 diopter [D], 0.75 D, and 1.00 D) and at various spatial frequency intervals (7.5 cycles per degree [cpd], 15.0 cpd, and 30.0 cpd). Results The far focus of the bifocal IOL yielded higher volume values at all spati…
Tolerance to rotation of toric monofocal and bifocal intraocular lenses. A theoretical study
Abstract This manuscript aims to evaluate the tolerance to rotation of a toric monofocal and a toric bifocal intraocular lenses with different cylinder powers. Theoretical designs based on wavefront aberrations were created to simulate a toric monofocal and a toric bifocal intraocular lens. Cylinder power ranged from −1 D to −6 D, in steps of −1 D. Tolerance to rotation was estimated by the visual Strehl ratio based on the optical transfer function (VSOTF) metric. Tolerance to rotation for both monofocal and bifocal intraocular lenses decreased when the cylinder power increased. For the bifocal design studied, the tolerance to rotation was larger for the near focus than for the far, however…
Hydrogen isotopes reveal evidence of migration of Miniopterus schreibersii in Europe
Abstract Background The Schreiber’s bat, Miniopterus schreibersii, is adapted to long-distance flight, yet long distance movements have only been recorded sporadically using capture-mark-recapture. In this study, we used the hydrogen isotopic composition of 208 wing and 335 fur specimens from across the species' European range to test the hypothesis that the species migrates over long distances. Results After obtaining the hydrogen isotopic composition (δ2H) of each sample, we performed geographic assignment tests by comparing the δ2H of samples with the δ2H of sampling sites. We found that 95 bats out of 325 showed evidence of long-distance movement, based on the analysis of either fur or …
Additional file 1 of Hydrogen isotopes reveal evidence of migration of Miniopterus schreibersii in Europe
Additional file 1. Summary of sampling sites and result outputs.