0000000000076124

AUTHOR

Richard J. Brown

0000-0003-3961-2023

showing 2 related works from this author

Symptoms and the body: Taking the inferential leap

2017

The relationship between the conscious experience of physical symptoms and indicators of objective physiological dysfunction is highly variable and depends on characteristics of the person, the context and their interaction. This relationship often breaks down entirely in the case of "medically unexplained" or functional somatic symptoms, violating the basic assumption in medicine that physical symptoms have physiological causes. In this paper, we describe the prevailing theoretical approach to this problem and review the evidence pertaining to it. We then use the framework of predictive coding to propose a new and more comprehensive model of the body-symptom relationship that integrates ex…

Predictive codingConsciousnessCognitive Neurosciencemedia_common.quotation_subject: Neurosciences & comportement [H07] [Sciences sociales & comportementales psychologie]Medically unexplainedContext (language use)Bayesian030227 psychiatryDevelopmental psychologyInteroception03 medical and health sciencesBehavioral NeuroscienceVariable (computer science)0302 clinical medicineNeuropsychology and Physiological PsychologySymptom perceptionCurrent theoryHumans: Neurosciences & behavior [H07] [Social & behavioral sciences psychology]ConsciousnessPsychology030217 neurology & neurosurgeryCognitive psychologymedia_common
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Idiopathic Environmental Intolerance: A Comprehensive Model

2017

Idiopathic environmental intolerance refers to a group of poorly understood health conditions characterized by heterogeneous somatic symptoms that occur in response to environmental triggers, but for which no physiological causes can be found. We focus on three varieties, namely symptoms attributed to (a) chemical substances, (b) electromagnetic fields, and (c) infrasound and vibroacoustic sources. As no clear link with organ pathology or dysfunction has been established so far, we review critical evidence about alternative causal mechanisms as a platform for a novel unifying model of these conditions. There is consistent evidence that expectancy and nocebo mechanisms are critically involve…

Nocebobusiness.industryEnvironmental Intolerancemedicine.diseaseIdiopathic environmental intoleranceEnvironmental stressDevelopmental psychology03 medical and health sciencesClinical Psychology0302 clinical medicineMedicine030212 general & internal medicinebusiness030217 neurology & neurosurgeryMultiple chemical sensitivityClinical psychologyClinical Psychological Science
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