Author: Adrian F. Sagebiel

0000000000076151

AUTHOR

Adrian F. Sagebiel

showing 1 related works from this author

The Transcription Factor Promyelocytic Leukemia Zinc Finger Protein Is Associated With Expression of Liver‐Homing Receptors on Human Blood CD56bright…

2020

The transcription factor promyelocytic leukemia zinc finger protein (PLZF) is involved in the development of natural killer (NK) cells and innate lymphoid cells, including liver‐resident NK cells in mice. In human NK cells, the role of PLZF in liver residency is still unknown. Expression of PLZF in matched human peripheral blood‐ and liver‐derived NK cells and the association of PLZF expression with surface molecules and transcription factors relevant for tissue residency were investigated using multiparameter flow cytometry and assessing single‐cell messenger RNA (mRNA) levels. Intrahepatic cluster of differentiation (CD)56bright NK cells expressed significantly higher levels of PLZF than …

[SDV.IMM] Life Sciences [q-bio]/ImmunologyPopulationCellC-C chemokine receptor type 6Biology03 medical and health sciences0302 clinical medicinemedicinelcsh:RC799-869ReceptoreducationTranscription factor030304 developmental biology0303 health sciencesMessenger RNAeducation.field_of_studyHepatologyCluster of differentiationInnate lymphoid cellOriginal ArticlesSISTM3. Good healthmedicine.anatomical_structureCancer research[SDV.IMM]Life Sciences [q-bio]/ImmunologyOriginal Articlelcsh:Diseases of the digestive system. Gastroenterology030215 immunologyHepatology Communications

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PEPhysical Sciences and Engineering
- PE2Fundamental Constituents of Matter
  - PE2_1Theory of fundamental interactions
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  - PE2_7Nuclear and particle astrophysics
  - PE2_9 Electromagnetism
  - PE2_10Atomic, molecular physics
  - PE2_11Ultra-cold atoms and molecules
  - PE2_18Equilibrium and non-equilibrium statistical mechanics: steady states and dynamics
  - PE2_14Lasers, ultra-short lasers and laser physics
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  - PE2_16Non-linear physics
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  - PE2_13Quantum optics and quantum information
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- PE1Mathematics
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LSLife Sciences
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SHSocial Sciences and Humanities
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