0000000000076819

AUTHOR

P. Montemaggi

showing 5 related works from this author

Palliative splenic irradiation in primary and post PV/ET myelofibrosis: outcomes and toxicity of three radiation schedules

2009

Splenectomy and splenic irradiation (SI) are the sole treatment modalities to control drug resistant splenomegaly in patients with myelofibrosis (MF). SI has been used in poor surgical candidates but optimal total dose and fractionation are unclear. We retrospectively reviewed 14 MF patients with symptomatic splenomegaly. Patients received a median of 10 fractions in two weeks. Fraction size ranged from 0.2–1.4 Gy, and total dose varied from 2–10.8 Gy per RT course. Overall results indicate that 81.8% of radiation courses achieved a significant spleen reduction. Splenic pain relief and gastrointestinal symptoms reduction were obtained in 94% and 91% of courses, respectively. Severe cytopeni…

medicine.medical_specialtypalliationmedicine.medical_treatmentSplenectomyMyelofibrosisSpleenSubgroup analysisGastroenterologyArticleInternal medicineMedicinemyelofibrosis; splenomegaly; palliation; radiotherapy; low-dose irradiationMyelofibrosisAdverse effectradiotherapylow dose irradiationsplenomegalylcsh:RC633-647.5business.industrylow-dose irradiation.lcsh:Diseases of the blood and blood-forming organsHematologymedicine.diseaseSurgeryRadiation therapymedicine.anatomical_structureTolerabilityToxicitybusinessHematology Reports
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Temozolomide (TMZ) in radio-chemotherapy combined schedule for treatment of newly-diagnosed high-grade gliomas (HGG)

2005

1578 Background: Temozolomide (TMZ) is an oral alkylating agent known to cross the blood-brain barrier with efficacy against HGG and a favourable safety profile compared to conventional chemotherap...

OncologyCancer Researchmedicine.medical_specialtyScheduleTemozolomideSettore MED/06 - Oncologia Medicabusiness.industryNewly diagnosedSurgerySafety profileOncologyInternal medicinemedicinebusinessmedicine.drugRadio chemotherapyJournal of Clinical Oncology
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Splenic Irradiation (SI) in Myelofibrosis: Outcomes and Toxicity of Three Radiation Schedule

2008

OncologyCancer Researchmedicine.medical_specialtyScheduleRadiationbusiness.industrymedicine.diseaseSurgeryOncologyInternal medicineToxicitymedicineRadiology Nuclear Medicine and imagingSplenic irradiationbusinessMyelofibrosisInternational Journal of Radiation Oncology*Biology*Physics
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Three-dimensional conformal radiotherapy in localized carcinoma of prostate: preliminary reports of toxicity in dose-escalation treatment

2007

Purpose Many studies confirmed the evidence of a dose-response relationship in prostate cancer. Escalation of dose using conventional techniques is however limited by rectal tolerance. IMRT and 3D-CRT have been designed to allow dose escalation while not exceeding rectal tolerance. We evaluated the acute and early late tolerance to surrounding organs upon dose escalation from 70 to 78 Gy in 3D-CRT setting, in order to introduce the IMRT process as a routine practice in prostate cancer treatment. Materials and Methods We compared clinical data from 35 patients with localized adenocarcinoma of the prostate, who received 70 Gy within a traditional reconstructed three-dimensional treatment plan…

Oncologymedicine.medical_specialtyGenitourinary systembusiness.industrymedicine.medical_treatmentRectumGeneral Medicinemedicine.diseaseRadiation therapyProstate cancermedicine.anatomical_structureProstateInternal medicineToxicitymedicineAdenocarcinomaRadiologyRadiation treatment planningbusinessRivista Urologia
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Early stage nasal vestibule tumors: safety and efficacy of HDR brachyterapy in elderly patients

2009

nasal vestibule tumorbrachyterapy
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