0000000000077774

AUTHOR

Jesús Rico-sanz

showing 1 related works from this author

Mediterranean Diet Reduces the Adverse Effect of the TCF7L2-rs7903146 Polymorphism on Cardiovascular Risk Factors and Stroke Incidence

2013

OBJECTIVE Transcription factor 7-like 2 (TCF7L2) polymorphisms are strongly associated with type 2 diabetes, but controversially with plasma lipids and cardiovascular disease. Interactions of the Mediterranean diet (MedDiet) on these associations are unknown. We investigated whether the TCF7L2-rs7903146 (C>T) polymorphism associations with type 2 diabetes, glucose, lipids, and cardiovascular disease incidence were modulated by MedDiet. RESEARCH DESIGN AND METHODS A randomized trial (two MedDiet intervention groups and a control group) with 7,018 participants in the PREvención con DIetaMEDiterránea study was undertaken and major cardiovascular events assessed. Data were analyzed at b…

Malemedicine.medical_specialtyCardiovascular and Metabolic RiskMediterranean dietEndocrinology Diabetes and MetabolismPopulationType 2 diabetesDiet MediterraneanGastroenterologylaw.inventionRandomized controlled triallawRisk FactorsDiabetes mellitusInternal medicineInternal MedicinemedicineOdds RatioHumanseducationTriglyceridesOriginal ResearchAgedAdvanced and Specialized Nursingeducation.field_of_studyPolymorphism Geneticbusiness.industryIncidenceHazard ratioOdds ratioFastingMiddle Agedmedicine.diseaseStrokeEndocrinologyDiabetes Mellitus Type 2Cardiovascular DiseasesFemalebusinessTCF7L2Transcription Factor 7-Like 2 ProteinDiabetes Care
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